$149 Cheap American Airlines flights Milwaukee (MKE) to Charleston (CRW)

Scoring cheap one-way American Airlines flights from MKE to CRW from $149 on Expedia is a cinch — just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares from $248 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from General Mitchell Intl. Airport (MKE) to Yeager Airport (CRW) one to three months before your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and itinerary, the best day of the week to book a domestic flight is generally Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to find the earliest departures from MKE to CRW. Heading off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.