$102 Cheap Delta flights Knoxville (TYS) to Myrtle Beach (MYR)

Landing cheap one-way Delta Air Lines flights from TYS to MYR from $102 on Expedia is easy — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $203 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap Delta Air Lines fares from McGhee Tyson Airport (TYS) to Myrtle Beach Intl. Airport (MYR), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the overall cost. Sunday is typically the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your flight on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from TYS to MYR with Delta Air Lines, filter your search by "Early Morning" and "Morning." Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Delta Air Lines makes traveling from TYS to MYR enjoyable with a rewarding loyalty program and an excellent in-flight experience. You also have the chance to earn points with Delta SkyMiles. Make sure you sign up to our free One Key™ rewards program to earn OneKeyCash™*, which can be redeemed on future bookings.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.