$100 Cheap American Airlines flights Cleveland (CLE) to Myrtle Beach (MYR)

Apply the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines return flights from $218 from CLE to MYR. Affordable one-way fares from $100 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Hopkins Intl. Airport (CLE) to Myrtle Beach Intl. Airport (MYR) one to three months prior to your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the ideal day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Find American Airlines's earliest flights from CLE to MYR by checking the "Morning" and "Early Morning" filters. Not only will you get to where you're going sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.