$144 Cheap American Airlines flights Memphis (MEM) to San Diego (SAN)

Finding cheap one-way American Airlines flights from MEM to SAN from $144 on Expedia is simple — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly round-trip fares from $287 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for one-way or round-trip flights to San Diego in January or November. You could find a cheap fare with American Airlines during these quieter months.

For cheap American Airlines fares from Memphis Intl. Airport (MEM) to San Diego Intl. Airport (SAN), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect the overall price. Sunday is typically the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To figure out if there’s a direct journey from MEM to SAN with American Airlines or another carrier, check the “Nonstop” box when browsing for tickets.

To find the earliest departures from MEM to SAN with American Airlines, filter your search by “Morning” and “Early Morning.” Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Board an American Airlines flight from Memphis Intl. Airport (MEM) to San Diego, and you’ll most likely touch down at San Diego Intl. Airport (SAN). This is the airline’s primary hub here.

It’s usually possible to cancel or reschedule your flight, although additional fees may apply if you booked more than 24 hours ago. Need flexible options? Make use of our “No cancel fee” or “Changes included” filter to find flights that won’t penalize you if you have to revise your plans. To update your booking, head to “Trips,” select your flight and click on “Manage Booking” for more details.