$214 Cheap Flights from Lexington (LEX) to San Diego (SAN)

View $214 flight on Sat, Nov 8, 2025Opens in a new window

Popular airlines from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN)

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Cheap Flights from Lexington to San Diego (LEX-SAN)

Prices were available within the past 7 days and start at $214 for one-way flights and $217 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Sep 23 - Sat, Sep 27
LEX
Lexington
SAN
San Diego
$217 Roundtrip, just found
$217
Roundtrip
just found
Select American Airlines flight, departing Tue, Sep 23 from Lexington to San Diego, returning Sat, Sep 27, priced at $217 just found
American Airlines
Thu, Sep 4 - Sat, Sep 6
LEX
Lexington
SAN
San Diego
$222 Roundtrip, found 12 hours ago
$222
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Thu, Sep 4 from Lexington to San Diego, returning Sat, Sep 6, priced at $222 found 12 hours ago
American Airlines
Sat, Oct 25 - Fri, Oct 31
LEX
Lexington
SAN
San Diego
$253 Roundtrip, just found
$253
Roundtrip
just found
Select American Airlines flight, departing Sat, Oct 25 from Lexington to San Diego, returning Fri, Oct 31, priced at $253 just found
American Airlines
Tue, Sep 23 - Sat, Sep 27
LEX
Lexington
SAN
San Diego
$258 Roundtrip, just found
$258
Roundtrip
just found
Select American Airlines flight, departing Tue, Sep 23 from Lexington to San Diego, returning Sat, Sep 27, priced at $258 just found
Delta
Tue, Sep 23 - Sat, Sep 27
LEX
Lexington
SAN
San Diego
$277 Roundtrip, just found
$277
Roundtrip
just found
Select Delta flight, departing Tue, Sep 23 from Lexington to San Diego, returning Sat, Sep 27, priced at $277 just found
United
Tue, Sep 23 - Sat, Sep 27
LEX
Lexington
SAN
San Diego
$277 Roundtrip, just found
$277
Roundtrip
just found
Select United flight, departing Tue, Sep 23 from Lexington to San Diego, returning Sat, Sep 27, priced at $277 just found
American Airlines
Wed, Dec 17 - Mon, Dec 29
LEX
Lexington
SAN
San Diego
$278 Roundtrip, found 19 hours ago
$278
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Wed, Dec 17 from Lexington to San Diego, returning Mon, Dec 29, priced at $278 found 19 hours ago
United
Tue, Sep 23 - Sat, Sep 27
LEX
Lexington
SAN
San Diego
$282 Roundtrip, just found
$282
Roundtrip
just found
Select United flight, departing Tue, Sep 23 from Lexington to San Diego, returning Sat, Sep 27, priced at $282 just found
American Airlines
Thu, Sep 4 - Sat, Sep 6
LEX
Lexington
SAN
San Diego
$283 Roundtrip, found 12 hours ago
$283
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Thu, Sep 4 from Lexington to San Diego, returning Sat, Sep 6, priced at $283 found 12 hours ago
Alaska Airlines
Sat, Nov 1 - Sat, Nov 8
LEX
Lexington
SAN
San Diego
$307 Roundtrip, found 22 hours ago
$307
Roundtrip
found 22 hours ago
Select Alaska Airlines flight, departing Sat, Nov 1 from Lexington to San Diego, returning Sat, Nov 8, priced at $307 found 22 hours ago

Find the cheapest month to fly from Lexington (LEX) to San Diego (SAN)

August is typically the cheapest month to fly

From $216 - $659 per traveler.

Graph displaying average flight prices per month

Alternative airports near San Diego

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to General Abelardo L. Rodriguez Intl. TIJ. Average driving time to city center is 26 minutes. Flights from $759
TIJ
General Abelardo L. Rodriguez Intl.
Average driving time to city center26 min
Flights from $759
Flights from Lexington (LEX) to San Diego (SAN)
Origin airport
Blue Grass
Destination airport
San Diego Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, United
Roundtrip price
$216
Distance
1862 mi

Lexington to San Diego Flights

The cheapest times to fly from Lexington to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lexington to San Diego are during the month of September. You can find some of the cheapest flights from Lexington to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Lexington to San Diego

Sunday is one of the best days to book for cheap flights from Lexington to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Lexington to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lexington to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $214 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lexington to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lexington to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN) cost?
Secure a cheap one-way flight from $214 or cheap return flight from $217 from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN)?
Traveling in September can help you save, as it's the cheapest month for flights between LEX and SAN. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN)?
To find the cheapest airline flying from LEX to SAN, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN)?
There aren't any daily nonstop flights from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN). But you can book flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from LEX to SAN?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN)?
To land at San Diego Intl. Airport (SAN) on schedule, book a flight that leaves from Blue Grass Airport (LEX) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN) last-minute?
Holding off until right before your break to book a flight from LEX to SAN generally means paying more. While you might find some last-minute deals, there's no guarantee. Be flexible with your travel plans for a better chance of scoring a bargain.
Is it cheaper to book a LEX to SAN flight and hotel package?
Compared with arranging hotels and flights separately, booking a LEX to SAN flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place takes the hassle out of planning your trip. Just pick your flights and choose from our extensive range of stays, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Blue Grass Airport (LEX) to San Diego Intl. Airport (SAN)?
In most cases, you can cancel or modify your LEX to SAN flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you want more information, go to our Customer Service portal.

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*Available to One Key members.