$133 Cheap Delta flights Medford (MFR) to San Francisco (SFO)

Finding cheap one-way Delta Air Lines flights from MFR to SFO from $133 on Expedia is easy — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly return fares from $258 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or round-trip flights to San Francisco in February or April. You could find a cheap fare with Delta Air Lines during these off-peak months.

For cheap Delta Air Lines fares from Rogue Valley Intl. Airport (MFR) to San Francisco Intl. Airport (SFO), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the cost. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your flight on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To figure out if there’s a direct trip from MFR to SFO with Delta Air Lines or any other airlines, check the “Nonstop” box when browsing for tickets.

To find the earliest departures from MFR to SFO with Delta Air Lines, filter your results by “Early Morning” and “Morning.” Booking an early flight usually means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Delta Air Lines flights from Rogue Valley Intl. Airport (MFR) to San Francisco come in to San Francisco Intl. Airport (SFO). This is the main entry point to this city.

Jetting off from MFR to SFO with Delta Air Lines comes with a variety of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when booking through Expedia, One Key™ members can earn OneKeyCash™* to spend on select future travel purchases. That’s in addition to the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Changes are often free within 24 hours of making your booking, but your airline may charge you after that. For further details about modifying your flights, head to your “Trips,” select your flight and click on “Manage Booking.” If you want the freedom to update your itinerary without additional charges, apply the “No cancel fee” or “Changes included” filter when planning your next escape.