$220 Cheap Flights from Roanoke (ROA) to Myrtle Beach (MYR)

View $220 flight on Sat, Oct 18, 2025Opens in a new window

Popular airlines from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR)

Cheap Flights from Roanoke to Myrtle Beach (ROA-MYR)

Prices were available within the past 7 days and start at $220 for one-way flights and $307 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Dec 16 - Tue, Dec 30
ROA
Roanoke
MYR
Myrtle Beach
$307 Roundtrip, found 5 days ago
$307
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Dec 16 from Roanoke to Myrtle Beach, returning Tue, Dec 30, priced at $307 found 5 days ago
Delta
Tue, Dec 2 - Tue, Dec 9
ROA
Roanoke
MYR
Myrtle Beach
$307 Roundtrip, found 12 hours ago
$307
Roundtrip
found 12 hours ago
Select Delta flight, departing Tue, Dec 2 from Roanoke to Myrtle Beach, returning Tue, Dec 9, priced at $307 found 12 hours ago
Delta
Sat, Oct 18 - Tue, Oct 21
ROA
Roanoke
MYR
Myrtle Beach
$317 Roundtrip, found 11 hours ago
$317
Roundtrip
found 11 hours ago
Select Delta flight, departing Sat, Oct 18 from Roanoke to Myrtle Beach, returning Tue, Oct 21, priced at $317 found 11 hours ago
Delta
Thu, Dec 4 - Mon, Dec 8
ROA
Roanoke
MYR
Myrtle Beach
$327 Roundtrip, found 12 hours ago
$327
Roundtrip
found 12 hours ago
Select Delta flight, departing Thu, Dec 4 from Roanoke to Myrtle Beach, returning Mon, Dec 8, priced at $327 found 12 hours ago
American Airlines
Sat, Oct 18 - Tue, Oct 21
ROA
Roanoke
MYR
Myrtle Beach
$337 Roundtrip, found 11 hours ago
$337
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Oct 18 from Roanoke to Myrtle Beach, returning Tue, Oct 21, priced at $337 found 11 hours ago
American Airlines
Sat, Oct 18 - Tue, Oct 21
ROA
Roanoke
MYR
Myrtle Beach
$342 Roundtrip, found 11 hours ago
$342
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Oct 18 from Roanoke to Myrtle Beach, returning Tue, Oct 21, priced at $342 found 11 hours ago
Delta
Sat, Oct 11 - Tue, Oct 14
ROA
Roanoke
MYR
Myrtle Beach
$347 Roundtrip, just found
$347
Roundtrip
just found
Select Delta flight, departing Sat, Oct 11 from Roanoke to Myrtle Beach, returning Tue, Oct 14, priced at $347 just found
Delta
Thu, Dec 4 - Sat, Dec 6
ROA
Roanoke
MYR
Myrtle Beach
$357 Roundtrip, found 12 hours ago
$357
Roundtrip
found 12 hours ago
Select Delta flight, departing Thu, Dec 4 from Roanoke to Myrtle Beach, returning Sat, Dec 6, priced at $357 found 12 hours ago
American Airlines
Sat, Oct 18 - Tue, Oct 21
ROA
Roanoke
MYR
Myrtle Beach
$366 Roundtrip, found 11 hours ago
$366
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Oct 18 from Roanoke to Myrtle Beach, returning Tue, Oct 21, priced at $366 found 11 hours ago
United
Fri, Oct 10 - Mon, Oct 13
ROA
Roanoke
MYR
Myrtle Beach
$1,255 Roundtrip, just found
$1,255
Roundtrip
just found
Select United flight, departing Fri, Oct 10 from Roanoke to Myrtle Beach, returning Mon, Oct 13, priced at $1,255 just found

Find the cheapest month to fly from Roanoke (ROA) to Myrtle Beach (MYR)

May is typically the cheapest month to fly

From $198 - $533 per traveler.

Frequently asked questions

How much does a flight from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR) cost?
Secure a cheap one-way flight from $220 or cheap return flight from $307 from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR)?
December is the most affordable month to fly from ROA to MYR. Traveling during an off-peak travel window is often the key to better flight prices.
What is the cheapest airline that flies from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest ROA to MYR flight.
How many flights per day from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR)?
You'll need to take a flight with a layover if you're traveling from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from ROA to MYR?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR)?
To avoid possible delays on the Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR) route, fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR) last-minute?
Last-minute bookings from ROA to MYR are usually more expensive. To secure the lowest prices, start searching for flights well ahead of time. That being said, if you're flexible with your travel dates, it's possible to land a cheap ticket right before your journey.
Is it cheaper to book a ROA to MYR flight and hotel package?
Compared with arranging hotels and flights separately, booking a ROA to MYR flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place will take the stress out of planning your trip. Simply secure your flights and select from our extensive range of stays, then customize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Roanoke Regional Airport (ROA) to Myrtle Beach Intl. Airport (MYR)?
Generally, it's possible to reschedule or cancel your ROA to MYR flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Roanoke Regional
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$306
Distance
258 mi

Book with confidence

Book with confidence

Roanoke to Myrtle Beach Flights

The cheapest times to fly from Roanoke to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Roanoke to Myrtle Beach are during the month of December. You can find some of the cheapest flights from Roanoke to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Roanoke to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Roanoke to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Roanoke to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Roanoke to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $220 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Roanoke to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Roanoke to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Roanoke to Myrtle Beach Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.