Title: Top Red Roof Inn in Florence, SC from $63 - Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 17 - Mar 18](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-17&endDate=2026-03-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 18 - Mar 19](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-18&endDate=2026-03-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence Red Roof Inn ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/76254b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Non Smoking (Roll-In Shower) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/2b946657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/31819118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/edb6be2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Dillon, SC [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) Dillon 6.4/10 (1,001 reviews) "Room was clean, staff very helpful and kind. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge $56 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/ae830b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/0c25e0a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/4165fb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/bbdb0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Sumter [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) Sumter 6.8/10 (289 reviews) "The lady that checked me in was super nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole $110 nightly $123 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/868ff462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/f14e88ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/6673044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Florence 6.8/10 (1,004 reviews) "It met our needs for an overnight stay. Clean, quiet and safe. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) philip $56 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Desk, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/79100656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/e212e1b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/fa0bcb0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/3073a472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Bishopville [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Bishopville.h24204.Hotel-Information) Bishopville 6.2/10 (139 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedrin $75 nightly $84 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Bishopville.h24204.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-31&endDate=2026-04-01®ionId=1221&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels) ## Top Florence Hotel Reviews ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 8/10 Good "I would stay again. The floor above walking was a bit obnoxious. But I still had a good night sleep. Staff was pleasant." [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "Very clean rooms and nice staff. We always stay here when I'm Florence. Walking distance to all of downtown." [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Fairfield Inn & Suites by Marriott Florence I-20](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640_y.jpg) ### Fairfield Inn & Suites by Marriott Florence I-20 8/10 Good "Good" [](https://expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "We had a great stay.The continental breakfast could have been a little more robust, but for the price for the room it was great and the rooms were clean and everything was wonderful." [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "The room was excellent" [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "The staff at the desk are so nice and understanding and the housekeepers be on top everything. They are so clean and the room are really nice. " [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Staybridge Suites Florence - Civic Center by IHG](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a_y.jpg) ### Staybridge Suites Florence - Civic Center by IHG 10/10 Excellent "Stayed for one night while traveling to Florida. Very comfortable one bedroom suite. " [](https://expedia.com/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Clean room, friendly staff and ample parking, breakfast is ok. " [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 6/10 Okay "Booked because it was the lowest price for not a Motel 6 or Red Roof. Small room, no problem. Big fridge. Free coffee in the AM. Property is run down but bed and bathroom were clean. " [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - [Flights from Florence Regional ](https://www.expedia.com/lp/airports/flo/flights-from-florence-regional-airport) - [Flights from New York (JFK) to Florence (FLO) ](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - 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