$100 Cheap Flights from Buffalo (BUF) to Myrtle Beach (MYR)

View $100 flight on Sat, Sep 6, 2025Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from Buffalo to Myrtle Beach (BUF-MYR)

Prices were available within the past 7 days and start at $100 for one-way flights and $199 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Sep 4 - Sat, Sep 6
BUF
Buffalo
MYR
Myrtle Beach
$199 Roundtrip, found 2 days ago
$199
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep 4 from Buffalo to Myrtle Beach, returning Sat, Sep 6, priced at $199 found 2 days ago
American Airlines
Fri, Oct 31 - Tue, Nov 4
BUF
Buffalo
MYR
Myrtle Beach
$218 Roundtrip, found 1 day ago
$218
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 31 from Buffalo to Myrtle Beach, returning Tue, Nov 4, priced at $218 found 1 day ago
American Airlines
Fri, Oct 31 - Tue, Nov 4
BUF
Buffalo
MYR
Myrtle Beach
$219 Roundtrip, found 1 day ago
$219
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 31 from Buffalo to Myrtle Beach, returning Tue, Nov 4, priced at $219 found 1 day ago
United
Sat, Sep 6 - Sat, Sep 13
BUF
Buffalo
MYR
Myrtle Beach
$225 Roundtrip, found 1 hour ago
$225
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Sep 6 from Buffalo to Myrtle Beach, returning Sat, Sep 13, priced at $225 found 1 hour ago
American Airlines
Fri, Oct 31 - Mon, Nov 3
BUF
Buffalo
MYR
Myrtle Beach
$226 Roundtrip, found 1 day ago
$226
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 31 from Buffalo to Myrtle Beach, returning Mon, Nov 3, priced at $226 found 1 day ago
Southwest Airlines
Sat, Aug 30 - Wed, Sep 3
BUF
Buffalo
MYR
Myrtle Beach
$228 Roundtrip, found 21 hours ago
$228
Roundtrip
found 21 hours ago
Select Southwest Airlines flight, departing Sat, Aug 30 from Buffalo to Myrtle Beach, returning Wed, Sep 3, priced at $228 found 21 hours ago
American Airlines
Sat, Sep 6 - Sat, Sep 13
BUF
Buffalo
MYR
Myrtle Beach
$228 Roundtrip, found 1 hour ago
$228
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Sep 6 from Buffalo to Myrtle Beach, returning Sat, Sep 13, priced at $228 found 1 hour ago
United
Sat, Sep 6 - Sat, Sep 13
BUF
Buffalo
MYR
Myrtle Beach
$230 Roundtrip, found 1 hour ago
$230
Roundtrip
found 1 hour ago
Select United flight, departing Sat, Sep 6 from Buffalo to Myrtle Beach, returning Sat, Sep 13, priced at $230 found 1 hour ago
Delta
Sat, Aug 30 - Wed, Sep 3
BUF
Buffalo
MYR
Myrtle Beach
$231 Roundtrip, found 21 hours ago
$231
Roundtrip
found 21 hours ago
Select Delta flight, departing Sat, Aug 30 from Buffalo to Myrtle Beach, returning Wed, Sep 3, priced at $231 found 21 hours ago
United
Sun, Aug 31 - Thu, Sep 11
BUF
Buffalo
MYR
Myrtle Beach
$233 Roundtrip, found 2 days ago
$233
Roundtrip
found 2 days ago
Select United flight, departing Sun, Aug 31 from Buffalo to Myrtle Beach, returning Thu, Sep 11, priced at $233 found 2 days ago

Find the cheapest month to fly from Buffalo (BUF) to Myrtle Beach (MYR)

August is typically the cheapest month to fly

From $160 - $576 per traveler.

Graph displaying average flight prices per month

Alternative airports near Myrtle Beach

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Myrtle Beach Intl. Airport MYR. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $225
MYR
Myrtle Beach Intl. Airport
CheapestClosest
Average driving time to city center6 min
Flights from $225
Flights from Buffalo (BUF) to Myrtle Beach (MYR)
Origin airport
Buffalo Niagara Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$198
Distance
639 mi

Buffalo to Myrtle Beach Flights

The cheapest times to fly from Buffalo to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Myrtle Beach are during the month of September. You can find some of the cheapest flights from Buffalo to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Buffalo to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $100 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) cost?
Secure a cheap one-way flight from $100 or cheap return flight from $199 from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
Traveling in September is a good way to save, as it's the cheapest month for flights between BUF and MYR. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll fly you from BUF to MYR. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
Nonstop flights from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from BUF to MYR?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
Choose a flight from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR) last-minute?
Waiting until just before your trip to book a ticket from BUF to MYR generally means paying more. While it's possible to find some last-minute deals, they're not always guaranteed. Allow some flexibility in your schedule for the best chance of landing a bargain.
Is it cheaper to book a BUF to MYR flight and hotel package?
You'll generally save money by securing a BUF to MYR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After selecting your preferred accommodations and flights, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)?
If you booked your BUF to MYR flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

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*Available to One Key members.