$116 Cheap American Airlines flights Myrtle Beach (MYR) to Boston (BOS)

Finding cheap one-way American Airlines flights from MYR to BOS from $116 on Expedia is simple --- just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares from $231 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Myrtle Beach Intl. Airport (MYR) to Logan Intl. Airport (BOS) one to three months before your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the best day to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Morning" and "Early Morning" to find the earliest departures from MYR to BOS. Taking off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.