Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Myrtle Beach Intl. Airport (MYR)
American AirlinesAmerican Airlines
DeltaDelta
Southwest AirlinesSouthwest Airlines
UnitedUnited
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 30% on select hotels after you book a flight*
Cheap Flights from Buffalo to Myrtle Beach (BUF-MYR)
Prices were available within the past 7 days and start at $129 for one-way flights and $251 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Frequently asked questions
Travel information
Travel information
Origin airport | Buffalo Niagara Intl. |
Destination airport | Myrtle Beach Intl. |
Airlines serving | American Airlines, Delta, Southwest Airlines, United |
Roundtrip price | $251 |
Distance | 639 mi |
Book with confidence
Book with confidence
The cheapest times to fly from Buffalo to Myrtle Beach
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Myrtle Beach are during the month of June. You can find some of the cheapest flights from Buffalo to Myrtle Beach with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Buffalo to Myrtle Beach
Sunday is one of the best days to book for cheap flights from Buffalo to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Buffalo to Myrtle Beach
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $129 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
Be inspired and discover more with Expedia
Be inspired and discover more with Expedia
Flights
- Flights from Elmira - Corning Regional
- Flights from Venango Regional
- Flights from Greater Rochester Intl.
- Flights from Bradford Regional
- Flights from Erie Intl.
- Flights from Chautauqua County
- Flights from Tompkins Regional
- Flights from Cattaraugus County
- Flights from DuBois Regional
- Flights from Niagara Falls Intl.
- Flights to Nashville
- Flights to San Francisco
- Flights to Orlando
- Flights to Miami
- Flights to San Diego
- Flights to New Orleans
- Flights to Chicago
- Flights to Washington
- Flights to Boston
- Flights to Fort Lauderdale
- Flights to New York
- Flights to Houston
- Flights to Los Angeles
- Flights to Honolulu
- Flights to Gatlinburg
- Flights to San Antonio
- Flights to Atlanta
- Flights to Key West
- Flights to Las Vegas
- Flights to Pigeon Forge
- JetBlue Airways Buffalo (BUF) to Fort Lauderdale (FLL) flights
- JetBlue Airways Buffalo (BUF) to Phoenix (PHX) flights
- JetBlue Airways Buffalo (BUF) to Los Angeles (LAX) flights
- JetBlue Airways Buffalo (BUF) to New York (JFK) flights
- Delta Buffalo (BUF) to Charlotte (CLT) flights
- Spirit Airlines Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR) flights
- American Airlines Syracuse (SYR) to Myrtle Beach (MYR) flights
- Spirit Airlines Boston (BOS) to Myrtle Beach (MYR) flights
- Spirit Airlines New York (LGA) to Myrtle Beach (MYR) flights
- American Airlines New York (JFK) to Myrtle Beach (MYR) flights
- Delta Minneapolis (MSP) to Myrtle Beach (MYR) flights
- Spirit Airlines Fort Lauderdale (FLL) to Myrtle Beach (MYR) flights
- American Airlines Chicago (ORD) to Myrtle Beach (MYR) flights
- JetBlue Airways Buffalo (BUF) to Boston (BOS) flights
- Delta Hartford (BDL) to Myrtle Beach (MYR) flights
- Spirit Airlines Detroit (DTW) to Myrtle Beach (MYR) flights
- American Airlines Buffalo (BUF) to Chicago (ORD) flights
- Delta Buffalo (BUF) to New York (LGA) flights
- United Buffalo (BUF) to Newark Liberty Intl. Airport (EWR) flights
- JetBlue Airways Buffalo (BUF) to Tampa (TPA) flights
- Flights from Buffalo (BUF) to Fort Lauderdale (FLL)
- Flights from Boston (BOS) to Miami (MIA)
- Flights from New York (LGA) to Miami (MIA)
- Flights from Buffalo (BUF) to Miami (MIA)
- Flights from New York (JFK) to London (LHR)
- Flights from Seattle (SEA) to Phoenix (PHX)
- Flights from Buffalo (BUF) to Phoenix (PHX)
- Flights from Buffalo (BUF) to Los Angeles (LAX)
- Flights from New York (NYC) to Los Angeles (LAX)
- Flights from Dallas (DFW) to Los Angeles (LAX)
- Flights from Seattle (SEA) to Los Angeles (LAX)
- Flights from Las Vegas (LAS) to Los Angeles (LAX)
- Flights from Buffalo (BUF) to New York (JFK)
- Flights from San Francisco (SFO) to New York (JFK)
- Flights from Buffalo (BUF) to Charlotte (CLT)
- Flights from Los Angeles (LAX) to New York (NYC)
- Flights from Miami (MIA) to New York (NYC)
- Flights from Atlanta (ATL) to New York (NYC)
- Flights from Dallas (DFW) to New York (NYC)
- Flights from Boston (BOS) to Orlando (MCO)
- Flights from Philadelphia (PHL) to Orlando (MCO)
- Flights from New York (JFK) to Orlando (MCO)
- Flights from Minneapolis (MSP) to Myrtle Beach (MYR)
- Flights from Chicago (ORD) to Myrtle Beach (MYR)
- Flights from Hartford (BDL) to Myrtle Beach (MYR)
- Flights from New York (LGA) to Myrtle Beach (MYR)
- Flights from Fort Lauderdale (FLL) to Myrtle Beach (MYR)
- Flights from Newark Liberty Intl. Airport (EWR) to Myrtle Beach (MYR)
- Flights from Buffalo (BUF) to Boston (BOS)
- Flights from Dallas (DFW) to Myrtle Beach (MYR)
- Flights from Detroit (DTW) to Myrtle Beach (MYR)
- Flights from Boston (BOS) to Myrtle Beach (MYR)
- Flights from Los Angeles (LAX) to Myrtle Beach (MYR)
- Flights from New York (JFK) to Myrtle Beach (MYR)
- Flights from Syracuse (SYR) to Myrtle Beach (MYR)
- Flights from Buffalo (BUF) to Chicago (ORD)
- Flights from Buffalo (BUF) to Punta Cana (PUJ)
- Flights from Portland (PDX) to Las Vegas (LAS)
- Flights from Dallas (DFW) to Las Vegas (LAS)
- Flights from Minneapolis (MSP) to Las Vegas (LAS)
- Flights from Atlanta (ATL) to Las Vegas (LAS)
- Flights from Chicago (ORD) to Las Vegas (LAS)
- Flights from Houston (IAH) to Las Vegas (LAS)
- Flights from New York (NYC) to Las Vegas (LAS)
- Flights from Los Angeles (LAX) to Las Vegas (LAS)
- Flights from Detroit (DTW) to Las Vegas (LAS)
- Flights from San Francisco (SFO) to Las Vegas (LAS)
- Flights from Seattle (SEA) to Las Vegas (LAS)
- Flights from Buffalo (BUF) to New York (LGA)
- Flights from Los Angeles (LAX) to Dallas (DFW)
- Flights from Buffalo (BUF) to Newark Liberty Intl. Airport (EWR)
- Flights from Los Angeles (LAX) to Seattle (SEA)
- Flights from New York (JFK) to Rome (FCO)
- Flights from Buffalo (BUF) to Tampa (TPA)
- Alaska Airlines
- Air Canada
- Delta
- KLM
- Etihad Airways
- Qatar Airways
- Copa
- Aeromexico
- JetBlue Airways
- Air France
- American Airlines
- Turkish Airlines
- British Airways
- United
- Frontier Airlines
- Lufthansa