$555 Cheap Flights from Kirksville (IRK) to St. Louis (STL)

View $555 flight on Sat, Nov 22, 2025Opens in a new window

Popular airlines from Kirksville, MO (IRK-Kirksville Municipal) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Kirksville to St. Louis (IRK-STL)

Prices were available within the past 7 days and start at $555 for one-way flights and $386 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Contour Airlines
Mon, Nov 17 - Wed, Nov 19
IRK
Kirksville
STL
St. Louis
$386 Roundtrip, found 6 days ago
$386
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Mon, Nov 17 from Kirksville to St. Louis, returning Wed, Nov 19, priced at $386 found 6 days ago
Contour Airlines
Tue, Nov 11 - Tue, Nov 18
IRK
Kirksville
STL
St. Louis
$456 Roundtrip, found 6 days ago
$456
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Tue, Nov 11 from Kirksville to St. Louis, returning Tue, Nov 18, priced at $456 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$481 Roundtrip, found 6 days ago
$481
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $481 found 6 days ago
Contour Airlines
Mon, Nov 17 - Tue, Nov 18
IRK
Kirksville
STL
St. Louis
$506 Roundtrip, found 6 days ago
$506
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Mon, Nov 17 from Kirksville to St. Louis, returning Tue, Nov 18, priced at $506 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$507 Roundtrip, found 6 days ago
$507
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $507 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$526 Roundtrip, found 6 days ago
$526
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $526 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$596 Roundtrip, found 6 days ago
$596
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $596 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$659 Roundtrip, found 6 days ago
$659
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $659 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$676 Roundtrip, found 6 days ago
$676
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $676 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$729 Roundtrip, found 6 days ago
$729
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $729 found 6 days ago
Contour Airlines
Mon, Nov 17 - Thu, Nov 20
IRK
Kirksville
STL
St. Louis
$731 Roundtrip, found 6 days ago
$731
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Mon, Nov 17 from Kirksville to St. Louis, returning Thu, Nov 20, priced at $731 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$746 Roundtrip, found 6 days ago
$746
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $746 found 6 days ago
Contour Airlines
Sun, Nov 16 - Tue, Nov 18
IRK
Kirksville
STL
St. Louis
$755 Roundtrip, found 6 days ago
$755
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Sun, Nov 16 from Kirksville to St. Louis, returning Tue, Nov 18, priced at $755 found 6 days ago
Contour Airlines
Sun, Nov 16 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$780 Roundtrip, found 6 days ago
$780
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Sun, Nov 16 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $780 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$799 Roundtrip, found 6 days ago
$799
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $799 found 6 days ago
Contour Airlines
Tue, Nov 11 - Thu, Nov 20
IRK
Kirksville
STL
St. Louis
$801 Roundtrip, found 6 days ago
$801
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Tue, Nov 11 from Kirksville to St. Louis, returning Thu, Nov 20, priced at $801 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$807 Roundtrip, found 6 days ago
$807
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $807 found 6 days ago
Contour Airlines
Fri, Nov 14 - Mon, Nov 17
IRK
Kirksville
STL
St. Louis
$838 Roundtrip, found 6 days ago
$838
Roundtrip
found 6 days ago
Select Contour Airlines flight, departing Fri, Nov 14 from Kirksville to St. Louis, returning Mon, Nov 17, priced at $838 found 6 days ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $456
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $456

Frequently asked questions

How much does a flight from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL) cost?
Grab a cheap one-way flight from $555 or cheap return flight from $386 from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL)?
Traveling in November is a good way to save, as it's the cheapest month for flights between IRK and STL. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest IRK to STL flight.
How many flights per day from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL)?
There are no daily nonstop flights available from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from IRK to STL?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL)?
To reach Lambert-St. Louis Intl. Airport (STL) on schedule, pick a flight that leaves Kirksville Municipal Airport (IRK) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Last-minute bookings from IRK to STL are typically more expensive. To lock in the lowest prices, start looking for flights as early as possible. That said, if you can play around with your travel dates, you may find a cheap fare right before your trip.
Is it cheaper to book an IRK to STL flight and hotel package?
You can save money by booking an IRK to STL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your ideal accommodations and flights, consider adding extras including car rentals, tours and activities.
Can I cancel or change the date of my flight from Kirksville Municipal Airport (IRK) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it's possible to cancel or reschedule your IRK to STL flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Kirksville Municipal
Destination airport
Lambert-St. Louis Intl.
Roundtrip price
$386
Distance
148 mi

Book with confidence

Kirksville to St. Louis Flights

The cheapest times to fly from Kirksville to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Kirksville to St. Louis are during the month of November. You can find some of the cheapest flights from Kirksville to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Kirksville to St. Louis

Sunday is one of the best days to book for cheap flights from Kirksville to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Kirksville to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Kirksville to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $555 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Kirksville to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Kirksville to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Kirksville to St. Louis Flights

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*Available to One Key members.