$577 Cheap American Airlines flights Santa Cruz de Tenerife (TFN) to San Diego (SAN)

Scoring cheap one-way American Airlines flights from TFN to SAN from $577 on Expedia is easy — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Scoring the best American Airlines deals from TFN to SAN often comes down to booking at the right time. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. As an added bonus, you can pocket 17% on average by buying your fare on a Sunday compared to a Friday, which is usually the most expensive day to book.* It's smart to kick off your flight search about one month before you want to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find American Airlines's earliest flights from TFN to SAN by selecting the "Early Morning" and "Morning" filters. Not only will you get to your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.