Santee Vacations from $380

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Your Santee Vacation

Enjoy unforgettable adventures when you book a vacation package to Santee. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this lively city. If your trip to Santee includes some sightseeing, don't miss famous attractions like Santee State Park, Santee Cooper Country Club and Santee Outlets. Stop daydreaming and start traveling. Browse the many options on Expedia today and put your Santee vacation plans into action!

The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Executive Inn Ridgeway I-77

Executive Inn Ridgeway I-77

2.5 out of 5
Price was $459, price is now $380 per person
$380
per person
Sep 25 - Sep 29
found 10 hours ago
Roundtrip flight included
Chicago (CHI) to Columbia (CAE)
6.8/10 (224 reviews)
The people were friendly but the hotel was dirty and most things didn’t work like the lights. When I say dirty, I don’t mean a little. The building looked like it needed to be torn down.

Reviewed on Jun 25, 2026

Residence Inn by Marriott Columbia Northeast/Fort Jackson Area

Residence Inn by Marriott Columbia Northeast/Fort Jackson Area

3 out of 5
Price was $641, price is now $522 per person
$522
per person
Sep 2 - Sep 5
found 14 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Columbia (CAE)
9/10 Wonderful! (817 reviews)
A lot dust in the room else on top of the refrigerator

Reviewed on Jul 7, 2026

Affordable Suites Sumter SC

Affordable Suites Sumter SC

2.5 out of 5
Price was $871, price is now $745 per person
$745
per person
Aug 28 - Sep 4
found 11 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
9/10 Wonderful! (43 reviews)
We use this brand of hotel for business in Augusta for the masters tournament. This location was even better than the Augusta location. No complaints.

Reviewed on Jul 7, 2026

Country Inn & Suites by Radisson, Columbia Airport, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

2.5 out of 5
Price was $562, price is now $489 per person
$489
per person
Aug 22 - Aug 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
8.4/10 Very Good! (1,005 reviews)
yes

Reviewed on Jul 5, 2026

Hilton Columbia Center

Hilton Columbia Center

3.5 out of 5
Downtown Columbia
Price was $663, price is now $579 per person
$579
per person
Aug 22 - Aug 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Columbia (CAE)
8.8/10 Excellent! (1,005 reviews)
Our Room was clean and comfortable!

Reviewed on Jul 5, 2026

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Stay near popular Santee attractions

Santee State Park

8.0/10 (219 reviews)
Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife.
See properties

Santee Hotel Deals

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Aug 2 to Aug 3
$109 total
Aug 2 - Aug 3
Total with taxes and fees
9.2/10 Wonderful! (875 reviews)
"Property was clean. Staff very helpful."

Reviewed on Jul 7, 2026

Tru By Hilton Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Jul 15 to Jul 16
$87 total
Jul 15 - Jul 16
Total with taxes and fees
8/10 Very Good! (1,477 reviews)
"If you want a pool, stay elsewhere, no pool. Want a clean, quick stay, it’s for you."

Reviewed on Jul 7, 2026

Baymont by Wyndham Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $124 total per night from Jul 9 to Jul 10
$124 total
Jul 9 - Jul 10
Total with taxes and fees
8.8/10 Excellent! (1,003 reviews)
"What a super clean cute place to stay. If you like the idea of parking outside your door which I do. It’s so nice. It’s very clean and safe and well taken care of. Cute little area it’s in. A golf course next door. I would stay here again for sure. Priced really well and plenty of restaurants near ..."

Reviewed on Jul 3, 2026

Best Western Plus Santee Inn
See all 313 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santee Vacation Packages

Santee Essential Information

Language
English
Currency
U.S dollars
Population
940
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Santee State Park, Santee Cooper Country Club and Santee National Golf Club

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Frequently asked questions

How much does a Santee vacation package cost?
Offering excellent value package deals from $380 on Expedia, you'll be surprised at how little a vacation to Santee costs! Our packages make travel planning easier and your savings go further.
What are the cheapest months to go to Santee?
If you're hoping to snag a cheap Santee vacation package, consider visiting in January, September and October. You're likely to find better prices on accommodations and flights during these quieter months — ideal for budget-conscious travelers.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Usually, a few days to a week will give you time to hit all the leading attractions and explore some hidden treasures along the way.
Is it worth booking a vacation package to Santee?
It's no wonder a Santee vacation is on the to-do list of many travelers. Major attractions like Santee State Park are just the beginning of things to see and do here.
How to find the best Santee package deals?
Use Expedia's handy filters to help you find some fabulous Santee package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Santee package deals in the low season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking stays and flights individually. Better still, you can customize your Santee trip to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
If you're anything like us, you love discovering new places but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santee trip across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.