$299 Cheap Flights from Champaign (CMI) to Knoxville (TYS)

View $299 flight on Sat, Aug 30, 2025Opens in a new window

Popular airlines from Champaign, IL (CMI-University Of Illinois Urbana-Champaign Williard) to McGhee Tyson Airport (TYS)

Cheap Flights from Champaign to Knoxville (CMI-TYS)

Prices were available within the past 7 days and start at $299 for one-way flights and $308 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Nov 15 - Tue, Nov 18
CMI
Champaign
TYS
Knoxville
$308 Roundtrip, found 3 hours ago
$308
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sat, Nov 15 from Champaign to Knoxville, returning Tue, Nov 18, priced at $308 found 3 hours ago
American Airlines
Mon, Aug 18 - Mon, Aug 25
CMI
Champaign
TYS
Knoxville
$313 Roundtrip, found 13 hours ago
$313
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Aug 18 from Champaign to Knoxville, returning Mon, Aug 25, priced at $313 found 13 hours ago
American Airlines
Fri, Aug 15 - Sat, Aug 16
CMI
Champaign
TYS
Knoxville
$318 Roundtrip, found 6 days ago
$318
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Aug 15 from Champaign to Knoxville, returning Sat, Aug 16, priced at $318 found 6 days ago
American Airlines
Thu, Sep 18 - Sat, Sep 20
CMI
Champaign
TYS
Knoxville
$358 Roundtrip, found 13 hours ago
$358
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Thu, Sep 18 from Champaign to Knoxville, returning Sat, Sep 20, priced at $358 found 13 hours ago
American Airlines
Sat, Aug 16 - Sat, Aug 23
CMI
Champaign
TYS
Knoxville
$363 Roundtrip, found 9 hours ago
$363
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Champaign to Knoxville, returning Sat, Aug 23, priced at $363 found 9 hours ago
American Airlines
Sat, Nov 15 - Tue, Nov 18
CMI
Champaign
TYS
Knoxville
$368 Roundtrip, found 3 hours ago
$368
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sat, Nov 15 from Champaign to Knoxville, returning Tue, Nov 18, priced at $368 found 3 hours ago
American Airlines
Sat, Aug 16 - Tue, Aug 26
CMI
Champaign
TYS
Knoxville
$373 Roundtrip, found 13 hours ago
$373
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Champaign to Knoxville, returning Tue, Aug 26, priced at $373 found 13 hours ago
American Airlines
Sat, Aug 16 - Fri, Aug 22
CMI
Champaign
TYS
Knoxville
$378 Roundtrip, found 13 hours ago
$378
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Aug 16 from Champaign to Knoxville, returning Fri, Aug 22, priced at $378 found 13 hours ago
American Airlines
Fri, Aug 15 - Fri, Aug 22
CMI
Champaign
TYS
Knoxville
$383 Roundtrip, found 13 hours ago
$383
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, Aug 15 from Champaign to Knoxville, returning Fri, Aug 22, priced at $383 found 13 hours ago
American Airlines
Sat, Aug 9 - Sun, Aug 17
CMI
Champaign
TYS
Knoxville
$389 Roundtrip, found 4 days ago
$389
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Aug 9 from Champaign to Knoxville, returning Sun, Aug 17, priced at $389 found 4 days ago

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $373
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $373
Flights from Champaign (CMI) to Knoxville (TYS)
Origin airport
University Of Illinois Urbana-Champaign Williard
Destination airport
McGhee Tyson
Airlines serving
American Airlines
Roundtrip price
$308
Distance
373 mi

Champaign to Knoxville Flights

The cheapest times to fly from Champaign to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Champaign to Knoxville are during the month of November. You can find some of the cheapest flights from Champaign to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Champaign to Knoxville

Sunday is one of the best days to book for cheap flights from Champaign to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Champaign to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Champaign to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $299 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Champaign to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Champaign to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS) cost?
Discover the latest flight deals from CMI to TYS by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CMI to TYS?
The cheapest flights from CMI to TYS are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from CMI to TYS?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from CMI to TYS. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS)?
You'll need to hop on a flight with a layover when traveling from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from CMI to TYS?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on various factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS)?
Book a flight from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS) last-minute?
Booking your ticket from CMI to TYS right before your getaway is typically more expensive. However, if there's some wiggle room with your travel dates and times, you could score a cheap last-minute fare.
Is it cheaper to book a CMI to TYS flight and hotel package?
Compared with arranging hotels and flights separately, booking a CMI to TYS flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one convenient place takes the hassle out of planning your trip. Just pick your flights and choose from our extensive range of hotels, then tailor your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from University Of Illinois Urbana-Champaign Williard Airport (CMI) to McGhee Tyson Airport (TYS)?
If you booked your CMI to TYS flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Explore a world of travel with Expedia

*Available to One Key members.