$159 Cheap Flights from Cleveland (CLE) to Guayaquil (GYE)

View $159 flight on Sat, Jan 24, 2026Opens in a new window

Popular airlines from Cleveland Hopkins International Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE)

Cheap Flights from Cleveland to Guayaquil (CLE-GYE)

Prices were available within the past 7 days and start at $159 for one-way flights and $315 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Tue, Jan 27 - Mon, Feb 2
CLE
Cleveland
GYE
Guayaquil
$315 Roundtrip, found 3 days ago
$315
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Jan 27 from Cleveland to Guayaquil, returning Mon, Feb 2, priced at $315 found 3 days ago
JetBlue Airways
Tue, Jan 27 - Mon, Feb 2
CLE
Cleveland
GYE
Guayaquil
$320 Roundtrip, found 3 days ago
$320
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Jan 27 from Cleveland to Guayaquil, returning Mon, Feb 2, priced at $320 found 3 days ago
JetBlue Airways
Sat, Jan 24 - Mon, Feb 2
CLE
Cleveland
GYE
Guayaquil
$327 Roundtrip, found 3 days ago
$327
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sat, Jan 24 from Cleveland to Guayaquil, returning Mon, Feb 2, priced at $327 found 3 days ago
JetBlue Airways
Sat, Jan 24 - Mon, Feb 2
CLE
Cleveland
GYE
Guayaquil
$332 Roundtrip, found 3 days ago
$332
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sat, Jan 24 from Cleveland to Guayaquil, returning Mon, Feb 2, priced at $332 found 3 days ago
JetBlue Airways
Tue, Jan 27 - Mon, Feb 2
CLE
Cleveland
GYE
Guayaquil
$355 Roundtrip, found 3 days ago
$355
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Tue, Jan 27 from Cleveland to Guayaquil, returning Mon, Feb 2, priced at $355 found 3 days ago
JetBlue Airways
Sat, Jan 24 - Mon, Feb 2
CLE
Cleveland
GYE
Guayaquil
$359 Roundtrip, found 3 days ago
$359
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sat, Jan 24 from Cleveland to Guayaquil, returning Mon, Feb 2, priced at $359 found 3 days ago
Spirit Airlines
Wed, Dec 31 - Thu, Jan 8
CLE
Cleveland
GYE
Guayaquil
$453 Roundtrip, found 20 hours ago
$453
Roundtrip
found 20 hours ago
Select Spirit Airlines flight, departing Wed, Dec 31 from Cleveland to Guayaquil, returning Thu, Jan 8, priced at $453 found 20 hours ago
American Airlines
Mon, Feb 23 - Wed, Mar 4
CLE
Cleveland
GYE
Guayaquil
$584 Roundtrip, found 1 day ago
$584
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Feb 23 from Cleveland to Guayaquil, returning Wed, Mar 4, priced at $584 found 1 day ago
United
Tue, Mar 24 - Tue, Apr 14
CLE
Cleveland
GYE
Guayaquil
$587 Roundtrip, found 1 day ago
$587
Roundtrip
found 1 day ago
Select United flight, departing Tue, Mar 24 from Cleveland to Guayaquil, returning Tue, Apr 14, priced at $587 found 1 day ago
LATAM Airlines Group
Wed, Feb 18 - Wed, Mar 11
CLE
Cleveland
GYE
Guayaquil
$604 Roundtrip, found 3 days ago
$604
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, Feb 18 from Cleveland to Guayaquil, returning Wed, Mar 11, priced at $604 found 3 days ago

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $810
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $810
Flights from Cleveland (CLE) to Guayaquil (GYE)
Origin airport
Hopkins Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, LATAM Airlines Group, Spirit Airlines, United, avianca
Roundtrip price
$314
Distance
3011 mi

Cleveland to Guayaquil Flights

The cheapest times to fly from Cleveland to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cleveland to Guayaquil are during the month of January. You can find some of the cheapest flights from Cleveland to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cleveland to Guayaquil

Sunday is one of the best days to book for cheap flights from Cleveland to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cleveland to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cleveland to Guayaquil in 2026. You can also book with separate airlines for your outbound and return journeys, from $159 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cleveland to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cleveland to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Grab a cheap one-way flight from $159 or cheap return flight from $315 from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
January is the most affordable month to fly from CLE to GYE. Planning your trip for the off-season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
To find the cheapest airline that'll fly you from CLE to GYE, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
You'll need to hop on a flight with a layover if you're traveling from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from CLE to GYE?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on a range of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
To avoid possible delays on the Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Last-minute bookings from CLE to GYE are typically more expensive. To lock in the cheapest rates, start looking for flights as early as possible. That said, if your travel plans are flexible, you may land a cheap ticket right before your journey.
Is it cheaper to book a CLE to GYE flight and hotel package?
Compared with arranging flights and hotels separately, booking a CLE to GYE flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one easy place will take the hassle out of planning your trip. Simply secure your flights and select from our extensive range of stays, then customize your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Hopkins Intl. Airport (CLE) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Usually, it's possible to reschedule or cancel your CLE to GYE flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.