--- title: "Charleston to Florence cheap flights from $347 (CHS to FLO) - Expedia" description: "Book cheap Flights from Charleston (CHS) to Florence (FLO) start at $347 for one-way and $683 for round trip. Earn your airline miles on top of our rewards!" canonical: "https://www.expedia.com/lp/flights/chs/flo/charleston-to-florence" language: en-US market: US currency: USD prices_as_of: 2026-11-12T20:56:34Z --- # $347 Cheap Flights from Charleston (CHS) to Florence (FLO) ![A shopping mall with a Magnolia Mall sign and a Burlington store across the street.](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) [View $347 flight on Wed, Nov 25, 2026](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/25/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:346.81&airProductToken=AQppCjMIwYIBEgQzMTE0GOKRASDimgEovYueAzD%5Fi54DOEJAAFgBagVCQVNJQ3IITzBBV1pTQloKMgjBggESBDU5ODQY4poBIOVyKJ2PngMw3Y-eAzhCQAFYAWoFQkFTSUNyCE8wQVdaU0JaEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL) ## Popular airlines from Charleston Intl. Airport (CHS) to Florence, SC (FLO-Florence Regional) [American Airlines](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/26/2026TANYT&leg2=from:FLO,to:CHS,departure:12/3/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) ### Be in the know Get alerts if flight prices drop or rise\* ### Book smarter Save up to 30% on select hotels after you book a flight\* ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Charleston to Florence (CHS-FLO) Prices were available within the past 7 days and start at $347 for one-way flights and $683 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Charleston to Florence, returning Fri, Nov 27, priced at $683 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:CHS,departure:11/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:682.41&airProductToken=AQppCjMIwYIBEgQxNzMxGOKRASDimgEoqOqdAzD06p0DOEJAAFgBagVCQVNJQ3IITzBBV1pTQloKMgjBggESBDU5ODQY4poBIOVyKL3tnQMw%5Fe2dAzhCQAFYAWoFQkFTSUNyCE8wQVdaU0JaCmkKMgjBggESBDU4MzgY5XIg4poBKIGingMwwqKeAzhCQABYAWoFQkFTSUNyCE8wQVdaU0JaCjMIwYIBEgQ1NTYwGOKaASDikQEo9aWeAzDApp4DOEJAAVgBagVCQVNJQ3IITzBBV1pTQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) Sun, Nov 22 - Fri, Nov 27 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Wed, Nov 25 from Charleston to Florence, returning Sat, Nov 28, priced at $717 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/25/2026TANYT&leg2=from:FLO,to:CHS,departure:11/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:717.00&airProductToken=AQqbAQoyCMGCARIENDQ5MhjikQEgywEoxo6eAzDCj54DOEJAAFgBagVCQVNJQ3IIUVVBSlpTQlgKMQjBggESAzgwORjLASDimgEomJKeAzCgk54DOEJAAVgBagVCQVNJQ3IIUTBGV1VOQloKMgjBggESBDU4OTMY4poBIOVyKOaTngMwppSeAzhCQAFYAWoFQkFTSUNyCFEwRldVTkJaCpoBCjIIwYIBEgQ1ODM4GOVyIOKaASihrZ4DMOKtngM4QkAAWAFqBUJBU0lDcghRMEZXVU5CWAoxCMGCARIEMjgwMBjimgEgQyiYr54DMPWvngM4QkABWAFqBUJBU0lDcghRMEZXVU5CWAoxCMGCARIENTIwNBhDIOKRASjcsp4DMNOzngM4QkABWAFqBUJBU0lDcghRVUZIWk5CWhIMCAEQARgBKgJBQTIAGAEiBAgBEAEoAigDKAQwCw) Wed, Nov 25 - Sat, Nov 28 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Wed, Nov 25 from Charleston to Florence, returning Sat, Nov 28, priced at $771 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/25/2026TANYT&leg2=from:FLO,to:CHS,departure:11/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:770.01&airProductToken=AQqbAQoyCMGCARIENDQ5MhjikQEgywEoxo6eAzDCj54DOEJAAFgBagVCQVNJQ3IIUVVBSlpTQlgKMQjBggESAzgwORjLASDimgEomJKeAzCgk54DOEJAAVgBagVCQVNJQ3IIUTBGV1VOQloKMgjBggESBDU4OTMY4poBIOVyKOaTngMwppSeAzhCQAFYAWoFQkFTSUNyCFEwRldVTkJaCpwBCjIIwYIBEgQ1ODM4GOVyIOKaASihrZ4DMOKtngM4QkAAWAFqBUJBU0lDcghOMEZXVU5CWgoyCMGCARIEMTg4NRjimgEgywEoqK-eAzCXsJ4DOEJAAVgBagVCQVNJQ3IITjBGV1VOQloKMgjBggESBDQzNjgYywEg4pEBKJ-yngMwrrOeAzhCQAFYAWoFQkFTSUNyCE5VRkhaTkJaEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL) Wed, Nov 25 - Sat, Nov 28 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Charleston to Florence, returning Fri, Nov 27, priced at $794 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:CHS,departure:11/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:793.61&airProductToken=AQpnCjIIwYIBEgQyNzI1GOKRASDimgEop--dAzDz750DOE9AAFgBagRNQUlOcghPMEFXWlNNMQoxCMGCARIENTg5MxjimgEg5XIohvKdAzDG8p0DOE9AAVgBagRNQUlOcghPMEFXWlNNMRIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) Sun, Nov 22 - Fri, Nov 27 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Charleston to Florence, returning Fri, Nov 27, priced at $813 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:CHS,departure:11/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:812.41&airProductToken=AQppCjMIwYIBEgQ1NjQxGOKRASDimgEozOudAzCd7J0DOEJAAFgBagVCQVNJQ3IITzBBV1pTQloKMgjBggESBDU5ODQY4poBIOVyKL3tnQMw%5Fe2dAzhCQAFYAWoFQkFTSUNyCE4wRldaTkJaCmkKMgjBggESBDU4MzgY5XIg4poBKIGingMwwqKeAzhCQABYAWoFQkFTSUNyCE8wQVdaU0JaCjMIwYIBEgQ1NTYwGOKaASDikQEo9aWeAzDApp4DOEJAAVgBagVCQVNJQ3IITzBBV1pTQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) Sun, Nov 22 - Fri, Nov 27 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Tue, Nov 17 from Charleston to Florence, returning Tue, Nov 24, priced at $831 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/17/2026TANYT&leg2=from:FLO,to:CHS,departure:11/24/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:830.70&airProductToken=AQqbAQoyCMGCARIEMjg3NhjikQEgrhwovbKdAzDks50DOEJAAFgBagVCQVNJQ3IIUzBBWlpOQloKMQjBggESAzg2NBiuHCDimgEosLedAzC0uJ0DOEJAAVgBagVCQVNJQ3IITzBBV1VOQloKMgjBggESBDU4OTMY4poBIOVyKK-5nQMw77mdAzhCQAFYAWoFQkFTSUNyCE8wQVdVTkJaCmkKMgjBggESBDU5ODQY5XIg4poBKNeEngMwmoWeAzhCQABYAWoFQkFTSUNyCE8wQVdaU0JaCjMIwYIBEgQxMjY5GOKaASDikQEoxoieAzCHiZ4DOEJAAVgBagVCQVNJQ3IITzBBV1pTQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) Tue, Nov 17 - Tue, Nov 24 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Sun, Nov 22 from Charleston to Florence, returning Fri, Nov 27, priced at $843 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/22/2026TANYT&leg2=from:FLO,to:CHS,departure:11/27/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:842.60&airProductToken=AQprCjQIwYIBEgQzMTE0GOKRASDimgEo3emdAzCf6p0DOE9AAFgBagZNQUlORkxyCE8wQVdaUlYxCjMIwYIBEgQ1OTg0GOKaASDlcii97Z0DMP3tnQM4T0ABWAFqBk1BSU5GTHIITzBBV1pSVjESCggBEAEYASoCQUEYASIECAEQASgCKAQoBjAL) Sun, Nov 22 - Fri, Nov 27 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Tue, Nov 17 from Charleston to Florence, returning Tue, Nov 24, priced at $845 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/17/2026TANYT&leg2=from:FLO,to:CHS,departure:11/24/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:845.00&airProductToken=AQqbAQoyCMGCARIEMjg3NhjikQEgrhwovbKdAzDks50DOEJAAFgBagVCQVNJQ3IIUzBBWlpOQloKMQjBggESAzg2NBiuHCDimgEosLedAzC0uJ0DOEJAAVgBagVCQVNJQ3IITzBBV1VOQloKMgjBggESBDU4OTMY4poBIOVyKK-5nQMw77mdAzhCQAFYAWoFQkFTSUNyCE8wQVdVTkJaCpkBCjIIwYIBEgQ1OTg0GOVyIOKaASjXhJ4DMJqFngM4QkAAWAFqBUJBU0lDcghRMEZXVU5CWAowCMGCARIDNjEyGOKaASBDKNqFngMwvYaeAzhCQAFYAWoFQkFTSUNyCFEwRldVTkJYCjEIwYIBEgQxNjQ2GEMg4pEBKM6HngMws4ieAzhCQAFYAWoFQkFTSUNyCFFVRkhaTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Tue, Nov 17 - Tue, Nov 24 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Wed, Nov 25 from Charleston to Florence, returning Sat, Nov 28, priced at $859 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/25/2026TANYT&leg2=from:FLO,to:CHS,departure:11/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:858.91&airProductToken=AQppCjMIwYIBEgQxNzMxGOKRASDimgEoiIyeAzDUjJ4DOEJAAFgBagVCQVNJQ3IITzBBV1pTQloKMgjBggESBDU5ODQY4poBIOVyKJ2PngMw3Y-eAzhCQAFYAWoFQkFTSUNyCE8wQVdaU0JaEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL) Wed, Nov 25 - Sat, Nov 28 · CHS · FLO · Roundtrip [Select American Airlines flight, departing Wed, Nov 25 from Charleston to Florence, returning Sat, Nov 28, priced at $875 Found 14 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CHS,to:FLO,departure:11/25/2026TANYT&leg2=from:FLO,to:CHS,departure:11/28/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:874.41&airProductToken=AQppCjMIwYIBEgQzMTE0GOKRASDimgEovYueAzD%5Fi54DOEJAAFgBagVCQVNJQ3IITzBBV1pTQloKMgjBggESBDU5ODQY4poBIOVyKJ2PngMw3Y-eAzhCQAFYAWoFQkFTSUNyCE8wQVdaU0JaCmkKMgjBggESBDU4MzgY5XIg4poBKKGtngMw4q2eAzhCQABYAWoFQkFTSUNyCE4wRldVTkJaCjMIwYIBEgQ1NTYwGOKaASDikQEomrGeAzDlsZ4DOEJAAVgBagVCQVNJQ3IITjBGV1VOQloSDAgBEAEYASoCQUEyABgBIgQIARABKAIoAygEMAs) Wed, Nov 25 - Sat, Nov 28 · CHS · FLO · Roundtrip ## Book with confidence ### Charleston to Florence Flights #### The cheapest times to fly from Charleston to Florence On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to Florence are during the month of November. You can find some of the cheapest flights from Charleston to Florence with Expedia's search tool and vast selection of airlines. #### The best time to book a flight from Charleston to Florence Sunday is one of the best days to book for cheap flights from Charleston to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. #### How to find cheap round-trip tickets from Charleston to Florence Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to Florence in 2026\. You can also book with separate airlines for your outbound and return journeys, from $347 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Charleston to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. *\*Terms apply.* *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Frequently Asked Questions ### How much does a flight from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) cost? You can find cheap one-way flights from $347 and cheap return flights $683 CHS to FLO with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when CHS to FLO ticket fares go up or down. ### What is the cheapest month to fly from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? The cheapest month to fly from CHS to FLO is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route. ### Which airlines fly direct from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? Enter CHS to FLO and your travel dates, then apply the 'Nonstop' filter to see only direct flights. ### What is the cheapest airline that flies from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? American Airlines is the carrier that flies from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional). Use Expedia's flight search tool to compare airlines on this route and find our cheapest option for your trip. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget. *\*Prices based on flights available on Expedia in the last year.* ### How do I find cheap flights from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? To find a cheap flight from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down. ### What is the best time to fly from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience. ### What is the earliest flight from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from CHS to FLO. To compare more early flights, use the "Early Morning" and "Morning" filters in your search. ### How long does it take to fly from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? Flying from CHS to FLO with a connection usually takes about 5 hours, traveling roughly 92 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic. ### Can you fly business or first class from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? Select the "Business class" and "First class" filters when looking for CHS to FLO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip. ### How do I earn miles on a Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) flight with Expedia? It's easy to earn miles on a Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia. \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands. ### What airports do you fly into for Florence from Charleston Intl. (CHS)? If you're planning to travel to Florence from Charleston Intl. (CHS), you can fly typically into Peretola (FLR) Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL), Washington Dulles Intl. (IAD), John F. Kennedy Intl. (JFK) before reaching Florence. Compare routes and airports on Expedia to find the best flight options for your travel plans. ### Is it cheaper to buy a plane ticket from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) at the last minute? Typically, booking a last minute flight from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare. ### Is it cheaper to book a Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package? Securing a Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars. ### Can I cancel or change the date of my flight from Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional)? If you booked your Charleston, SC (CHS-Charleston Intl.) to Florence, SC (FLO-Florence Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information. ## Travel information | Origin airport | Charleston Intl. Airport | | ------------------- | ------------------------ | | Destination airport | Florence, SC | | Distance | 92 miles away | | Airlines serving | American Airlines | | Popular airline | American Airlines | | Roundtrip price | $683 | ## Explore a world of travel with Expedia - [Flights](?equalTargetTab=tab-0) - [Flights from Philadelphia (PHL) to Florence (FLO)](https://www.expedia.com/lp/flights/phl/flo/philadelphia-to-florence) - [Flights from Washington (DCA) to Florence (FLO)](https://www.expedia.com/lp/flights/dca/flo/washington-to-florence) - [Flights from Indianapolis (IND) to Florence (FLO)](https://www.expedia.com/lp/flights/ind/flo/indianapolis-to-florence) - [Flights from Minneapolis (MSP) to Florence (FLO)](https://www.expedia.com/lp/flights/msp/flo/minneapolis-to-florence) - [Flights from Detroit (DTW) to Florence (FLO)](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Portland (PDX) to Florence (FLO)](https://www.expedia.com/lp/flights/pdx/flo/portland-to-florence) - [Flights from New York (NYC) to Florence (FLO)](https://www.expedia.com/lp/flights/nyc/flo/new-york-to-florence) - [Flights from San Antonio (SAT) to Florence (FLO)](https://www.expedia.com/lp/flights/sat/flo/san-antonio-to-florence) - [Flights from Louisville (SDF) to Florence (FLO)](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Raleigh (RDU) to Florence (FLO)](https://www.expedia.com/lp/flights/rdu/flo/raleigh-to-florence) - [Flights from Newark Liberty Intl. Airport (EWR) to Florence (FLO)](https://www.expedia.com/lp/flights/ewr/flo/newark-liberty-intl-airport-to-florence) - [Flights from Fort Lauderdale (FLL) to Florence (FLO)](https://www.expedia.com/lp/flights/fll/flo/fort-lauderdale-to-florence) - [Flights from New York (JFK) to Florence (FLO)](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - [Flights from Mobile (MOB) to Florence (FLO)](https://www.expedia.com/lp/flights/mob/flo/mobile-to-florence) - [Flights from Boston (BOS) to Myrtle Beach (MYR)](https://www.expedia.com/lp/flights/bos/myr/boston-to-myrtle-beach) - [Flights from Missoula (MSO) to Florence (FLO)](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Oklahoma City (OKC) to Florence (FLO)](https://www.expedia.com/lp/flights/okc/flo/oklahoma-city-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO)](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from London (LHR) to Florence (FLO)](https://www.expedia.com/lp/flights/lhr/flo/london-to-florence) - [Flights from Pensacola (PNS) to Florence (FLO)](https://www.expedia.com/lp/flights/pns/flo/pensacola-to-florence) - [Flights from Syracuse (SYR) to Florence (FLO)](https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence) - [Flights from Houston (IAH) to Florence (FLO)](https://www.expedia.com/lp/flights/iah/flo/houston-to-florence) - [Flights from Nashville (BNA) to Florence (FLO)](https://www.expedia.com/lp/flights/bna/flo/nashville-to-florence) - [Flights from New York (LGA) to Florence (FLO)](https://www.expedia.com/lp/flights/lga/flo/new-york-to-florence) - [Flights from Charlotte (CLT) to Florence (FLO)](https://www.expedia.com/lp/flights/clt/flo/charlotte-to-florence) - [Flights from Rochester (ROC) to Florence (FLO)](https://www.expedia.com/lp/flights/roc/flo/rochester-to-florence) - [Flights from Huntsville (HSV) to Florence (FLO)](https://www.expedia.com/lp/flights/hsv/flo/huntsville-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO)](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO)](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from Los Angeles (LAX) to Florence (FLO)](https://www.expedia.com/lp/flights/lax/flo/los-angeles-to-florence) - [Flights from Newburgh (SWF) to Florence (FLO)](https://www.expedia.com/lp/flights/swf/flo/newburgh-to-florence) - [Flights from Tucson (TUS) to Florence (FLO)](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Austin (AUS) to Florence (FLO)](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from Asheville (AVL) to Florence (FLO)](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from El Paso (ELP) to Florence (FLO)](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Savannah (SAV) to Florence (FLO)](https://www.expedia.com/lp/flights/sav/flo/savannah-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO)](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from Sacramento (SMF) to Florence (FLO)](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO)](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from Appleton (ATW) to Florence (FLO)](https://www.expedia.com/lp/flights/atw/flo/appleton-to-florence) - [Flights from Hartford (BDL) to Florence (FLO)](https://www.expedia.com/lp/flights/bdl/flo/hartford-to-florence) - [Flights from Dayton (DAY) to Florence (FLO)](https://www.expedia.com/lp/flights/day/flo/dayton-to-florence) - [Flights from Boston (BOS) to Florence (FLO)](https://www.expedia.com/lp/flights/bos/flo/boston-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO)](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from Latrobe (LBE) to Florence (FLO)](https://www.expedia.com/lp/flights/lbe/flo/latrobe-to-florence) - [Flights from Little Rock (LIT) to Florence (FLO)](https://www.expedia.com/lp/flights/lit/flo/little-rock-to-florence) - [Flights from Tulsa (TUL) to Florence (FLO)](https://www.expedia.com/lp/flights/tul/flo/tulsa-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO)](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Atlanta (ATL) to Florence (FLO)](https://www.expedia.com/lp/flights/atl/flo/atlanta-to-florence) - [Flights from St. Louis (STL) to Florence (FLO)](https://www.expedia.com/lp/flights/stl/flo/st-louis-to-florence) - [Flights from Tampa (TPA) to Florence (FLO)](https://www.expedia.com/lp/flights/tpa/flo/tampa-to-florence) - [Flights from Norfolk (ORF) to Florence (FLO)](https://www.expedia.com/lp/flights/orf/flo/norfolk-to-florence) - [Flights from Albany (ALB) to Florence (FLO)](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Phoenix (PHX) to Florence (FLO)](https://www.expedia.com/lp/flights/phx/flo/phoenix-to-florence) - [Flights from Sarasota (SRQ) to Florence (FLO)](https://www.expedia.com/lp/flights/srq/flo/sarasota-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO)](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO)](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Washington (IAD) to Florence (FLO)](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Evansville (EVV) to Florence (FLO)](https://www.expedia.com/lp/flights/evv/flo/evansville-to-florence) - [Flights from Lexington (LEX) to Florence (FLO)](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Columbus (CMH) to Florence (FLO)](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from New Haven (HVN) to Florence (FLO)](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO)](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from Wilmington (ILM) to Florence (FLO)](https://www.expedia.com/lp/flights/ilm/flo/wilmington-to-florence) - [Flights from Chicago (ORD) to Florence (FLO)](https://www.expedia.com/lp/flights/ord/flo/chicago-to-florence) - [Flights from Denver (DEN) to Florence (FLO)](https://www.expedia.com/lp/flights/den/flo/denver-to-florence) - [Flights from Greenville (GSP) to Florence (FLO)](https://www.expedia.com/lp/flights/gsp/flo/greenville-to-florence) - [Flights from Las Vegas (LAS) to Florence (FLO)](https://www.expedia.com/lp/flights/las/flo/las-vegas-to-florence) - [Flights from Dothan (DHN) to Florence (FLO)](https://www.expedia.com/lp/flights/dhn/flo/dothan-to-florence) - [Flights from Providence (PVD) to Florence (FLO)](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from San Diego (SAN) to Florence (FLO)](https://www.expedia.com/lp/flights/san/flo/san-diego-to-florence) - [Flights from San Luis Obispo (SBP) to Florence (FLO)](https://www.expedia.com/lp/flights/sbp/flo/san-luis-obispo-to-florence) - [Flights from Eugene (EUG) to Florence (FLO)](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Knoxville (TYS) to Florence (FLO)](https://www.expedia.com/lp/flights/tys/flo/knoxville-to-florence) - [Flights from Richmond (RIC) to Florence (FLO)](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Myrtle Beach (MYR) to Florence (FLO)](https://www.expedia.com/lp/flights/myr/flo/myrtle-beach-to-florence) - [Flights from Fort Myers (RSW) to Florence (FLO)](https://www.expedia.com/lp/flights/rsw/flo/fort-myers-to-florence) - [Flights from Fayetteville (XNA) to Florence (FLO)](https://www.expedia.com/lp/flights/xna/flo/fayetteville-to-florence) - [Flights from Rzeszow (RZE) to Florence (FLO)](https://www.expedia.com/lp/flights/rze/flo/rzeszow-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO)](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO)](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from South Bend (SBN) to Florence (FLO)](https://www.expedia.com/lp/flights/sbn/flo/south-bend-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO)](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from Dallas (DFW) to Florence (FLO)](https://www.expedia.com/lp/flights/dfw/flo/dallas-to-florence) - [Flights from Memphis (MEM) to Florence (FLO)](https://www.expedia.com/lp/flights/mem/flo/memphis-to-florence) - [Flights from Augusta (AGS) to Florence (FLO)](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO)](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO)](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Milwaukee (MKE) to Florence (FLO)](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Anchorage (ANC) to Florence (FLO)](https://www.expedia.com/lp/flights/anc/flo/anchorage-to-florence) - [Flights from Orlando (MCO) to Florence (FLO)](https://www.expedia.com/lp/flights/mco/flo/orlando-to-florence) - [Flights from Columbia (CAE) to Florence (FLO)](https://www.expedia.com/lp/flights/cae/flo/columbia-to-florence) - [Flights from Fort Walton Beach (VPS) to Florence (FLO)](https://www.expedia.com/lp/flights/vps/flo/fort-walton-beach-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO)](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO)](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Jacksonville (JAX) to Florence (FLO)](https://www.expedia.com/lp/flights/jax/flo/jacksonville-to-florence) - [Flights from Miami (MIA) to Florence (FLO)](https://www.expedia.com/lp/flights/mia/flo/miami-to-florence) - [Flights from Allentown (ABE) to Florence (FLO)](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Seattle (SEA) to Florence (FLO)](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Baltimore (BWI) to Florence (FLO)](https://www.expedia.com/lp/flights/bwi/flo/baltimore-to-florence) \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/lp/flights/chs/flo/charleston-to-florence de-DE: https://www.expedia.de/lp/fluge/chs/flo/charleston-nach-florence ar: https://www.expedia.sa/lp/flights/chs/flo/charleston-to-florence es: https://www.expedia.com/es/lp/vuelos/chs/flo/charleston-a-florence en-US: https://www.expedia.com/lp/flights/chs/flo/charleston-to-florence ```