$440 Cheap Flights from Panama City (PTY) to Mazatlan (MZT)

View $440 flight on Tue, Jan 27, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT)

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Cheap Flights from Panama City to Mazatlan (PTY-MZT)

Prices were available within the past 7 days and start at $440 for one-way flights and $646 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Thu, Aug 7 - Thu, Aug 14
PTY
Panama City
MZT
Mazatlán
$646 Roundtrip, found 4 days ago
$646
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Thu, Aug 7 from Panama City to Mazatlán, returning Thu, Aug 14, priced at $646 found 4 days ago
Aeromexico
Thu, Aug 7 - Thu, Aug 14
PTY
Panama City
MZT
Mazatlán
$757 Roundtrip, found 4 days ago
$757
Roundtrip
found 4 days ago
Select Aeromexico flight, departing Thu, Aug 7 from Panama City to Mazatlán, returning Thu, Aug 14, priced at $757 found 4 days ago
Aeromexico
Mon, Aug 4 - Mon, Aug 11
PTY
Panama City
MZT
Mazatlán
$968 Roundtrip, found 1 day ago
$968
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Mon, Aug 4 from Panama City to Mazatlán, returning Mon, Aug 11, priced at $968 found 1 day ago
Aeromexico
Tue, Aug 5 - Mon, Aug 11
PTY
Panama City
MZT
Mazatlán
$978 Roundtrip, found 1 day ago
$978
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Aug 5 from Panama City to Mazatlán, returning Mon, Aug 11, priced at $978 found 1 day ago
Aeromexico
Wed, Aug 6 - Sat, Aug 9
PTY
Panama City
MZT
Mazatlán
$980 Roundtrip, found 1 day ago
$980
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Wed, Aug 6 from Panama City to Mazatlán, returning Sat, Aug 9, priced at $980 found 1 day ago
Aeromexico
Wed, Aug 6 - Sun, Aug 10
PTY
Panama City
MZT
Mazatlán
$987 Roundtrip, found 1 day ago
$987
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Wed, Aug 6 from Panama City to Mazatlán, returning Sun, Aug 10, priced at $987 found 1 day ago
Aeromexico
Wed, Aug 6 - Mon, Aug 11
PTY
Panama City
MZT
Mazatlán
$991 Roundtrip, found 1 day ago
$991
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Wed, Aug 6 from Panama City to Mazatlán, returning Mon, Aug 11, priced at $991 found 1 day ago
Aeromexico
Tue, Aug 5 - Sun, Aug 10
PTY
Panama City
MZT
Mazatlán
$1,004 Roundtrip, found 1 day ago
$1,004
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Aug 5 from Panama City to Mazatlán, returning Sun, Aug 10, priced at $1,004 found 1 day ago
American Airlines
Thu, Aug 7 - Thu, Aug 14
PTY
Panama City
MZT
Mazatlán
$1,228 Roundtrip, found 4 days ago
$1,228
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Aug 7 from Panama City to Mazatlán, returning Thu, Aug 14, priced at $1,228 found 4 days ago
United
Thu, Aug 7 - Thu, Aug 14
PTY
Panama City
MZT
Mazatlán
$1,433 Roundtrip, found 4 days ago
$1,433
Roundtrip
found 4 days ago
Select United flight, departing Thu, Aug 7 from Panama City to Mazatlán, returning Thu, Aug 14, priced at $1,433 found 4 days ago
Flights from Panama City (PTY) to Mazatlan (MZT)
Origin airport
Tocumen Intl.
Destination airport
General Rafael Buelna Intl.
Airlines serving
Aeromexico
Roundtrip price
$645
Distance
2026 mi

Panama City to Mazatlan Flights

The cheapest times to fly from Panama City to Mazatlan

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Mazatlan are during the month of August. You can find some of the cheapest flights from Panama City to Mazatlan with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Mazatlan

Sunday is one of the best days to book for cheap flights from Panama City to Mazatlan: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Mazatlan

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Mazatlan in 2025. You can also book with separate airlines for your outbound and return journeys, from $440 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Mazatlan flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Mazatlan airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT) cost?
Discover the latest flight deals from PTY to MZT by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PTY to MZT?
The cheapest flights from PTY to MZT are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PTY to MZT?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from PTY to MZT. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT)?
Nonstop flights from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PTY to MZT?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* But this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT)?
To avoid potential delays on the Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT) route, travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT) last-minute?
Waiting until just before your departure to book your flight from PTY to MZT generally means paying more. While you may find some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open to maximize your chances of scoring a bargain.
Is it cheaper to book a PTY to MZT flight and hotel package?
You can save money by booking a PTY to MZT flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. Once you've chosen your preferred accommodations and flights, consider adding extras including activities, tours and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to General Rafael Buelna Intl. Airport (MZT)?
In most cases, you can cancel or reschedule your PTY to MZT flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you need more details, head to our Customer Service portal.

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*Available to One Key members.