$80 Cheap American Airlines flights San Francisco (SFO) to San Diego (SAN)

Use the “Price (lowest to highest)” filter on Expedia to find cheap American Airlines return flights from $159 from SFO to SAN. Affordable one-way options from $80 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to get away to San Diego with American Airlines. You could also find fantastic deals on return and one-way fares in November.

To find cheap American Airlines fares from San Francisco Intl. Airport (SFO) to San Diego Intl. Airport (SAN), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact what you pay. Sunday tends to be the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To see if there’s a direct route from SFO to SAN with American Airlines or any other airlines, check the “Nonstop” filter when looking for tickets.

Filter your results by “Early Morning” and “Morning” to see the earliest departures from SFO to SAN. Jetting off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

San Diego Intl. Airport (SAN) is the primary San Diego gateway for American Airlines flights from San Francisco Intl. Airport (SFO).

Depending on the type of ticket you purchased, a fee typically applies if you cancel or reschedule your flight more than 24 hours after it’s confirmed. To secure flexible plane tickets, select our “No cancel fee” or “Changes included” filter while looking for flights. For more information on canceling or changing your reservation, go to “Trips,” select your flight and tick “Manage Booking.”