$273 Cheap Flights from Des Moines (DSM) to Cartagena (CTG)

View $273 flight on Fri, Oct 17, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Rafael Nunez Intl. Airport (CTG)

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Cheap Flights from Des Moines to Cartagena (DSM-CTG)

Prices were available within the past 7 days and start at $273 for one-way flights and $570 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Mon, Jan 12 - Tue, Jan 20
DSM
Des Moines
CTG
Cartagena
$570 Roundtrip, found 3 days ago
$570
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Jan 12 from Des Moines to Cartagena, returning Tue, Jan 20, priced at $570 found 3 days ago
Delta
Fri, Jan 9 - Tue, Jan 20
DSM
Des Moines
CTG
Cartagena
$575 Roundtrip, found 3 days ago
$575
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Jan 9 from Des Moines to Cartagena, returning Tue, Jan 20, priced at $575 found 3 days ago
United
Fri, Oct 17 - Mon, Oct 20
DSM
Des Moines
CTG
Cartagena
$579 Roundtrip, found 2 days ago
$579
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 17 from Des Moines to Cartagena, returning Mon, Oct 20, priced at $579 found 2 days ago
Delta
Sun, Jan 11 - Tue, Jan 20
DSM
Des Moines
CTG
Cartagena
$580 Roundtrip, found 3 days ago
$580
Roundtrip
found 3 days ago
Select Delta flight, departing Sun, Jan 11 from Des Moines to Cartagena, returning Tue, Jan 20, priced at $580 found 3 days ago
Delta
Tue, Oct 14 - Wed, Oct 22
DSM
Des Moines
CTG
Cartagena
$583 Roundtrip, found 2 days ago
$583
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Oct 14 from Des Moines to Cartagena, returning Wed, Oct 22, priced at $583 found 2 days ago
Delta
Sat, Jan 10 - Tue, Jan 20
DSM
Des Moines
CTG
Cartagena
$585 Roundtrip, found 3 days ago
$585
Roundtrip
found 3 days ago
Select Delta flight, departing Sat, Jan 10 from Des Moines to Cartagena, returning Tue, Jan 20, priced at $585 found 3 days ago
United
Fri, Oct 17 - Mon, Oct 20
DSM
Des Moines
CTG
Cartagena
$594 Roundtrip, found 2 days ago
$594
Roundtrip
found 2 days ago
Select United flight, departing Fri, Oct 17 from Des Moines to Cartagena, returning Mon, Oct 20, priced at $594 found 2 days ago
American Airlines
Sun, Oct 19 - Sun, Oct 26
DSM
Des Moines
CTG
Cartagena
$601 Roundtrip, found 5 days ago
$601
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Oct 19 from Des Moines to Cartagena, returning Sun, Oct 26, priced at $601 found 5 days ago
LATAM Airlines Group
Wed, Dec 10 - Tue, Jan 13
DSM
Des Moines
CTG
Cartagena
$642 Roundtrip, found 5 hours ago
$642
Roundtrip
found 5 hours ago
Select LATAM Airlines Group flight, departing Wed, Dec 10 from Des Moines to Cartagena, returning Tue, Jan 13, priced at $642 found 5 hours ago
Copa
Mon, Oct 20 - Mon, Oct 27
DSM
Des Moines
CTG
Cartagena
$1,282 Roundtrip, found 6 days ago
$1,282
Roundtrip
found 6 days ago
Select Copa flight, departing Mon, Oct 20 from Des Moines to Cartagena, returning Mon, Oct 27, priced at $1,282 found 6 days ago
Flights from Des Moines (DSM) to Cartagena (CTG)
Origin airport
Des Moines Intl.
Destination airport
Rafael Núñez Intl.
Airlines serving
LATAM Airlines Group
Roundtrip price
$570
Distance
2413 mi

Des Moines to Cartagena Flights

The cheapest times to fly from Des Moines to Cartagena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Cartagena are during the month of January. You can find some of the cheapest flights from Des Moines to Cartagena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Cartagena

Sunday is one of the best days to book for cheap flights from Des Moines to Cartagena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Cartagena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Cartagena in 2025. You can also book with separate airlines for your outbound and return journeys, from $273 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Cartagena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Cartagena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) cost?
Get a cheap one-way flight from $273 or cheap return flight from $570 from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
January is the cheapest month to fly from DSM to CTG. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
To find the cheapest airline that'll fly you from DSM to CTG, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
You'll need to take a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from DSM to CTG?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change depending on a range of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
To avoid possible delays on the Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) route, aim to travel before 3 PM. Later departures are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG) last-minute?
Waiting until right before your break to book your flight from DSM to CTG often results in higher prices. While you may come across some last-minute discounts, there's no guarantee. Keep your travel plans flexible for the best chance of getting a bargain.
Is it cheaper to book a DSM to CTG flight and hotel package?
You can save money by securing a DSM to CTG flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've chosen your preferred flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Rafael Nunez Intl. Airport (CTG)?
In most cases, you can modify or cancel your DSM to CTG flight. However, additional fees may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need further details, visit our Customer Service portal.

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*Available to One Key members.