$514 Cheap Flights from Lyon (LYS) to Panama City (ECP)

View $514 flight on Mon, Dec 15, 2025Opens in a new window

Popular airlines from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Lyon to Panama City (LYS-ECP)

Prices were available within the past 7 days and start at $514 for one-way flights and $767 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Nov 4 - Sun, Nov 9
LYS
Lyon
ECP
Panama City
$767 Roundtrip, found 11 hours ago
$767
Roundtrip
found 11 hours ago
Select United flight, departing Tue, Nov 4 from Lyon to Panama City, returning Sun, Nov 9, priced at $767 found 11 hours ago
United
Sat, Nov 1 - Sat, Nov 8
LYS
Lyon
ECP
Panama City
$771 Roundtrip, found 11 hours ago
$771
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Nov 1 from Lyon to Panama City, returning Sat, Nov 8, priced at $771 found 11 hours ago
United
Sat, Nov 1 - Sun, Nov 9
LYS
Lyon
ECP
Panama City
$778 Roundtrip, found 11 hours ago
$778
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Nov 1 from Lyon to Panama City, returning Sun, Nov 9, priced at $778 found 11 hours ago
United
Tue, Nov 4 - Mon, Nov 10
LYS
Lyon
ECP
Panama City
$780 Roundtrip, found 11 hours ago
$780
Roundtrip
found 11 hours ago
Select United flight, departing Tue, Nov 4 from Lyon to Panama City, returning Mon, Nov 10, priced at $780 found 11 hours ago
United
Sun, Nov 2 - Sat, Nov 8
LYS
Lyon
ECP
Panama City
$856 Roundtrip, found 11 hours ago
$856
Roundtrip
found 11 hours ago
Select United flight, departing Sun, Nov 2 from Lyon to Panama City, returning Sat, Nov 8, priced at $856 found 11 hours ago
Delta
Fri, Nov 7 - Sun, Nov 9
LYS
Lyon
ECP
Panama City
$866 Roundtrip, found 11 hours ago
$866
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Nov 7 from Lyon to Panama City, returning Sun, Nov 9, priced at $866 found 11 hours ago
Delta
Fri, Nov 7 - Mon, Nov 10
LYS
Lyon
ECP
Panama City
$872 Roundtrip, found 11 hours ago
$872
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Nov 7 from Lyon to Panama City, returning Mon, Nov 10, priced at $872 found 11 hours ago
American Airlines
Mon, Nov 3 - Sun, Nov 9
LYS
Lyon
ECP
Panama City
$921 Roundtrip, found 11 hours ago
$921
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, Nov 3 from Lyon to Panama City, returning Sun, Nov 9, priced at $921 found 11 hours ago
Air France
Tue, Nov 4 - Fri, Nov 7
LYS
Lyon
ECP
Panama City
$1,300 Roundtrip, found 11 hours ago
$1,300
Roundtrip
found 11 hours ago
Select Air France flight, departing Tue, Nov 4 from Lyon to Panama City, returning Fri, Nov 7, priced at $1,300 found 11 hours ago
Iberia
Tue, Nov 4 - Fri, Nov 7
LYS
Lyon
ECP
Panama City
$1,461 Roundtrip, found 11 hours ago
$1,461
Roundtrip
found 11 hours ago
Select Iberia flight, departing Tue, Nov 4 from Lyon to Panama City, returning Fri, Nov 7, priced at $1,461 found 11 hours ago

Frequently asked questions

How much does a flight from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Lock in a cheap one-way flight from $514 or cheap return flight from $767 from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP)?
Traveling in November is a great way to save, as it's the cheapest month for flights between LYS and ECP. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from LYS to ECP, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP)?
There aren't any daily nonstop flights departing from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from LYS to ECP?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP)?
To touch down at Northwest Florida Beaches Intl. Airport (ECP) without delays, opt for a flight that leaves from Saint-Exupery Airport (LYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Booking your plane ticket from LYS to ECP just before your journey is generally more expensive. But if you're flexible with your departure times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a LYS to ECP flight and hotel package?
Compared with arranging flights and hotels separately, booking a LYS to ECP flight and hotel package with Expedia could lead to significant savings. Better yet, managing everything in one place will take the stress out of planning your trip. Simply secure your flights and select from our wide range of stays, then tailor your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Saint-Exupery Airport (LYS) to Northwest Florida Beaches Intl. Airport (ECP)?
Typically, you're able to cancel or reschedule your LYS to ECP flight. However, there may be additional charges, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's fees and policies on flight changes, or if you need more details, go to our Customer Service portal.

Travel information

Origin airport
Saint-Exupery
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
Air France, American Airlines, Delta, KLM, United
Roundtrip price
$767
Distance
4791 mi

Book with confidence

Lyon to Panama City Flights

The cheapest times to fly from Lyon to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lyon to Panama City are during the month of November. You can find some of the cheapest flights from Lyon to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lyon to Panama City

Sunday is one of the best days to book for cheap flights from Lyon to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lyon to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lyon to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $514 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lyon to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lyon to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Lyon to Panama City Flights

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*Available to One Key members.