$158 Cheap Frontier Airlines flights Knoxville (TYS) to San Diego (SAN)

View $158 flight on Thu, Nov 6, 2025Opens in a new window

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$158 Cheap Frontier Airlines flights Knoxville (TYS) to San Diego (SAN)

Prices were available within the past 7 days and start at $158 for one-way flights and $316 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Aug 7 - Thu, Aug 28
TYS
Knoxville
SAN
San Diego
$316 Roundtrip, found 4 hours ago
$316
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Thu, Aug 7 from Knoxville to San Diego, returning Thu, Aug 28, priced at $316 found 4 hours ago
Frontier Airlines
Sun, Aug 10 - Mon, Aug 25
TYS
Knoxville
SAN
San Diego
$321 Roundtrip, found 4 hours ago
$321
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sun, Aug 10 from Knoxville to San Diego, returning Mon, Aug 25, priced at $321 found 4 hours ago
Flights from Knoxville (TYS) to San Diego (SAN)
Origin airport
McGhee Tyson
Destination airport
San Diego Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, United
Popular airline
Alaska Airlines
Distance
1898 mi

Frequently asked questions

How much is a Frontier Airlines flight from McGhee Tyson Airport (TYS) to San Diego Intl. Airport (SAN)?
Grab affordable return Frontier Airlines flights from $316 from TYS to SAN by organizing your results from "Price (lowest to highest)" on Expedia. Or search for options from $158 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from TYS to SAN with Frontier Airlines?
Frontier Airlines flights to San Diego are usually cheaper in the quieter months of January and November. Whether you're after a one-way or round-trip ticket, you could score a better deal then.
What is the cheapest time to book flights from McGhee Tyson Airport (TYS) to San Diego Intl. Airport (SAN) with Frontier Airlines?
Begin your search one to three months ahead of your departure date to score cheaper fares on Frontier Airlines flights from McGhee Tyson Airport (TYS) to San Diego Intl. Airport (SAN). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Frontier Airlines fly nonstop from McGhee Tyson Airport (TYS) to San Diego Intl. Airport (SAN)?
To figure out if there's a direct trip from TYS to SAN with Frontier Airlines or any other carriers, check the "Nonstop" box when looking for tickets.
What is the earliest Frontier Airlines flight from TYS to SAN?
Find Frontier Airlines's earliest flights from TYS to SAN by selecting our "Morning" and "Early Morning" filters. Not only will you arrive at your destination sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Frontier Airlines fly into in San Diego?
Frontier Airlines flights from McGhee Tyson Airport (TYS) to San Diego come in to San Diego Intl. Airport (SAN). This is the main entry point here.
Why fly with Frontier Airlines from TYS to SAN?
Offering a rewarding loyalty program, Frontier Airlines is a popular choice for many travelers departing from TYS to SAN. Plus, as a Frontier Miles and One Key™ member booking through Expedia, you can earn OneKeyCash™* on eligible flights along with your airline miles.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
Can I change or cancel my Frontier Airlines flight from McGhee Tyson Airport (TYS) to San Diego Intl. Airport (SAN)?
Changes are typically free within 24 hours of making a booking, but your airline may charge a fee after that. For further information about altering your flights, check out your "Trips," select your flight and click on "Manage Booking." If you'd like the freedom to change your plans without extra charges, apply the "No cancel fee" or "Changes included" filter when planning your trip.

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*Available to One Key members.