Santee Vacations from $314

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Your Santee Vacation

Enjoy unforgettable adventures when you book a vacation package to Santee. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like Santee State Park, Santee Cooper Country Club and Santee Outlets. Stop daydreaming and start traveling. Browse the many options on Expedia today and put your Santee vacation plans into action!

The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
Seven Oaks
Price was $429, price is now $314 per person
$314
per person
Dec 29 - Jan 2
found 21 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Columbia (CAE)
8.2/10 Very Good! (1,013 reviews)
Clean and convenient

Reviewed on Oct 21, 2025

Hilton Columbia Center

Hilton Columbia Center

3.5 out of 5
Downtown Columbia
Price was $843, price is now $665 per person
$665
per person
Dec 2 - Dec 7
found 1 day ago
Roundtrip flight included
New York (NYC) to Columbia (CAE)
8.8/10 Excellent! (1,006 reviews)
The hotel was great as always. My only request would be multiple coffee machines in the lobby. Otherwise, it's perfect. Room is clean and spacious, bed is sooooo comfortable. I wish I had their sheets. You can't beat the walkability of the hotel, just a block off the Vista!

Reviewed on Oct 23, 2025

Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista

3.5 out of 5
Downtown Columbia
Price was $507, price is now $404 per person
$404
per person
Dec 29 - Jan 2
found 21 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Columbia (CAE)
9.4/10 Exceptional! (1,114 reviews)
Room was very clean and comfortable; nice and friendly staff.

Reviewed on Oct 15, 2025

Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
Price was $432, price is now $356 per person
$356
per person
Dec 29 - Jan 2
found 21 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Columbia (CAE)
7.8/10 Good! (1,274 reviews)
The rooms were old and dirty. The tiles were pealing and the bathroom was over all dirty. The room doors opened outside. No where was that visible in the pictures. Breakfast was good but would not stay there again.

Reviewed on Oct 24, 2025

Hampton Inn Columbia-Downtown Historic District

Hampton Inn Columbia-Downtown Historic District

2.5 out of 5
Downtown Columbia
Price was $708, price is now $586 per person
$586
per person
Dec 2 - Dec 7
found 1 day ago
Roundtrip flight included
New York (NYC) to Columbia (CAE)
8.8/10 Excellent! (1,005 reviews)
The room was a clean and comfortable. The hotel was convenient to dining and shopping.

Reviewed on Oct 20, 2025

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Discover the most popular places to visit in Santee

Santee State Park

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

Santee State Park

Santee Cooper Country Club

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.

Santee Cooper Country Club

Santee National Golf Club

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.

Santee National Golf Club

Santee Hotel Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Oct 26 to Oct 27
$83 total
Oct 26 - Oct 27
Total with taxes and fees
7.8/10 Good! (1,373 reviews)
it was a niceplace.

Reviewed on Oct 22, 2025

Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Nov 2 to Nov 3
$109 total
Nov 2 - Nov 3
Total with taxes and fees
9/10 Wonderful! (566 reviews)
Excellent room

Reviewed on Oct 17, 2025

Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $144 total per night from Nov 2 to Nov 3
$144 total
Nov 2 - Nov 3
Total with taxes and fees
9.8/10 Exceptional! (1,006 reviews)
Nice place. Very friendly staff. Clean rooms. Beds were really hard. Breakfast was good.

Reviewed on Oct 14, 2025

Fairfield Inn & Suites by Marriott Santee
See all 290 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santee Vacation Packages

Santee Essential Information

Language
English
Currency
U.S dollars
Population
940
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Santee State Park, Santee Cooper Country Club and Santee National Golf Club

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Frequently asked questions

How much does a Santee vacation package cost?
Offering excellent value package deals from $314 on Expedia, you'll be surprised at how little a vacation to Santee costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santee?
If you're hoping to snag a cheap Santee vacation package, consider visiting in January, September and October. You're likely to find better prices on accommodations and flights during these quieter months — ideal for budget-conscious travelers.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Usually, a few days to a week will give you time to hit all the leading attractions and explore some hidden treasures along the way.
Is it worth booking a vacation package to Santee?
It's no wonder a Santee vacation is on the to-do list of many travelers. Major attractions like Santee State Park are just the beginning of things to see and do here.
How to find the best Santee package deals?
Use Expedia's handy filters to help you find some fabulous Santee package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Santee package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking stays and flights individually. Better still, you can customize your Santee trip to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santee trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.