$199 Cheap Flights from Amarillo (AMA) to Knoxville (TYS)

View $199 flight on Sun, Nov 23, 2025Opens in a new window

Popular airlines from Amarillo, TX (AMA-Rick Husband Amarillo Intl.) to McGhee Tyson Airport (TYS)

Cheap Flights from Amarillo to Knoxville (AMA-TYS)

Prices were available within the past 7 days and start at $199 for one-way flights and $353 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jun 24 - Tue, Jun 30
AMA
Amarillo
TYS
Knoxville
$353 Roundtrip, found 20 hours ago
$353
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Amarillo to Knoxville, returning Tue, Jun 30, priced at $353 found 20 hours ago
American Airlines
Wed, Jun 24 - Tue, Jun 30
AMA
Amarillo
TYS
Knoxville
$380 Roundtrip, found 20 hours ago
$380
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jun 24 from Amarillo to Knoxville, returning Tue, Jun 30, priced at $380 found 20 hours ago
American Airlines
Sun, Nov 23 - Sat, Dec 6
AMA
Amarillo
TYS
Knoxville
$393 Roundtrip, just found
$393
Roundtrip
just found
Select American Airlines flight, departing Sun, Nov 23 from Amarillo to Knoxville, returning Sat, Dec 6, priced at $393 just found
American Airlines
Sun, Nov 23 - Sun, Dec 7
AMA
Amarillo
TYS
Knoxville
$397 Roundtrip, found 1 day ago
$397
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Nov 23 from Amarillo to Knoxville, returning Sun, Dec 7, priced at $397 found 1 day ago
United
Sat, Oct 18 - Sat, Oct 25
AMA
Amarillo
TYS
Knoxville
$407 Roundtrip, found 4 days ago
$407
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 18 from Amarillo to Knoxville, returning Sat, Oct 25, priced at $407 found 4 days ago
United
Sat, Oct 18 - Sat, Oct 25
AMA
Amarillo
TYS
Knoxville
$412 Roundtrip, found 4 days ago
$412
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 18 from Amarillo to Knoxville, returning Sat, Oct 25, priced at $412 found 4 days ago
American Airlines
Thu, Jun 25 - Tue, Jun 30
AMA
Amarillo
TYS
Knoxville
$415 Roundtrip, found 20 hours ago
$415
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Thu, Jun 25 from Amarillo to Knoxville, returning Tue, Jun 30, priced at $415 found 20 hours ago
United
Sat, Oct 18 - Sat, Oct 25
AMA
Amarillo
TYS
Knoxville
$417 Roundtrip, found 4 days ago
$417
Roundtrip
found 4 days ago
Select United flight, departing Sat, Oct 18 from Amarillo to Knoxville, returning Sat, Oct 25, priced at $417 found 4 days ago
United
Fri, Oct 31 - Sat, Nov 15
AMA
Amarillo
TYS
Knoxville
$423 Roundtrip, found 6 days ago
$423
Roundtrip
found 6 days ago
Select United flight, departing Fri, Oct 31 from Amarillo to Knoxville, returning Sat, Nov 15, priced at $423 found 6 days ago
Southwest Airlines
Mon, May 18 - Fri, May 22
AMA
Amarillo
TYS
Knoxville
$467 Roundtrip, found 3 days ago
$467
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Mon, May 18 from Amarillo to Knoxville, returning Fri, May 22, priced at $467 found 3 days ago

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $450
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $450
Flights from Amarillo (AMA) to Knoxville (TYS)
Origin airport
Rick Husband Amarillo Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, United
Roundtrip price
$352
Distance
995 mi

Amarillo to Knoxville Flights

The cheapest times to fly from Amarillo to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Amarillo to Knoxville are during the month of June. You can find some of the cheapest flights from Amarillo to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Amarillo to Knoxville

Sunday is one of the best days to book for cheap flights from Amarillo to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Amarillo to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Amarillo to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $199 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Amarillo to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Amarillo to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS) cost?
Secure a cheap one-way flight from $199 or cheap return flight from $353 from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS)?
Flying in June is a great way to save, as it's the cheapest month for flights between AMA and TYS. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll take you from AMA to TYS. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS)?
There are no daily direct flights departing from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from AMA to TYS?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on various factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS)?
To avoid possible delays on the Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS) route, aim to travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS) last-minute?
Booking your ticket from AMA to TYS right before your getaway is generally more expensive. But if you're flexible with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book an AMA to TYS flight and hotel package?
Compared with arranging flights and hotels separately, booking an AMA to TYS flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place will take the hassle out of travel planning. Just pick your flights and choose from our extensive range of stays, then customize your trip with extras like tours and car rentals.
Can I cancel or change the date of my flight from Rick Husband Amarillo Intl. Airport (AMA) to McGhee Tyson Airport (TYS)?
Usually, it's possible to cancel or reschedule your AMA to TYS flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.