$1,595 Cheap Brussels Airlines flights Brussels (BRU) to San Diego (SAN)

Landing cheap one-way Brussels Airlines flights from BRU to SAN from $1,595 on Expedia is a cinch — just filter by "Price (lowest to highest)." Or check out our affordable return fares from $832 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Getting the best Brussels Airlines deals from BRU to SAN often comes down to timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. What's more, you can pocket 17% on average by buying your tickets on a Sunday rather than a Friday, which is usually the most expensive day to book.* It's a good idea to start checking out flights about one month before you want to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from BRU to SAN with Brussels Airlines, sort your results by "Morning" and "Early Morning." Choosing an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Fly from BRU to SAN with Brussels Airlines and you can look forward to a host of benefits starting with a rewarding loyalty program. When booking through Expedia as a Miles and More and One Key™ member, you may also earn OneKeyCash™* to use on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.