$130 Cheap American Airlines flights Asheville (AVL) to San Diego (SAN)

Landing cheap one-way American Airlines flights from AVL to SAN from $130 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Or check out our budget-friendly round-trip fares from $259 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Asheville Regional Airport (AVL) to San Diego Intl. Airport (SAN) one to three months before your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the best day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find American Airlines's earliest flights from AVL to SAN by selecting the "Morning" and "Early Morning" filters. Not only will you arrive sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.