Find all hotels by Independent in Santee, SC

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Compare rooms and suites by Independent in Santee with rates, reviews, and availability. Most hotels are fully refundable.

Peach Tree Inn
Front of property
Peach Tree Inn
2.5 star property
6.8 out of 10, (1000)
"Did like it "
The price is $70
$76 total
includes taxes & fees
Jun 4 - Jun 5
Peach Tree Inn
Bells Marina & Resort
Lake
Bells Marina & Resort
4.5 star property
9.0 out of 10, Wonderful, (40)
"We had the most relaxing trip at Bells Marina & Resort. Our room was clean, and we loved that the decor wasn’t typical generic hotel prints. Beware of the beds! They are so comfortable they practically suck you in. Everything was convenient to our room. The lake was right outside our door, which couldn’t have pleased us more. The store, diner, and rental boats were right there. We had planned some hiking, and we discussed renting an electric boat. In the end, we opted to sit by the lake and have...
The price is $92
$103 total
includes taxes & fees
Jun 18 - Jun 19
Bells Marina & Resort
Tom Charles Goat Island Fishing Retreat
Property grounds
Tom Charles Goat Island Fishing Retreat
9.8 out of 10, Exceptional, (36)
"I enjoyed my stay here. It is a very nice home. You can walk right out back and fish or just sit by the water. Water view when indoors is nice. Host was very responsive. Please know that you cannot take fish remains to the dump. They have signs, and they told us they do not accept them. When we asked how we should dispose of them, they told us they didn't know, but recommended we dig a hole. So, that was interesting. You only have access to the public dock, which isn't far. Short walk. I was...
Tom Charles Goat Island Fishing Retreat
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Come Relax in the Country
Smart TV
Come Relax in the Country
10.0 out of 10, Exceptional, (29)
"While this location isn’t for everyone, I was so happy with it! We stayed here for a bee keeping class in Holly Hill. Property owner was so nice, the home was very clean, and we were able to bring our 2 dogs! The fenced in front yard was my favorite! I was also really happy with how well stocked it was- tin foil, good pots/pans, comfortable bed, waters & drinks, fans in every room, plenty of dishes, and the water pressure in the shower was fantastic. I also felt safe here. Perfect little getaway...
The price is $94
$154 total
includes taxes & fees
Jun 4 - Jun 5
Come Relax in the Country
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Property grounds
Golf and Lake fun on Santee! Bring your boat or golf clubs!
9.8 out of 10, Exceptional, (20)
"This is the second time staying here. We Love it. It is so comfortable and welcoming. We had the best time with our family. Thank you again for all the comforts of home!"
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
10.0 out of 10, Exceptional, (120)
"Great location on Lake Marion. Dock is set up for fishing and we caught a few big ones. House itself is exactly as described. Maybe not the Ritz, but it's Lake Marion. It's perfect for what it is. Very nice screened in porch looking out over the water. Almost a low country feel to the property and views. About 5 min from 1-95 and 10 min from Santee Food Lion. Bedrooms were comfortable and the kitchen was equipped appropriately. Great location for a golf weekend as well - plenty of decent courses...
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
Exterior
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
9.6 out of 10, Exceptional, (14)
"We came down to play a 3 day golf tournament. This place was perfect for us to rest and relax after a long day of golf. Place was clean, nice & quiet. We hope to stay here again."
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
Interior
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
10.0 out of 10, Exceptional, (33)
"Condo was clean, well supplied and comfortable with a wonderful balcony on the lake. Our family had a great time fishing on the dock and all over the lake in our bass boat and caught some bass and a catfish. Jerry, the host has been available and very responsive during our whole trip! This is or 4th vacation here and is our favorite stay at Santee."
Waterfront 3 Bedroom / 3 Bath Condo w/ Boat Slip Available
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Property grounds
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
10.0 out of 10, Exceptional, (13)
"It was such a lovely, quiet, and peaceful place to stay. Everything was convenient and clean."
The price is $85
$172 total
includes taxes & fees
Jun 4 - Jun 5
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
New Lakefront Deck Home with Dock, Views
Beach nearby
New Lakefront Deck Home with Dock, Views
10.0 out of 10, Exceptional, (4)
"Enjoyed our stay! The owner was a very nice lady and we loved meeting Max too! Fishing was so much fun off the dock. Will be booking here again."
New Lakefront Deck Home with Dock, Views
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent Santee Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Santee, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Santee hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Santee Independent locations may even offer extra little benefits and discounts for frequent travelers.

Recent reviews of Santee hotels
Expedia verified reviews

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

5/5 Excellent
Great place to stay! The inside is super nice!
"Great home, updated and had everything you would need! Super nice decor & inside was very comfortable."
A verified traveler stayed at Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Posted 12 hours ago
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!