$155 Cheap Flights from Buffalo (BUF) to Myrtle Beach (MYR)

Buffalo (BUF) to North Myrtle Beach (MYR) at a glance

Travel from Buffalo (BUF) to North Myrtle Beach (MYR) with a selection of airlines catering to this popular domestic short-haul route. Whether you're looking for full-service options or budget-friendly carriers, you can compare buffalo to Myrtle Beach flights to discover the best itinerary that aligns with your budget and schedule. Explore the renowned attractions and neighborhoods of North Myrtle Beach as you plan your getaway. Check out the key details for weekly flights from Buffalo Niagara International Airport to Myrtle Beach International Airport.

• Fastest (typical) flight duration: around 3 hours in-flight, plus roughly 1h 15m layover with one stop
• Route distance: roughly 600 miles (970 km)
• Flights per week: around 13 departures on average
• Typical fares (one-way): economy tickets often range from $105–$320, depending on seasonality and how far ahead you book

Flights from Buffalo Niagara International Airport (BUF) to Myrtle Beach International Airport (MYR)

According to recent traveler bookings, the top airlines flying from Buffalo to North Myrtle Beach are favored for their one-stop services, with common layovers at Charlotte-Douglas International Airport (CLT, approximately 55 minutes), Baltimore Washington International Thurgood Marshall Airport (BWI, around 1 hour and 15 minutes), and Ronald Reagan Washington National Airport (DCA, about 1 hour and 15 minutes). These options provide travelers with the flexibility to balance cost, total travel time, and cabin class while crafting their ideal itinerary.

• American Airlines: As a comprehensive carrier, American Airlines provides one-stop service with one-way ticket prices generally falling between $105 and $320. This airline represents about 50% of departures for this route, featuring an in-flight duration of 3 hours and an overall travel time of approximately 4 hours and 15 minutes, including the layover.
• Southwest Airlines: Known for its budget-friendly approach, Southwest Airlines also offers one-stop service, with one-way fares usually ranging from $105 to $340. It constitutes around 25% of the departures on this route, providing a flight time of 3 hours and a total journey time of roughly 4 hours and 15 minutes, including layover.
• Delta: Another major player in the full-service category, Delta offers one-stop service with one-way fares typically between $110 and $350. This airline accounts for about 21% of the departures on this route, with an in-flight time of 3 hours and a total travel duration of around 4 hours and 15 minutes, including the layover.
• United: United Airlines is a full-service provider offering one-stop service, with one-way fares usually ranging from $130 to $355. This carrier makes up about 3% of departures for this route, featuring a flight time of 3 hours and a total journey time of approximately 4 hours and 15 minutes, including the layover.

Travelers flying from Buffalo to North Myrtle Beach have the option to upgrade their flight. American Airlines offers first class, while Delta features both first class and premium economy service for added comfort during your journey.

Best time to fly from Buffalo (BUF) to North Myrtle Beach (MYR)

The most popular months for travelers flying from Buffalo to North Myrtle Beach are April, July, and August, when peak temperatures in North Myrtle Beach reach up to 81°F in July. If you prefer quieter travel, consider November, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 58.3°F. For better deals, September usually offers the lowest average one-way fare around $150. Flight availability peaks in August, with approximately 19 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 7 flights per week.

• Cheapest time to fly: September usually offers good deals with average one-way fare around $150, roughly 24% cheaper than the yearly average.
• Another budget-friendly time to fly: August typically offers an average one-way fare of around $168.
• Most flight options: August has the highest number of flights from Buffalo to North Myrtle Beach, with approximately 19 flights per week, giving you more flexibility in scheduling your trip.

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Buffalo (BUF) to North Myrtle Beach (MYR)

• Rochester to North Myrtle Beach (ROC-MYR): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy ticket prices for this journey generally fall between $55 and $340, influenced by the time of year and how far in advance you book. Travelers can choose from both non-stop and one-stop flights, with common layover points being Charlotte-Douglas International Airport (CLT) and Baltimore Washington International Thurgood Marshall Airport (BWI). Major airlines operating this route include American Airlines and Breeze (a budget airline). Additionally, service in business and first class is also available for this route.

How to find the best prices for flights from Buffalo (BUF) to North Myrtle Beach (MYR)

Getting some of the best deals on flights from Buffalo to North Myrtle Beach is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which aligns with when most travelers secure their flights. Afternoon departures (12pm-6pm) often offer lower prices, while morning flights (5am-12pm) are the most popular. Additionally, flying on Saturday provides both cheaper rates and is a favored travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find North Myrtle Beach hotel and flight deals.
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Myrtle Beach International Airport from Buffalo Niagara International Airport

North Myrtle Beach welcomes travelers from Buffalo with a range of transport options based on price, convenience, and proximity. Here's how to reach North Myrtle Beach efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in North Myrtle Beach, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
• Car rental: Renting a car from Myrtle Beach International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Myrtle Beach International Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Buffalo to Myrtle Beach Flights

The cheapest times to fly from Buffalo to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Myrtle Beach are during the month of September. You can find some of the cheapest flights from Buffalo to Myrtle Beach with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Buffalo to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Buffalo to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Buffalo to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Myrtle Beach in 2026. You can also book with separate airlines for your outbound and return journeys, from $155 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.