Title: Top Red Roof Inn in Florence, SC from $65 - Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Florence. Italy. Panorama of Florence on a sunny day.](https://images.trvl-media.com/place/1221/374d4531-94f4-49c0-ae64-4d3f066e98eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1221/374d4531-94f4-49c0-ae64-4d3f066e98eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates Tonight [Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 1 - Apr 2](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence Red Roof Inn ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/76254b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/009ea869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/edb6be2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Non Smoking (Roll-In Shower) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/2b946657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Dillon, SC [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) Dillon 6.4/10 (1,008 reviews) "It has great rooms just needs some loving in the room but otherwise a good hotel the staff was kind and helpful when needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kaitlin $58 nightly $65 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/ae830b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/4165fb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/0c25e0a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/33c86cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Sumter [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) Sumter 6.8/10 (292 reviews) "The lady that checked me in was super nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole $110 nightly $123 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/868ff462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/f14e88ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Florence 6.8/10 (1,002 reviews) "It met our needs for an overnight stay. Clean, quiet and safe. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) philip $61 nightly $68 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Desk, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/79100656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/3073a472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/e212e1b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/6fb30800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Bishopville [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Bishopville.h24204.Hotel-Information) Bishopville 6.2/10 (142 reviews) "Good for a day or 2 but not a long time " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clarenca $75 nightly $84 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Bishopville.h24204.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-14&endDate=2026-04-15®ionId=1221&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels) ## Top Florence Hotel Reviews ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 8/10 Good "The location is great! You can walk to the Cook Out and other restaurants. The room is dated with older carpeting etc but the bed was comfortable. The free breakfast was quite basic. They did have cold boiled eggs which I liked but it was breads, cereals and coffee. For the price we paid it was perfect for a one night stay. " [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent " Wonderful stay " [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Fairfield Inn & Suites by Marriott Florence I-20](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640_y.jpg) ### Fairfield Inn & Suites by Marriott Florence I-20 10/10 Excellent "Excellent" [](https://expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![SpringHill Suites by Marriott Florence](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c_y.jpg) ### SpringHill Suites by Marriott Florence 10/10 Excellent "Clean big room and nice staff" [](https://expedia.com/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent " Good breakfast" [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "Clean rooms and halls.The staff was very friendly and professional. The breakfast bar was clean with a nice presentation. The hotel experience was very pleasant." [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 2/10 Terrible "Had to leave and book another hotel because of cockroaches!!! the reviews I had red were so not what we encounter. " [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/ffaddd2a_y.jpg) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 10/10 Excellent "Great overnight stop. The area was safe and clean." [](https://expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Residence Inn Marriott Florence](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/e08b1bcd_y.jpg) ### Residence Inn Marriott Florence 6/10 Okay "I booked the motel because Hotels.com showed a hot tub at this location.'t When I arrived and asked about it I was told they didn't have one. That was the only reason I booked it." [](https://expedia.com/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - [Flights from Florence Regional ](https://www.expedia.com/lp/airports/flo/flights-from-florence-regional-airport) - [Flights from New York (JFK) to Florence (FLO) ](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - 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