$467 Cheap Flights from Santiago (SCL) to Buffalo (BUF)

View $467 flight on Sun, Mar 8, 2026Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Santiago to Buffalo (SCL-BUF)

Prices were available within the past 7 days and start at $467 for one-way flights and $794 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, Dec 16 - Tue, Dec 23
SCL
Santiago
BUF
Buffalo
$794 Roundtrip, found 17 hours ago
$794
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Dec 16 from Santiago to Buffalo, returning Tue, Dec 23, priced at $794 found 17 hours ago
LATAM Airlines Group
Tue, Dec 16 - Tue, Dec 23
SCL
Santiago
BUF
Buffalo
$799 Roundtrip, found 17 hours ago
$799
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Dec 16 from Santiago to Buffalo, returning Tue, Dec 23, priced at $799 found 17 hours ago
LATAM Airlines Group
Tue, Dec 16 - Tue, Dec 23
SCL
Santiago
BUF
Buffalo
$802 Roundtrip, found 17 hours ago
$802
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Dec 16 from Santiago to Buffalo, returning Tue, Dec 23, priced at $802 found 17 hours ago
LATAM Airlines Group
Tue, Dec 16 - Tue, Dec 23
SCL
Santiago
BUF
Buffalo
$815 Roundtrip, found 17 hours ago
$815
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Dec 16 from Santiago to Buffalo, returning Tue, Dec 23, priced at $815 found 17 hours ago
LATAM Airlines Group
Mon, Dec 15 - Sat, Jan 3
SCL
Santiago
BUF
Buffalo
$833 Roundtrip, found 5 days ago
$833
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 15 from Santiago to Buffalo, returning Sat, Jan 3, priced at $833 found 5 days ago
LATAM Airlines Group
Mon, Dec 15 - Sat, Jan 3
SCL
Santiago
BUF
Buffalo
$843 Roundtrip, found 5 days ago
$843
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 15 from Santiago to Buffalo, returning Sat, Jan 3, priced at $843 found 5 days ago
LATAM Airlines Group
Mon, Dec 15 - Sat, Jan 3
SCL
Santiago
BUF
Buffalo
$858 Roundtrip, found 5 days ago
$858
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 15 from Santiago to Buffalo, returning Sat, Jan 3, priced at $858 found 5 days ago
LATAM Airlines Group
Mon, Dec 15 - Sat, Jan 3
SCL
Santiago
BUF
Buffalo
$859 Roundtrip, found 5 days ago
$859
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 15 from Santiago to Buffalo, returning Sat, Jan 3, priced at $859 found 5 days ago
LATAM Airlines Group
Tue, Dec 16 - Tue, Dec 23
SCL
Santiago
BUF
Buffalo
$954 Roundtrip, found 17 hours ago
$954
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Dec 16 from Santiago to Buffalo, returning Tue, Dec 23, priced at $954 found 17 hours ago
LATAM Airlines Group
Tue, Dec 16 - Tue, Dec 23
SCL
Santiago
BUF
Buffalo
$959 Roundtrip, found 17 hours ago
$959
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Tue, Dec 16 from Santiago to Buffalo, returning Tue, Dec 23, priced at $959 found 17 hours ago

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF) cost?
Lock in a cheap one-way flight from $467 or cheap return flight from $794 from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF)?
The cheapest month to fly from SCL to BUF is December, when demand is low. Off-peak season is often when airlines offer better prices between these airports.
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest SCL to BUF flight.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF)?
You'll need to take a flight with a layover when traveling from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from SCL to BUF?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF)?
To avoid potential delays on the Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF) route, fly before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Booking your flight from SCL to BUF just before your trip is usually more expensive. But if you're flexible with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a SCL to BUF flight and hotel package?
Securing a SCL to BUF flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Select from our extensive range of hotels and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Buffalo Niagara Intl. Airport (BUF)?
If you reserved your SCL to BUF flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

Travel information

Origin airport
Arturo Merino Benitez
Destination airport
Buffalo Niagara Intl.
Airlines serving
LATAM Airlines Group
Roundtrip price
$793
Distance
5297 mi

Book with confidence

Santiago to Buffalo Flights

The cheapest times to fly from Santiago to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Buffalo are during the month of December. You can find some of the cheapest flights from Santiago to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Buffalo

Sunday is one of the best days to book for cheap flights from Santiago to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $467 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santiago to Buffalo Flights

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*Available to One Key members.