$49 Cheap Flights from Chicago (MDW) to St. Louis (STL)

View $49 flight on Mon, Nov 17, 2025Opens in a new window

Popular airlines from Chicago Midway Airport (MDW) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Chicago to St. Louis (MDW-STL)

Prices were available within the past 7 days and start at $49 for one-way flights and $97 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Sat, Nov 15 - Mon, Nov 17
MDW
Chicago
STL
St. Louis
$97 Roundtrip, found 2 hours ago
$97
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Sat, Nov 15 from Chicago to St. Louis, returning Mon, Nov 17, priced at $97 found 2 hours ago
Southwest Airlines
Tue, Nov 18 - Wed, Nov 19
MDW
Chicago
STL
St. Louis
$101 Roundtrip, found 5 days ago
$101
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Nov 18 from Chicago to St. Louis, returning Wed, Nov 19, priced at $101 found 5 days ago
Southwest Airlines
Sat, Nov 15 - Mon, Nov 17
MDW
Chicago
STL
St. Louis
$107 Roundtrip, found 2 hours ago
$107
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Sat, Nov 15 from Chicago to St. Louis, returning Mon, Nov 17, priced at $107 found 2 hours ago
Southwest Airlines
Sat, Nov 15 - Mon, Nov 17
MDW
Chicago
STL
St. Louis
$112 Roundtrip, found 2 hours ago
$112
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Sat, Nov 15 from Chicago to St. Louis, returning Mon, Nov 17, priced at $112 found 2 hours ago
Southwest Airlines
Sat, Nov 15 - Mon, Nov 17
MDW
Chicago
STL
St. Louis
$117 Roundtrip, found 2 hours ago
$117
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Sat, Nov 15 from Chicago to St. Louis, returning Mon, Nov 17, priced at $117 found 2 hours ago
Southwest Airlines
Sat, Nov 1 - Mon, Nov 3
MDW
Chicago
STL
St. Louis
$117 Roundtrip, found 5 days ago
$117
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Sat, Nov 1 from Chicago to St. Louis, returning Mon, Nov 3, priced at $117 found 5 days ago
Southwest Airlines
Sat, Nov 15 - Mon, Nov 17
MDW
Chicago
STL
St. Louis
$122 Roundtrip, found 2 hours ago
$122
Roundtrip
found 2 hours ago
Select Southwest Airlines flight, departing Sat, Nov 15 from Chicago to St. Louis, returning Mon, Nov 17, priced at $122 found 2 hours ago
Southwest Airlines
Tue, Nov 11 - Fri, Nov 14
MDW
Chicago
STL
St. Louis
$126 Roundtrip, found 1 hour ago
$126
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Tue, Nov 11 from Chicago to St. Louis, returning Fri, Nov 14, priced at $126 found 1 hour ago
Southwest Airlines
Mon, Oct 27 - Thu, Oct 30
MDW
Chicago
STL
St. Louis
$127 Roundtrip, found 1 day ago
$127
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Mon, Oct 27 from Chicago to St. Louis, returning Thu, Oct 30, priced at $127 found 1 day ago
Delta
Sat, Nov 15 - Mon, Nov 17
MDW
Chicago
STL
St. Louis
$137 Roundtrip, found 2 hours ago
$137
Roundtrip
found 2 hours ago
Select Delta flight, departing Sat, Nov 15 from Chicago to St. Louis, returning Mon, Nov 17, priced at $137 found 2 hours ago

Find the cheapest month to fly from Chicago (MDW) to St. Louis (STL)

September is typically the cheapest month to fly

From $77 - $560 per traveler.

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL) cost?
Lock in a cheap one-way flight from $49 or cheap return flight from $97 from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
The cheapest month to fly from MDW to STL is November, when demand is low. Off-peak months are often when you'll find cheap fares for travel between these airports.
Which airlines fly direct from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
You can travel nonstop from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL) on a Southwest Airlines flight.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline that'll fly you from MDW to STL, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
Every day, an average of 3 direct flights take off from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL). Choose the departure date that fits your schedule best.
What are the most popular departure times for flights from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
More people fly between MDW and STL at 8 PM than at any other time of day. Prefer a quieter experience? Try choosing a quieter departure window and you're likely to save on your ticket as well.
What day of the week has the most flights from MDW to STL?
Friday has the most flights from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL). Consider jetting off on this day and you'll have the best chance of finding a departure that fits your plans.
What is the earliest flight from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
Take the earliest flight at around 6:00AM UTC-6, leaving from Midway Intl. Airport (MDW). You'll be in the air for approximately 1h 20m, coming in to land at Lambert-St. Louis Intl. Airport (STL) at approximately 7:20AM UTC-6.
How long does it take to fly from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
It takes about 1 hour and 14 minutes to travel the 250 mi from MDW to STL.
What is the best time to fly from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
To avoid possible delays on the Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL) route, aim to travel before 3 PM. Later flights have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for St. Louis from Midway Intl. Airport (MDW)?
Lambert-St. Louis Intl. Airport (STL) is the only airport in St. Louis with direct flights from Midway Intl. Airport (MDW). Compare the options and discover affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Holding off until right before your break to book your flight from MDW to STL generally means paying more. While it's possible to find some last-minute offers, they aren't always guaranteed. Keep your travel schedule open to maximize your chances of getting a bargain.
Is it cheaper to book a MDW to STL flight and hotel package?
Booking a MDW to STL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our impressive range of stays and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to Lambert-St. Louis Intl. Airport (STL)?
It's usually possible to reschedule or cancel your MDW to STL flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Midway Intl.
Destination airport
Lambert-St. Louis Intl.
Airlines serving
Delta, Frontier Airlines, Southwest Airlines
Roundtrip price
$97
Distance
251 mi
Average flight time
1 hour 11 mins

Book with confidence

Book with confidence

Chicago to St. Louis Flights

The cheapest times to fly from Chicago to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to St. Louis are during the month of November. You can find some of the cheapest flights from Chicago to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to St. Louis

Sunday is one of the best days to book for cheap flights from Chicago to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $49 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to St. Louis Flights

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