$159 Cheap United flights Raleigh (RDU) to Knoxville (TYS)

Finding cheap one-way United Airlines flights from RDU to TYS from $159 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Or check out our affordable return fares from $312 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap United Airlines fares from Raleigh - Durham Intl. Airport (RDU) to McGhee Tyson Airport (TYS), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect the price you pay. Sunday is generally the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from RDU to TYS with United Airlines, sort your results by "Morning" and "Early Morning." Booking an early flight usually means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

A rewarding loyalty program and the ability to collect points through United Mileage Plus are the start of the reasons to jet off from RDU to TYS with United Airlines. Plus, when you sign up to Expedia's free One Key™ program, you can receive OneKeyCash™* on top of any airline loyalty program earnings. It's yours to use wherever your next trip takes you.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.