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Discover 1,162 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very Good, (1466)
"Conveniently located and excellent property. "
$88 nightly
The price is $103
Aug 3 - Aug 4
Total includes taxes and fees
Hilton Houston Plaza/Medical Center

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1725)
"Great stay!"
$223 nightly
The price is $261
Aug 5 - Aug 6
Total includes taxes and fees
Hotel Zaza Houston Museum District

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1004)
"Highly recommended.. I will stay again."
$83 nightly
The price is $97
Jul 24 - Jul 25
Total includes taxes and fees
Americas Best Value Inn Medical Center Downtown

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1006)
"Peaceful and relaxing stay."
$171 nightly
The price is $200
Aug 8 - Aug 9
Total includes taxes and fees
Houston Marriott Medical Center/Museum District

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (512)
"Nice property we are enjoying our stay. "
$175 nightly
The price is $205
Jul 30 - Jul 31
Total includes taxes and fees
La Maison in Midtown an urban B&B

Wanderstay Boutique Hotel

2.0 star property
9.8 out of 10, Exceptional, (39)
"Great stay!"
$129 nightly
The price is $150
Jul 27 - Jul 28
Total includes taxes and fees
Wanderstay Boutique Hotel

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very Good, (393)
"Very nice place clean nice towels good shower"
$107 nightly
The price is $125
Aug 3 - Aug 4
Total includes taxes and fees
DoubleTree by Hilton Houston Medical Center Hotel & Suites

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1013)
"Great place to stay "
$183 nightly
The price is $212
Aug 1 - Aug 2
Total includes taxes and fees
The Westin Houston Medical Center/Museum District

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1013)
"Very good hotel for visits to mD Anderson. Excellent facility and staff"
$172 nightly
The price is $198
Aug 3 - Aug 4
Total includes taxes and fees
InterContinental Houston by IHG

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (843)
"Awesome Hotel. "
$161 nightly
The price is $188
Jul 30 - Jul 31
Total includes taxes and fees
Hilton University of Houston

Luxurious 3 Bed3 Bath Near Downtown Houston

2.0 star property
10.0 out of 10, Exceptional, (1)
"This was made for a perfect family vacation… super clean kid friendly with an awesome view of Houston for the adults on rooftop "
$283 nightly
The price is $332
Jul 28 - Jul 29
Total includes taxes and fees
Luxurious 3 Bed3 Bath Near Downtown Houston

Downtown Houston 3BR Bachelorette Escape

2.0 star property
10.0 out of 10, Exceptional, (3)
"Everything was great. Look no further and book this property. "
$308 nightly
The price is $360
Jul 24 - Jul 25
Total includes taxes and fees
Downtown Houston 3BR Bachelorette Escape

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
$215 nightly
The price is $250
Aug 7 - Aug 8
Total includes taxes and fees
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Modern Cozy Home with King Bed

3.5 star property
9.6 out of 10, Exceptional, (17)
"Very spacious and close to just about everything. The view is amazing too"
$325 nightly
The price is $348
Jul 30 - Jul 31
Total includes taxes and fees
Modern Cozy Home with King Bed

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
$553 nightly
The price is $647
Jul 28 - Jul 29
Total includes taxes and fees
Paradise Palace Best Rooftop in HTX w Hot Tub

Luxury Med Center Fully Equipped King Sized Bed Condos

4.0 star property
8.4 out of 10, Very Good, (92)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
$255 nightly
The price is $282
Jul 27 - Jul 28
Total includes taxes and fees
Luxury Med Center Fully Equipped King Sized Bed Condos

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
Posh Dtwn Midtown Home w Stunning Roof-topterrace

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
$496 nightly
The price is $580
Jul 24 - Jul 25
Total includes taxes and fees
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

The Oasis Checkmate HTX Rooftop

3.0 star property
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
$616 nightly
The price is $721
Jul 28 - Jul 29
Total includes taxes and fees
The Oasis Checkmate HTX Rooftop

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1008)
"Very clean and peaceful place to stay close to the hospital 🏥 "
$83 nightly
The price is $97
Jul 29 - Jul 30
Total includes taxes and fees
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
Downtown Houston map

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria map

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center map

Texas Medical Center

2 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose map

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Find out more about South Central Houston

Find out more about South Central Houston

Top reasons to visit South Central Houston

  • Vibrant Cultural Scene: Experience a rich blend of art, history, and local traditions through museums, historic colleges, and live music events.
  • Sports Enthusiasm: Enjoy attending exciting sports events, making it a great destination for sports fans.
  • Diverse Accommodations: Choose from a wide range of hotels, including budget-friendly and luxurious options tailored to various needs.
  • Family-Friendly Activities: Explore family-oriented attractions and local charm in nearby neighborhoods.
  • Dynamic Downtown Atmosphere: Discover the bustling city center with shopping, dining, and entertainment.

Find great hotels near South Central Houston

Discover a variety of hotel accommodations in South Central Houston, catering to every traveler's needs, from budget-friendly options to luxurious stays. Whether you're seeking a pet-friendly environment, LGBTQIA-welcoming spaces, or business-focused amenities, you'll find the perfect fit among the diverse selection of hotels and aparthotels. Experience the vibrant culture and hospitality of Houston while enjoying a comfortable and convenient stay.

  • Club Quarters Hotel Downtown, Houston: Nestled in the vibrant shopping district, Club Quarters Hotel Downtown, Houston is a prime choice for business travelers and pet owners alike. This 4-star hotel, located 2 miles from South Central Houston, offers a business-friendly atmosphere with an array of amenities including 24-hour business center access and multiple meeting rooms. Guests can bring their furry friends along, as the hotel welcomes dogs with complimentary food and water bowls. With its modern facilities and convenient location, it’s an excellent option for those looking to blend work and leisure.
  • DoubleTree by Hilton Hotel & Suites Houston by the Galleria: Ideal for families and shopping enthusiasts, the DoubleTree by Hilton Hotel & Suites Houston by the Galleria offers a delightful stay 6 miles from South Central Houston. This 4-star hotel provides child-friendly amenities, including cribs and window guards for safety. Located in the heart of the city, guests can enjoy easy access to shopping and dining options. Known for its warm hospitality, the hotel’s signature chocolate chip cookies upon arrival add a sweet touch to your family getaway.
  • The Royal Sonesta Houston Galleria: For a luxurious experience that caters to both business and pet-friendly travelers, The Royal Sonesta Houston Galleria is a fantastic choice. Situated 6 miles away from South Central Houston, this 4-star hotel combines sophisticated accommodations with business amenities like a conference center and multiple meeting rooms. Pets are welcome, with specific restrictions in place to ensure a comfortable stay for all guests. Located in a bustling shopping district, this hotel provides a perfect blend of elegance and convenience.

Where to stay near South Central Houston

South Central Houston offers a vibrant mix of business, culture, and sports, making it an ideal vacation destination. Explore the dynamic atmosphere of Downtown Houston, with its bustling city center and diverse art scene. Just a short drive away, South Houston and Southeast Houston provide family-friendly options and local charm. Whether you're attending a sports event or enjoying the urban culture, South Central Houston promises an unforgettable travel experience.

  • Houston: As a vibrant metropolis, Houston is a melting pot of culture, commerce, and entertainment. South Central Houston is nestled within this bustling city, which sees a consistent influx of travelers year-round, with peaks in March, July, and October. Visitors flock here for family outings, business meetings, and a rich urban experience. From massive shopping malls to lively music concerts, the city offers endless activities. Don't miss local landmarks like the impressive sports stadiums and serene lakes that provide a refreshing escape in the heart of the city.
  • Downtown Houston: Located a mere 2 miles from South Central Houston, Downtown Houston is the city's energetic core. It attracts visitors throughout the year, particularly in April and during the summer months. This neighborhood is a hub for families, business travelers, and sports fans alike. Enjoy a variety of experiences, from exhilarating music concerts to shopping at premier retail centers. Key attractions include sports stadiums and conference venues, making it a prime spot for events and gatherings. The vibrant atmosphere here guarantees an engaging experience for every type of traveler.
  • Greater Third Ward: Just 0.7 miles from South Central Houston, the Greater Third Ward is rich in culture and history. This neighborhood sees a steady flow of visitors, especially from February to April, who come for business, cultural experiences, and sports events. Here, you can explore educational institutions, catch a live music show, or shop at local centers. With landmarks like historic colleges and sports facilities, the Greater Third Ward offers a unique blend of cultural richness and community spirit, making it a must-visit during your stay.

Things to do near South Central Houston

South Central Houston is a vibrant destination perfect for business trips, city explorations, and sports enthusiasts. Visitors can enjoy a variety of activities including educational experiences, live music concerts, and shopping at local centers. This area presents a unique blend of culture and entertainment, making it an exciting place to explore during your vacation.

Shopping

In South Central Houston, you can shop at River Oaks District, only 5 miles away, featuring a vibrant mix of boutiques. The Galleria and Uptown Park are both 6 miles away, offering a variety of family-friendly shops and entertainment options. If you're up for a drive, explore even more nearby malls.

Recreation

At the Toyota Center, immerse yourself in an electrifying atmosphere as you catch a thrilling sports event. Experience vibrant live music at the House of Blues Houston, where entertainment and energy collide. For a tranquil outdoor escape, enjoy a round of golf at the Memorial Park Municipal Golf Course, surrounded by nature.

Adventure

Experience the thrill of flight at iFLY Indoor Skydiving, located 11 miles from South Central Houston, where you can soar in a safe, controlled environment. For tennis enthusiasts, Homer Ford Tennis Center, 2 miles away, and Memorial Park Tennis Center, 6 miles away, offer exciting matches in vibrant outdoor settings.

Nightlife

In South Central Houston, the Hobby Center for the Performing Arts offers a cultural experience with captivating performances. For a lively night out, Bayou Place nightclub provides city vibes and entertainment. Don't miss Sundance Cinema for a romantic movie night with family-friendly options.

Booking tips and Expedia advantages for South Central Houston

To save money during your visit to South Central Houston, consider traveling between November and January when hotel prices are lower, and aim for Sunday stays to avoid Saturday's peak rates. Use Expedia to compare hotel rates, filter for eco-certified options, and combine bookings for flights and activities to snag better deals. Joining Expedia's One Key membership can provide exclusive discounts and earn OneKeyCash for future stays. Also, take advantage of public transport for cost-effective travel around the city and explore free attractions to maximize your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around South Central Houston are November to January, where the prices are slightly lower. This is in comparison to March to May, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around South Central Houston is Sunday. The most expensive day to stay around South Central Houston is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to tailor your travel options based on your budget, desired location, and preferred hotel type. For instance, selecting the "Eco-certified" filter will showcase sustainable and environmentally-friendly hotels currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in South Central Houston with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in and around South Central Houston

South Central Houston offers a vibrant mix of experiences ideal for business and sports vacations, alongside rich cultural exploration. Visitors can immerse themselves in the local scene by visiting historic colleges and universities, engaging in events at conference venues, or appreciating the art at museums. This area caters to families and travelers seeking a dynamic city experience filled with history and culture.

  • George R. Brown Convention Center: Located 2 miles from South Central Houston, this modern event space hosts a variety of conventions and conferences, making it a hub of business activity. Its expansive facilities and professional atmosphere provide a unique experience for visitors looking to connect with industry leaders and trends.
  • Rice University: Nestled in South Central Houston, Rice University boasts stunning architecture and beautiful green spaces. This vibrant campus offers a blend of academic excellence and city energy, perfect for a leisurely stroll or exploring art installations.
  • University of Houston: Situated 1 mile away, the University of Houston is rich in history and culture. Visitors can immerse themselves in its artistic programs, vibrant campus life, and diverse student body, making it a cultural landmark in the area.

Best time to go to South Central Houston

Visitor numbers around South Central Houston is generally unchanged in popularity throughout the year. The best time to visit South Central Houston can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around South Central Houston falls in August, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around South Central Houston falls in January, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January54.1°F (12.3°C)Light RainMostly SunnySlightly LowSlightly Low
February57.0°F (13.9°C)Light RainMostly CloudyAverageAverage
March63.9°F (17.7°C)Light RainMostly SunnySlightly HighSlightly High
April69.6°F (20.9°C)Light RainMostly SunnyAverageSlightly High
May76.6°F (24.8°C)Light RainMostly SunnyAverageSlightly High
June82.8°F (28.2°C)Light RainMostly SunnyAverageAverage
July84.2°F (29.0°C)Light RainMostly SunnySlightly HighAverage
August84.9°F (29.4°C)Light RainMostly SunnyAverageAverage
September80.6°F (27.0°C)Light RainMostly SunnySlightly LowAverage
October72.7°F (22.6°C)Light RainMostly SunnySlightly HighAverage
November62.8°F (17.1°C)Light RainMostly SunnyAverageSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to South Central Houston

Traveling to South Central Houston is convenient with access to three major airports. Houston, TX (IAH-George Bush Intercontinental) is 18 miles away, with nearby hotels like Sonesta Hotel Houston IAH Airport, 5 miles from the terminal, offering free airport transportation. DoubleTree by Hilton Houston Intercontinental Airport is only 3 miles away. Houston, TX (HOU-William P. Hobby) is 7 miles from South Central Houston, with luxurious options such as JW Marriott Houston Downtown and Four Seasons Hotel, both 9 miles away. Lastly, Houston, TX (EFD-Ellington Field) is located 14 miles away, featuring Doubletree by Hilton Houston Hobby Airport, just 7 miles away, providing easy access to the airport.

Frequently asked questions

What are the best hotels in South Central Houston that travelers recommend?
Hotel Zaza Houston Museum District stands out as a top choice for travelers, boasting an excellent review score of 8.8. This stylish hotel combines luxury and comfort, superb for those seeking a vibrant stay in Houston. Guests rave about the on-site full-service spa, where you can indulge in a range of treatments from body scrubs to aromatherapy, ensuring relaxation and rejuvenation during your getaway. The unique décor and upscale ambiance make it a memorable spot, whether you're unwinding by the outdoor pool or enjoying a cocktail at the poolside bar.
What are the best family hotels in South Central Houston?
Hotel Zaza Houston Museum District is a fantastic choice for families visiting South Central Houston, boasting an excellent traveler review rating of 8.8. This vibrant hotel greatly blends luxury and comfort, making it an ideal base for family adventures.
What are the best spa hotels in South Central Houston?
For a rejuvenating escape in South Central Houston, Hotel Zaza Houston Museum District is a great choice, boasting an excellent review score of 8.8 out of 10. This hotel features a full-service spa where guests can indulge in a variety of treatments, including body scrubs, massages, and aromatherapy treatments, ensuring a truly relaxing experience.
What are the most romantic hotels in South Central Houston for couples?
For a romantic getaway in South Central Houston, Hotel Zaza Houston Museum District is an exceptional choice, boasting a review score of 8.8/10. This luxurious hotel offers couples a unique blend of comfort and charm, making it a superb retreat for those looking to spend quality time together.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right South Central Houston hotel for you.
How can I save on a South Central Houston hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible South Central Houston hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a South Central Houston hotel?
Hotel prices in South Central Houston often vary, but you can find a great deal from $97 on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.