$100 Cheap American Airlines flights Indianapolis (IND) to San Diego (SAN)

Make use of the “Price (lowest to highest)” filter on Expedia to find cheap American Airlines round-trip flights from $199 from IND to SAN. Affordable one-way tickets from $100 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to jet off to San Diego with American Airlines. You could also find great prices on return and one-way tickets in November.

Search for affordable American Airlines flights from Indianapolis Intl. Airport (IND) to San Diego Intl. Airport (SAN) one to three months ahead of your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the best day to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use the “Nonstop” filter when looking for direct American Airlines flights from IND to SAN. It’s also a great way to compare other carriers offering the same direct route.

Sort your results by “Morning” and “Early Morning” to browse the earliest departures from IND to SAN. Jetting off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Diego Intl. Airport (SAN) is the main San Diego gateway for American Airlines flights from Indianapolis Intl. Airport (IND).

Changes are often free within 24 hours of booking, but your airline may charge a fee after that time. For further information about altering your flights, go to your “Trips,” select your flight and click on “Manage Booking.” If you want the freedom to update your itinerary without additional costs, check the “Changes included” or “No cancel fee” filter when organizing your next trip.