$253 Cheap American Airlines flights Fayetteville (XNA) to San Francisco (SFO)

Scoring cheap one-way American Airlines flights from XNA to SFO from $253 on Expedia is a breeze — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $283 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from Northwest Arkansas Regional Airport (XNA) to San Francisco Intl. Airport (SFO) one to three months prior to your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the best day of the week to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Search American Airlines's earliest flights from XNA to SFO by selecting our "Early Morning" and "Morning" filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.