Title: Top Red Roof Inn in Florence, SC from $63 - Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 17 - Mar 18](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-17&endDate=2026-03-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 18 - Mar 19](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-18&endDate=2026-03-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence Red Roof Inn ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/76254b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/31819118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Non Smoking (Roll-In Shower) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/2b946657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12827/009ea869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Dillon, SC [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) Dillon 6.4/10 (1,001 reviews) "Room was clean, staff very helpful and kind. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge $56 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Dillon.h12827.Hotel-Information) ![Blackout drapes, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/ae830b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/4165fb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/bbdb0658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/2000000/1290000/1281500/1281499/33c86cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Sumter [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) Sumter 6.8/10 (289 reviews) "The lady that checked me in was super nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicole $110 nightly $123 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-Red-Roof-Inn-Sumter.h1281499.Hotel-Information) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/868ff462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/f14e88ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Florence 6.8/10 (1,004 reviews) "It met our needs for an overnight stay. Clean, quiet and safe. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) philip $56 nightly $63 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Desk, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/79100656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/fa0bcb0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/e212e1b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/24300/24204/3073a472.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Bishopville [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Bishopville.h24204.Hotel-Information) Bishopville 6.2/10 (139 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedrin $75 nightly $84 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Bishopville.h24204.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-31&endDate=2026-04-01®ionId=1221&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels) ## Top Florence Hotel Reviews ![Fairfield Inn & Suites by Marriott Florence I-20](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640_y.jpg) ### Fairfield Inn & Suites by Marriott Florence I-20 10/10 Excellent "We had been to Comfort Inn on our way to Florida and were not pleased. Picked this place on way back and it was great. Friendly check in staff, food good and way better tv. " [](https://expedia.com/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011_y.jpg) ### Comfort Inn & Suites Florence Center Area 8/10 Good "I would stay again. The floor above walking was a bit obnoxious. But I still had a good night sleep. Staff was pleasant." [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "Very clean rooms and nice staff. We always stay here when I'm Florence. Walking distance to all of downtown." [](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "We had a great stay.The continental breakfast could have been a little more robust, but for the price for the room it was great and the rooms were clean and everything was wonderful." [](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "The room was excellent" [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685_y.jpg) ### Quality Inn & Suites Florence Civic Center 10/10 Excellent "The staff at the desk are so nice and understanding and the housekeepers be on top everything. They are so clean and the room are really nice. " [](https://expedia.com/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Staybridge Suites Florence - Civic Center by IHG](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a_y.jpg) ### Staybridge Suites Florence - Civic Center by IHG 10/10 Excellent "Stayed for one night while traveling to Florida. Very comfortable one bedroom suite. " [](https://expedia.com/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Clean room, friendly staff and ample parking, breakfast is ok. " [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 6/10 Okay "Booked because it was the lowest price for not a Motel 6 or Red Roof. Small room, no problem. Big fridge. Free coffee in the AM. Property is run down but bed and bathroom were clean. " [](https://expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - [Flights from Florence Regional ](https://www.expedia.com/lp/airports/flo/flights-from-florence-regional-airport) - [Flights from New York (JFK) to Florence (FLO) ](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - 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