$126 Cheap Flights from Buffalo (BUF) to Panama City (ECP)

View $126 flight on Wed, Dec 17, 2025Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Buffalo to Panama City (BUF-ECP)

Prices were available within the past 7 days and start at $126 for one-way flights and $251 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Nov 19 - Tue, Dec 9
BUF
Buffalo
ECP
Panama City
$251 Roundtrip, found 20 hours ago
$251
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Nov 19 from Buffalo to Panama City, returning Tue, Dec 9, priced at $251 found 20 hours ago
American Airlines
Wed, Dec 10 - Mon, Dec 15
BUF
Buffalo
ECP
Panama City
$268 Roundtrip, found 4 hours ago
$268
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Dec 10 from Buffalo to Panama City, returning Mon, Dec 15, priced at $268 found 4 hours ago
Southwest Airlines
Wed, Dec 10 - Mon, Dec 15
BUF
Buffalo
ECP
Panama City
$273 Roundtrip, found 4 hours ago
$273
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Wed, Dec 10 from Buffalo to Panama City, returning Mon, Dec 15, priced at $273 found 4 hours ago
Southwest Airlines
Wed, Dec 10 - Mon, Dec 15
BUF
Buffalo
ECP
Panama City
$278 Roundtrip, found 4 hours ago
$278
Roundtrip
found 4 hours ago
Select Southwest Airlines flight, departing Wed, Dec 10 from Buffalo to Panama City, returning Mon, Dec 15, priced at $278 found 4 hours ago
Delta
Wed, Nov 19 - Mon, Nov 24
BUF
Buffalo
ECP
Panama City
$283 Roundtrip, found 20 hours ago
$283
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Nov 19 from Buffalo to Panama City, returning Mon, Nov 24, priced at $283 found 20 hours ago
Delta
Wed, Nov 19 - Sat, Dec 6
BUF
Buffalo
ECP
Panama City
$285 Roundtrip, found 20 hours ago
$285
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Nov 19 from Buffalo to Panama City, returning Sat, Dec 6, priced at $285 found 20 hours ago
American Airlines
Thu, Dec 11 - Mon, Dec 15
BUF
Buffalo
ECP
Panama City
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 11 from Buffalo to Panama City, returning Mon, Dec 15, priced at $287 found 1 day ago
Delta
Wed, Feb 11 - Wed, Feb 18
BUF
Buffalo
ECP
Panama City
$292 Roundtrip, found 20 hours ago
$292
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Feb 11 from Buffalo to Panama City, returning Wed, Feb 18, priced at $292 found 20 hours ago
Delta
Tue, Oct 28 - Sat, Nov 8
BUF
Buffalo
ECP
Panama City
$298 Roundtrip, found 2 days ago
$298
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Oct 28 from Buffalo to Panama City, returning Sat, Nov 8, priced at $298 found 2 days ago
United
Tue, Mar 3 - Sat, Mar 14
BUF
Buffalo
ECP
Panama City
$437 Roundtrip, found 2 days ago
$437
Roundtrip
found 2 days ago
Select United flight, departing Tue, Mar 3 from Buffalo to Panama City, returning Sat, Mar 14, priced at $437 found 2 days ago

Find the cheapest month to fly from Buffalo (BUF) to Panama City (ECP)

August is typically the cheapest month to fly

From $216 - $535 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $381
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $381

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Get a cheap one-way flight from $126 or cheap return flight from $251 from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP)?
Traveling in November is a good way to save, as it's the cheapest month for flights between BUF and ECP. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from BUF to ECP. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP)?
You'll need to hop on a flight with a layover if you're traveling from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from BUF to ECP?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP)?
To touch down at Northwest Florida Beaches Intl. Airport (ECP) on time, book a flight that takes off from Buffalo Niagara Intl. Airport (BUF) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Booking your flight from BUF to ECP shortly before your journey is typically more expensive. However, if you're flexible with your departure dates and times, you could land a cheap last-minute fare.
Is it cheaper to book a BUF to ECP flight and hotel package?
Booking a BUF to ECP flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of stays and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Northwest Florida Beaches Intl. Airport (ECP)?
You can usually cancel or reschedule your BUF to ECP flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$250
Distance
952 mi

Book with confidence

Book with confidence

Buffalo to Panama City Flights

The cheapest times to fly from Buffalo to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Panama City are during the month of November. You can find some of the cheapest flights from Buffalo to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Panama City

Sunday is one of the best days to book for cheap flights from Buffalo to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $126 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to Panama City Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.