Title: $354 Cheap flights from Rochester to Florence (ROC to FLO) - Expedia.com ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $354 Cheap Flights from Rochester (ROC) to Florence (FLO) [View $354 flight on Sat, Aug 15, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:ROC,to:FLO,departure:8/15/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:353.10&airProductToken=AQqaAQoxCMGCARIENDEwNBjREyCuHCjMkpUDMMiTlQM4QkAAWAFqBUJBU0lDcghRV0FJWk5CWgoxCMGCARIDNjI3GK4cIOKaASjElZUDMMaWlQM4QkABWAFqBUJBU0lDcghPV0FXWE5CWAoyCMGCARIENjEwMRjimgEg5XIo55eVAzCymJUDOEJAAVgBagVCQVNJQ3IIT1dBV1hOQlgSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travelers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Greater Rochester Intl. Airport (ROC) to Florence, SC (FLO-Florence Regional) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.com/Flights-Search?leg1=from:ROC,to:FLO,departure:2/19/2026TANYT&leg2=from:FLO,to:ROC,departure:2/26/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheap Flights from Rochester to Florence (ROC-FLO) Prices were available within the past 7 days and start at $354 for one-way flights and $433 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Aug 15 - Sat, Aug 22 ROC Rochester FLO Florence $433 Roundtrip found 3 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:8/15/2026TANYT&leg2=from:FLO,to:ROC,departure:8/22/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:432.40&airProductToken=AQpoCjIIwYIBEgQyMzIwGNETIOKaASiglZUDMJWWlQM4QkAAWAFqBUJBU0lDcghPV0ZXVU5CWgoyCMGCARIENjEwMRjimgEg5XIo55eVAzCymJUDOEJAAVgBagVCQVNJQ3IIT1dGV1VOQloKaAoyCMGCARIENTkyMBjlciDimgEoqt6VAzD13pUDOEJAAFgBagVCQVNJQ3IIT1dGV1VOQloKMgjBggESBDU2MzAY4poBINETKJjglQMwk-GVAzhCQAFYAWoFQkFTSUNyCE9XRldVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Aug 15 - Sat, Aug 22 ROC Rochester FLO Florence $461 Roundtrip found 3 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:8/15/2026TANYT&leg2=from:FLO,to:ROC,departure:8/22/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:460.41&airProductToken=AQpoCjIIwYIBEgQyMzIwGNETIOKaASiglZUDMJWWlQM4QkAAWAFqBUJBU0lDcghPV0ZXVU5CWgoyCMGCARIENjEwMRjimgEg5XIo55eVAzCymJUDOEJAAVgBagVCQVNJQ3IIT1dGV1VOQloKaAoyCMGCARIENTk4NhjlciDimgEok-GVAzDZ4ZUDOEJAAFgBagVCQVNJQ3IIUTBGV1VOQloKMgjBggESBDIzMjAY4poBINETKPDilQMw2OOVAzhCQAFYAWoFQkFTSUNyCFEwRldVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, Feb 18 - Tue, Mar 3 ROC Rochester FLO Florence $466 Roundtrip found 6 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:2/18/2026TANYT&leg2=from:FLO,to:ROC,departure:3/3/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:465.71&airProductToken=AQqdAQoyCMGCARIENDYwMBjREyDBkwEosL6FAzCKv4UDOEJAAFgBagVCQVNJQ3IIUTBGV1VOQloKMwjBggESBDE2ODgYwZMBIOKaASjkv4UDMP_AhQM4QkABWAFqBUJBU0lDcghRMEZXVU5CWgoyCMGCARIENTk4MxjimgEg5XIo28KFAzCdw4UDOEJAAVgBagVCQVNJQ3IIUTBGV1VOQloKaAoyCMGCARIENTgzOBjlciDimgEoo9CGAzDp0IYDOEJAAFgBagVCQVNJQ3IIT1dGV1VOQloKMgjBggESBDE0MzgY4poBINETKNPShgMwytOGAzhCQAFYAWoFQkFTSUNyCE9XRldVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, Feb 18 - Tue, Mar 3 ROC Rochester FLO Florence $472 Roundtrip found 6 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:2/18/2026TANYT&leg2=from:FLO,to:ROC,departure:3/3/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:471.01&airProductToken=AQqdAQoyCMGCARIENjA2NxjREyDBkwEo5sCFAzC-wYUDOEJAAFgBagVCQVNJQ3IIUTBGV1VOQloKMwjBggESBDE0OTUYwZMBIOKaASimw4UDMMrEhQM4QkABWAFqBUJBU0lDcghRMEZXVU5CWgoyCMGCARIENTg5MxjimgEg5XIoucWFAzD4xYUDOEJAAVgBagVCQVNJQ3IIUTBGV1VOQloKmwEKMgjBggESBDU4MzgY5XIg4poBKKPQhgMw6dCGAzhCQABYAWoFQkFTSUNyCE9XRldVTkJaCjIIwYIBEgQxODA5GOKaASDvWSig0YYDMIrShgM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWgoxCMGCARIENjEzMBjvWSDREyjd0oYDMLjThgM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Mar 9 - Tue, Mar 17 ROC Rochester FLO Florence $472 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:3/9/2026TANYT&leg2=from:FLO,to:ROC,departure:3/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:471.70&airProductToken=AQpoCjIIwYIBEgQxNDM4GNETIOKaASjulocDMO2XhwM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTk4MxjimgEg5XIonJiHAzDemIcDOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKmwEKMgjBggESBDU4MzgY5XIg4poBKKfthwMw7e2HAzhCQABYAWoFQkFTSUNyCE9XRldVTkJaCjIIwYIBEgQxODA5GOKaASDvWSik7ocDMI7vhwM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWgoxCMGCARIENjEzMBjvWSDREyjg74cDMLvwhwM4QkABWAFqBUJBU0lDcghPV0ZXVU5CWhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Aug 11 - Wed, Aug 26 ROC Rochester FLO Florence $487 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:8/11/2026TANYT&leg2=from:FLO,to:ROC,departure:8/26/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:487.00&airProductToken=AQpmCh8IwYIBEgQzOTk3GNETIEMo2eWUAzCq5pQDOE9AAFgBCiAIwYIBEgQyMTgyGEMg4poBKK_olAMwmemUAzhPQAFYAQohCMGCARIENjEwMRjimgEg5XIo5-qUAzCy65QDOE9AAVgBCmYKIQjBggESBDU5MjAY5XIg4poBKKqLlgMw9YuWAzhPQABYAQogCMGCARIEMTU4MRjimgEgQyjSjJYDMKSNlgM4T0ABWAEKHwjBggESBDU0NTcYQyDREyivkJYDMICRlgM4T0ABWAESCggBEAEYASoCQUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Mar 16 - Tue, Mar 24 ROC Rochester FLO Florence $495 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:3/16/2026TANYT&leg2=from:FLO,to:ROC,departure:3/24/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:494.40&airProductToken=AQpnCjEIwYIBEgMzNzAY0RMg4poBKOLnhwMw4-iHAzhCQABYAWoFQkFTSUNyCE9XRldaTkJaCjIIwYIBEgQ1ODkzGOKaASDlciju6YcDMK3qhwM4QkABWAFqBUJBU0lDcghPV0ZXWk5CWgpoCjIIwYIBEgQ1ODM4GOVyIOKaASiHvIgDMM28iAM4QkAAWAFqBUJBU0lDcghRMEZXVU5CWgoyCMGCARIEMTQzOBjimgEg0RMot76IAzCuv4gDOEJAAVgBagVCQVNJQ3IIUTBGV1VOQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Aug 15 - Sat, Aug 22 ROC Rochester FLO Florence $496 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:8/15/2026TANYT&leg2=from:FLO,to:ROC,departure:8/22/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:495.41&airProductToken=AQpoCjIIwYIBEgQxMDU4GNETIOKaASiUkJUDMImRlQM4QkAAWAFqBUJBU0lDcghPV0ZXVU5CWgoyCMGCARIENTk4NhjimgEg5XIozJGVAzCakpUDOEJAAVgBagVCQVNJQ3IIT1dGV1VOQloKaAoyCMGCARIENTk4NhjlciDimgEok-GVAzDZ4ZUDOEJAAFgBagVCQVNJQ3IITjBGV1VOQloKMgjBggESBDIzMjAY4poBINETKPDilQMw2OOVAzhCQAFYAWoFQkFTSUNyCE4wRldVTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, Mar 20 - Sun, Mar 22 ROC Rochester FLO Florence $501 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:3/20/2026TANYT&leg2=from:FLO,to:ROC,departure:3/22/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:500.40&airProductToken=AQpoCjIIwYIBEgQxNDM4GNETIOKaASjOkogDMM2TiAM4QkAAWAFqBUJBU0lDcghPV0ZXWk5CWgoyCMGCARIENTk4MxjimgEg5XIo_JOIAzC-lIgDOEJAAVgBagVCQVNJQ3IIT1dGV1pOQloKaAoyCMGCARIENTk4MxjlciDimgEonKuIAzDiq4gDOEJAAFgBagVCQVNJQ3IIT1dGV1pOQloKMgjBggESBDMwMjYY4poBINETKK2siAMwmK2IAzhCQAFYAWoFQkFTSUNyCE9XRldaTkJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Aug 8 - Wed, Aug 26 ROC Rochester FLO Florence $502 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ROC,to:FLO,departure:8/8/2026TANYT&leg2=from:FLO,to:ROC,departure:8/26/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:502.00&airProductToken=AQpmCh8IwYIBEgQ1MzUxGNETIEMo-sCUAzDKwZQDOFFAAFgBCiAIwYIBEgQyMTgyGEMg4poBKM_GlAMwuceUAzhPQAFYAQohCMGCARIENjEwMRjimgEg5XIoh8mUAzDSyZQDOE9AAVgBCmYKIQjBggESBDU5MjAY5XIg4poBKKqLlgMw9YuWAzhPQABYAQogCMGCARIEMTU4MRjimgEgQyjSjJYDMKSNlgM4T0ABWAEKHwjBggESBDU0NTcYQyDREyivkJYDMICRlgM4T0ABWAESCggBEAEYASoCQUEYASIECAEQASgEMAE) __Flights from Rochester (ROC) to Florence (FLO)__ | Origin airport | Greater Rochester Intl. | | ------------------- | ----------------------- | | Destination airport | Florence Regional | | Airlines serving | American Airlines | | Roundtrip price | $432 | | Distance | 627 mi | ## Rochester to Florence Flights The cheapest times to fly from Rochester to Florence On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rochester to Florence are during the month of August. You can find some of the cheapest flights from Rochester to Florence with Expedia's search tool and vast selection of airlines. The best time to book a flight from Rochester to Florence Sunday is one of the best days to book for cheap flights from Rochester to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. How to find cheap round-trip tickets from Rochester to Florence Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rochester to Florence in 2026\. You can also book with separate airlines for your outbound and return journeys, from $354 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rochester to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Rochester to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. \*Terms apply. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. ## Frequently asked questions ### How much does a flight from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional) cost? ### What is the cheapest month to fly from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### Which airlines fly direct from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### What is the cheapest airline that flies from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### How do I find cheap flights from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### What is the best time to fly from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### What is the earliest flight from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### What are the most popular departure times for flights from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### How long does it take to fly from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### Can you fly business or first class from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? ### How do I earn miles on a Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional) flight with Expedia? ### What airports do you fly into for Florence from Greater Rochester Intl. (ROC)? ### Is it cheaper to buy a plane ticket from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional) at the last minute? ### Is it cheaper to book a Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional) flight and hotel package? ### Can I cancel or change the date of my flight from Rochester, NY (ROC-Greater Rochester Intl.) to Florence, SC (FLO-Florence Regional)? \*Flight schedules are subject to change. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Florence Hotels ](https://www.expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - 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