$195 Cheap Delta flights Roanoke (ROA) to San Diego (SAN)

Use the "Price (lowest to highest)" filter on Expedia to look for cheap Delta Air Lines return flights from $344 from ROA to SAN. Affordable one-way tickets from $195 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your travel date to find cheap fares on Delta Air Lines flights from Roanoke Regional Airport (ROA) to San Diego Intl. Airport (SAN). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to find the earliest flights from ROA to SAN. Taking off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Flying from ROA to SAN with Delta Air Lines means enjoying a host of perks, such as a rewarding loyalty program and an excellent in-flight experience. Plus, when you book through Expedia, One Key™ members can earn OneKeyCash™* to redeem on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.