$155 Cheap Flights from Houston (IAH) to Florence (FLO)

View $155 flight on Fri, Apr 24, 2026Opens in a new window

Popular airlines from George Bush Intercontinental Airport (IAH) to Florence, SC (FLO-Florence Regional)

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Cheap Flights from Houston to Florence (IAH-FLO)

Prices were available within the past 7 days and start at $155 for one-way flights and $309 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, May 9 - Tue, May 12
IAH
Houston
FLO
Florence
$309 Roundtrip, just found
$309
Roundtrip
just found
Select American Airlines flight, departing Sat, May 9 from Houston to Florence, returning Tue, May 12, priced at $309 just found
American Airlines
Sat, Nov 14 - Sun, Nov 22
IAH
Houston
FLO
Florence
$329 Roundtrip, just found
$329
Roundtrip
just found
Select American Airlines flight, departing Sat, Nov 14 from Houston to Florence, returning Sun, Nov 22, priced at $329 just found
American Airlines
Fri, Jun 5 - Mon, Jun 8
IAH
Houston
FLO
Florence
$383 Roundtrip, found 3 days ago
$383
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jun 5 from Houston to Florence, returning Mon, Jun 8, priced at $383 found 3 days ago
American Airlines
Sat, May 9 - Tue, May 12
IAH
Houston
FLO
Florence
$416 Roundtrip, just found
$416
Roundtrip
just found
Select American Airlines flight, departing Sat, May 9 from Houston to Florence, returning Tue, May 12, priced at $416 just found
American Airlines
Sat, May 9 - Tue, May 12
IAH
Houston
FLO
Florence
$419 Roundtrip, just found
$419
Roundtrip
just found
Select American Airlines flight, departing Sat, May 9 from Houston to Florence, returning Tue, May 12, priced at $419 just found
American Airlines
Sat, May 9 - Tue, May 12
IAH
Houston
FLO
Florence
$421 Roundtrip, just found
$421
Roundtrip
just found
Select American Airlines flight, departing Sat, May 9 from Houston to Florence, returning Tue, May 12, priced at $421 just found
American Airlines
Thu, Apr 30 - Sun, May 3
IAH
Houston
FLO
Florence
$422 Roundtrip, found 5 days ago
$422
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Apr 30 from Houston to Florence, returning Sun, May 3, priced at $422 found 5 days ago
American Airlines
Sat, May 9 - Tue, May 12
IAH
Houston
FLO
Florence
$429 Roundtrip, just found
$429
Roundtrip
just found
Select American Airlines flight, departing Sat, May 9 from Houston to Florence, returning Tue, May 12, priced at $429 just found
American Airlines
Sat, May 9 - Tue, May 12
IAH
Houston
FLO
Florence
$433 Roundtrip, just found
$433
Roundtrip
just found
Select American Airlines flight, departing Sat, May 9 from Houston to Florence, returning Tue, May 12, priced at $433 just found
American Airlines
Sat, Nov 14 - Mon, Nov 23
IAH
Houston
FLO
Florence
$456 Roundtrip, just found
$456
Roundtrip
just found
Select American Airlines flight, departing Sat, Nov 14 from Houston to Florence, returning Mon, Nov 23, priced at $456 just found

Alternative airports near Florence

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Florence Regional FLO. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $565
FLO
Florence Regional
CheapestClosest
Average driving time to city center5 min
Flights from $565

Frequently asked questions

How much does a flight from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) cost?
You can find cheap one-way flights from $155 and cheap return flights from $309 Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) with Expedia. One-way flights generally range between $390 and $635, and roundtrip flights usually range from $248 to $1024. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
The cheapest month to fly from IAH to FLO is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
Enter IAH to FLO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Houston, TX (IAH) to Florence, SC (FLO) with a layover in O'Hare Intl. (ORD), starting from around $248. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
To find a cheap flight from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
The earliest flight from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) usually departs at around 6:00 AM, operated by American Airlines. This seasonal service is available in July, giving you a great opportunity to maximize your day upon arrival. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
The most popular departure times for flights from Houston (IAH) to Florence (FLO) are in the early morning, from 6am to 9am. About 39% of passengers prefer this time window. Many major carriers, including American Airlines, offer flights during this window. This timing is popular because it allows you to arrive in Florence with plenty of time to explore the area.
How long does it take to fly from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
A flight from IAH to FLO with a layover takes around 5 hours, with the route covering approximately 958 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
Select the "Business class" and "First class" filters when looking for IAH to FLO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) flight with Expedia?
It's easy to earn miles on a Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Florence from George Bush Intercontinental (IAH)?
When traveling from George Bush Intercontinental (IAH) to Florence, you can fly into Florence Regional (FLO) and Peretola (FLR). Some flights may connect through major hubs like O'Hare Intl. (ORD) before reaching Florence. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) at the last minute?
Typically, booking a last minute flight from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) flight and hotel package?
Securing a Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional)?
If you booked your Houston, TX (IAH-George Bush Intercontinental) to Florence, SC (FLO-Florence Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
George Bush Intercontinental
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$308
Distance
957 mi

*Flight schedules are subject to change.

*Available to One Key members.

 

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