$330 Cheap Flights from Dothan (DHN) to Knoxville (TYS)

View $330 flight on Sun, Oct 12, 2025Opens in a new window

Popular airlines from Dothan, AL (DHN-Dothan Regional) to McGhee Tyson Airport (TYS)

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Cheap Flights from Dothan to Knoxville (DHN-TYS)

Prices were available within the past 7 days and start at $330 for one-way flights and $307 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Dec 3 - Tue, Dec 9
DHN
Dothan
TYS
Knoxville
$307 Roundtrip, found 4 days ago
$307
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Dec 3 from Dothan to Knoxville, returning Tue, Dec 9, priced at $307 found 4 days ago
Delta
Wed, Dec 3 - Sat, Dec 6
DHN
Dothan
TYS
Knoxville
$317 Roundtrip, found 21 hours ago
$317
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, Dec 3 from Dothan to Knoxville, returning Sat, Dec 6, priced at $317 found 21 hours ago
Delta
Thu, Dec 4 - Sat, Dec 6
DHN
Dothan
TYS
Knoxville
$327 Roundtrip, found 4 days ago
$327
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Dec 4 from Dothan to Knoxville, returning Sat, Dec 6, priced at $327 found 4 days ago
Delta
Tue, Oct 28 - Fri, Nov 7
DHN
Dothan
TYS
Knoxville
$337 Roundtrip, found 22 hours ago
$337
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Oct 28 from Dothan to Knoxville, returning Fri, Nov 7, priced at $337 found 22 hours ago
Delta
Wed, Dec 3 - Sat, Dec 6
DHN
Dothan
TYS
Knoxville
$347 Roundtrip, found 21 hours ago
$347
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, Dec 3 from Dothan to Knoxville, returning Sat, Dec 6, priced at $347 found 21 hours ago
Delta
Wed, Dec 3 - Sun, Dec 7
DHN
Dothan
TYS
Knoxville
$347 Roundtrip, found 4 days ago
$347
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Dec 3 from Dothan to Knoxville, returning Sun, Dec 7, priced at $347 found 4 days ago
Delta
Fri, Dec 5 - Sat, Dec 6
DHN
Dothan
TYS
Knoxville
$357 Roundtrip, found 4 days ago
$357
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Dec 5 from Dothan to Knoxville, returning Sat, Dec 6, priced at $357 found 4 days ago
Delta
Mon, Nov 3 - Sun, Nov 9
DHN
Dothan
TYS
Knoxville
$357 Roundtrip, found 22 hours ago
$357
Roundtrip
found 22 hours ago
Select Delta flight, departing Mon, Nov 3 from Dothan to Knoxville, returning Sun, Nov 9, priced at $357 found 22 hours ago
Delta
Tue, Oct 28 - Sun, Nov 9
DHN
Dothan
TYS
Knoxville
$367 Roundtrip, found 22 hours ago
$367
Roundtrip
found 22 hours ago
Select Delta flight, departing Tue, Oct 28 from Dothan to Knoxville, returning Sun, Nov 9, priced at $367 found 22 hours ago
Delta
Wed, Dec 3 - Sat, Dec 6
DHN
Dothan
TYS
Knoxville
$377 Roundtrip, found 21 hours ago
$377
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, Dec 3 from Dothan to Knoxville, returning Sat, Dec 6, priced at $377 found 21 hours ago
Delta
Fri, Dec 5 - Mon, Dec 8
DHN
Dothan
TYS
Knoxville
$387 Roundtrip, found 4 days ago
$387
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Dec 5 from Dothan to Knoxville, returning Mon, Dec 8, priced at $387 found 4 days ago
Delta
Fri, Dec 5 - Sun, Dec 7
DHN
Dothan
TYS
Knoxville
$387 Roundtrip, found 4 days ago
$387
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Dec 5 from Dothan to Knoxville, returning Sun, Dec 7, priced at $387 found 4 days ago
Delta
Wed, Dec 3 - Sat, Dec 6
DHN
Dothan
TYS
Knoxville
$407 Roundtrip, found 21 hours ago
$407
Roundtrip
found 21 hours ago
Select Delta flight, departing Wed, Dec 3 from Dothan to Knoxville, returning Sat, Dec 6, priced at $407 found 21 hours ago
Delta
Mon, Nov 3 - Fri, Nov 7
DHN
Dothan
TYS
Knoxville
$407 Roundtrip, found 22 hours ago
$407
Roundtrip
found 22 hours ago
Select Delta flight, departing Mon, Nov 3 from Dothan to Knoxville, returning Fri, Nov 7, priced at $407 found 22 hours ago
Delta
Thu, Oct 30 - Tue, Nov 4
DHN
Dothan
TYS
Knoxville
$413 Roundtrip, found 22 hours ago
$413
Roundtrip
found 22 hours ago
Select Delta flight, departing Thu, Oct 30 from Dothan to Knoxville, returning Tue, Nov 4, priced at $413 found 22 hours ago

Frequently asked questions

How much does a flight from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS) cost?
Secure a cheap one-way flight from $330 or cheap return flight from $307 from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS)?
Planning your trip for December is a good way to save, as it's the cheapest month for flights between DHN and TYS. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS)?
To find the cheapest airline flying from DHN to TYS, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS)?
There are no daily direct flights departing from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from DHN to TYS?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS)?
Opt for a flight from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS) last-minute?
Last-minute fares from DHN to TYS are typically more expensive. To secure the lowest prices, start looking for flights as early as possible. That being said, if you're flexible with your travel plans, it's possible to land a cheap ticket right before your journey.
Is it cheaper to book a DHN to TYS flight and hotel package?
Compared with arranging hotels and flights separately, booking a DHN to TYS flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place takes the hassle out of travel planning. Simply pick your flights and select from our extensive range of stays, then personalize your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Dothan Regional Airport (DHN) to McGhee Tyson Airport (TYS)?
Generally, it's possible to reschedule or cancel your DHN to TYS flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Travel information

Origin airport
Dothan Regional
Destination airport
McGhee Tyson
Airlines serving
Delta
Roundtrip price
$306
Distance
321 mi

Book with confidence

Book with confidence

Dothan to Knoxville Flights

The cheapest times to fly from Dothan to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Dothan to Knoxville are during the month of December. You can find some of the cheapest flights from Dothan to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Dothan to Knoxville

Sunday is one of the best days to book for cheap flights from Dothan to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Dothan to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Dothan to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $330 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Dothan to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Dothan to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Dothan to Knoxville Flights

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*Available to One Key members.