$387 Cheap Flights from Mexicali (MXL) to San Diego (SAN)

View $387 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Mexicali, Baja California Norte (MXL-General Rodolfo Sanchez Taboada Intl.) to San Diego Intl. Airport (SAN)

Cheap Flights from Mexicali to San Diego (MXL-SAN)

Prices were available within the past 7 days and start at $387 for one-way flights and $1,516 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Thu, Oct 23 - Sun, Oct 26
MXL
Mexicali
SAN
San Diego
$1,516 Roundtrip, found 6 days ago
$1,516
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Oct 23 from Mexicali to San Diego, returning Sun, Oct 26, priced at $1,516 found 6 days ago
Aeromexico
Thu, Oct 23 - Sun, Oct 26
MXL
Mexicali
SAN
San Diego
$1,746 Roundtrip, found 6 days ago
$1,746
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Oct 23 from Mexicali to San Diego, returning Sun, Oct 26, priced at $1,746 found 6 days ago
Aeromexico
Thu, Oct 23 - Sun, Oct 26
MXL
Mexicali
SAN
San Diego
$1,783 Roundtrip, found 6 days ago
$1,783
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Oct 23 from Mexicali to San Diego, returning Sun, Oct 26, priced at $1,783 found 6 days ago
Aeromexico
Wed, Nov 26 - Sun, Nov 30
MXL
Mexicali
SAN
San Diego
$1,969 Roundtrip, found 6 days ago
$1,969
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Wed, Nov 26 from Mexicali to San Diego, returning Sun, Nov 30, priced at $1,969 found 6 days ago
Aeromexico
Fri, Nov 21 - Thu, Nov 27
MXL
Mexicali
SAN
San Diego
$1,998 Roundtrip, found 2 days ago
$1,998
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Fri, Nov 21 from Mexicali to San Diego, returning Thu, Nov 27, priced at $1,998 found 2 days ago
Aeromexico
Tue, Oct 21 - Sun, Oct 26
MXL
Mexicali
SAN
San Diego
$2,060 Roundtrip, found 2 days ago
$2,060
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Tue, Oct 21 from Mexicali to San Diego, returning Sun, Oct 26, priced at $2,060 found 2 days ago
Aeromexico
Thu, Oct 23 - Sun, Oct 26
MXL
Mexicali
SAN
San Diego
$2,064 Roundtrip, found 6 days ago
$2,064
Roundtrip
found 6 days ago
Select Aeromexico flight, departing Thu, Oct 23 from Mexicali to San Diego, returning Sun, Oct 26, priced at $2,064 found 6 days ago
Aeromexico
Fri, Nov 21 - Thu, Nov 27
MXL
Mexicali
SAN
San Diego
$2,129 Roundtrip, found 2 days ago
$2,129
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Fri, Nov 21 from Mexicali to San Diego, returning Thu, Nov 27, priced at $2,129 found 2 days ago
Aeromexico
Sat, Oct 4 - Mon, Oct 6
MXL
Mexicali
SAN
San Diego
$2,146 Roundtrip, found 4 days ago
$2,146
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Sat, Oct 4 from Mexicali to San Diego, returning Mon, Oct 6, priced at $2,146 found 4 days ago
Aeromexico
Fri, Nov 21 - Thu, Nov 27
MXL
Mexicali
SAN
San Diego
$2,172 Roundtrip, found 2 days ago
$2,172
Roundtrip
found 2 days ago
Select Aeromexico flight, departing Fri, Nov 21 from Mexicali to San Diego, returning Thu, Nov 27, priced at $2,172 found 2 days ago

Frequently asked questions

How much does a flight from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN) cost?
Secure a cheap one-way flight from $387 or cheap return flight from $1,516 from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN)?
October is the least expensive month to fly from MXL to SAN. Planning your trip for the off-season is often the key to landing a great deal.
What is the cheapest airline that flies from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN)?
To find the cheapest airline that'll fly you from MXL to SAN, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN)?
Direct flights from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MXL to SAN?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN)?
Opt for a flight from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN) that leaves before 3 PM to reduce the likelihood of delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN) last-minute?
Last-minute bookings from MXL to SAN are typically more expensive. To lock in the best prices, start looking for flights as soon as possible. That said, if you're flexible with your travel plans, you may find a cheap ticket right before you leave.
Is it cheaper to book a MXL to SAN flight and hotel package?
Compared with arranging flights and hotels separately, booking a MXL to SAN flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one easy place will take the stress out of planning your trip. Just pick your flights and select from our extensive range of hotels, then tailor your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from General Rodolfo Sanchez Taboada Intl. Airport (MXL) to San Diego Intl. Airport (SAN)?
If you reserved your MXL to SAN flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for further details.

Travel information

Travel information

Origin airport
General Rodolfo Sanchez Taboada Intl.
Destination airport
San Diego Intl.
Roundtrip price
$1,515
Distance
113 mi

Book with confidence

Book with confidence

Mexicali to San Diego Flights

The cheapest times to fly from Mexicali to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexicali to San Diego are during the month of October. You can find some of the cheapest flights from Mexicali to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mexicali to San Diego

Sunday is one of the best days to book for cheap flights from Mexicali to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mexicali to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexicali to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $387 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexicali to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexicali to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mexicali to San Diego Flights

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*Available to One Key members.