Cheap Alaska Airlines flights St. Louis (STL) to San Diego (SAN)

Grab affordable return Alaska Airlines flights from $248 from STL to SAN by filtering your results from “Price (lowest to highest)” on Expedia. Or search for deals for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the least expensive months to jet away to San Diego with Alaska Airlines. You could also find excellent prices on one-way and round-trip tickets in November.

Look for affordable Alaska Airlines flights from Lambert-St. Louis Intl. Airport (STL) to San Diego Intl. Airport (SAN) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the best day of the week to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use our “Nonstop” filter when looking for direct Alaska Airlines flights from STL to SAN. It’s also a good way to compare other carriers offering the same nonstop journey.

To find the earliest departures from STL to SAN with Alaska Airlines, filter your results by “Morning” and “Early Morning.” Choosing an early flight generally means you’ll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Catch an Alaska Airlines flight from Lambert-St. Louis Intl. Airport (STL) to San Diego, and you’re most likely to touch down at San Diego Intl. Airport (SAN). This is the airline’s main hub in this destination.

With an excellent in-flight experience and top-tier customer service, Alaska Airlines is a popular option for many passengers heading from STL to SAN. Also, if you’re a Mileage Plan and One Key™ member booking with Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Depending on the type of ticket you purchased, a fee may apply if you cancel or reschedule your flight more than 24 hours after it has been confirmed. To secure flexible plane tickets, select our “No cancel fee” or “Changes included” filter while searching for flights. For more information on changing or canceling your reservation, go to “Trips,” select your flight and tick “Manage Booking.”