$125 Cheap Flights from Houston (IAH) to Florence (FLO)

View $125 flight on Tue, Apr 7, 2026Opens in a new window

Popular airlines from George Bush Intercontinental Airport (IAH) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Houston to Florence (IAH-FLO)

Prices were available within the past 7 days and start at $125 for one-way flights and $269 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Apr 16 - Sun, Apr 19
IAH
Houston
FLO
Florence
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Apr 16 from Houston to Florence, returning Sun, Apr 19, priced at $269 found 1 day ago
American Airlines
Mon, May 18 - Tue, Aug 11
IAH
Houston
FLO
Florence
$294 Roundtrip, found 17 hours ago
$294
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Mon, May 18 from Houston to Florence, returning Tue, Aug 11, priced at $294 found 17 hours ago
American Airlines
Thu, Apr 16 - Sun, Apr 19
IAH
Houston
FLO
Florence
$339 Roundtrip, found 1 day ago
$339
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Apr 16 from Houston to Florence, returning Sun, Apr 19, priced at $339 found 1 day ago
American Airlines
Wed, Apr 1 - Tue, Apr 21
IAH
Houston
FLO
Florence
$359 Roundtrip, found 4 days ago
$359
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 1 from Houston to Florence, returning Tue, Apr 21, priced at $359 found 4 days ago
American Airlines
Mon, May 18 - Tue, Aug 11
IAH
Houston
FLO
Florence
$364 Roundtrip, found 17 hours ago
$364
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Mon, May 18 from Houston to Florence, returning Tue, Aug 11, priced at $364 found 17 hours ago
American Airlines
Mon, May 4 - Wed, May 20
IAH
Houston
FLO
Florence
$364 Roundtrip, found 4 days ago
$364
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 4 from Houston to Florence, returning Wed, May 20, priced at $364 found 4 days ago
American Airlines
Wed, Mar 18 - Tue, Apr 7
IAH
Houston
FLO
Florence
$384 Roundtrip, found 4 days ago
$384
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Mar 18 from Houston to Florence, returning Tue, Apr 7, priced at $384 found 4 days ago
American Airlines
Thu, May 28 - Tue, Jun 2
IAH
Houston
FLO
Florence
$389 Roundtrip, found 1 day ago
$389
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 28 from Houston to Florence, returning Tue, Jun 2, priced at $389 found 1 day ago
American Airlines
Mon, May 4 - Sat, May 16
IAH
Houston
FLO
Florence
$389 Roundtrip, found 4 days ago
$389
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 4 from Houston to Florence, returning Sat, May 16, priced at $389 found 4 days ago
American Airlines
Mon, May 4 - Thu, May 21
IAH
Houston
FLO
Florence
$404 Roundtrip, found 4 days ago
$404
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, May 4 from Houston to Florence, returning Thu, May 21, priced at $404 found 4 days ago

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Alternative airports near Florence

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Florence Regional FLO. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $517
FLO
Florence Regional
CheapestClosest
Average driving time to city center5 min
Flights from $517

Frequently asked questions

How much does a flight from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO) cost?
Grab a cheap one-way flight from $125 or cheap return flight from $269 from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO)?
April is the cheapest month to fly from IAH to FLO. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll take you from IAH to FLO. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO)?
Direct flights from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from IAH to FLO?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO)?
To avoid possible delays on the George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO) route, fly before 3 PM. Later flights have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO) last-minute?
Last-minute bookings from IAH to FLO are typically more expensive. To secure the best rates, start looking for flights as early as possible. That said, if your travel plans are flexible, it's possible to find a cheap fare right before your journey.
Is it cheaper to book an IAH to FLO flight and hotel package?
Booking an IAH to FLO flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our extensive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO)?
Usually, it's possible to reschedule or cancel your IAH to FLO flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
George Bush Intercontinental
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$268
Distance
957 mi

Book with confidence

Houston to Florence Flights

The cheapest times to fly from Houston to Florence

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Houston to Florence are during the month of April. You can find some of the cheapest flights from Houston to Florence with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Houston to Florence

Sunday is one of the best days to book for cheap flights from Houston to Florence: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Houston to Florence

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Houston to Florence in 2026. You can also book with separate airlines for your outbound and return journeys, from $125 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Houston to Florence flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Houston to Florence airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Houston to Florence Flights

*Flight schedules are subject to change.

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