$479 Cheap Flights from Rome (FCO) to Panama City (ECP)

View $479 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Rome to Panama City (FCO-ECP)

Prices were available within the past 7 days and start at $479 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Snag a cheap one-way flight from $479 or cheap return flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP)?
Traveling in is a great way to save, as it's the cheapest month for flights between FCO and ECP. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from FCO to ECP. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP)?
Nonstop flights from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from FCO to ECP?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP)?
To land at Northwest Florida Beaches Intl. Airport (ECP) without delays, opt for a flight that takes off from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Booking your flight from FCO to ECP just before your trip is generally more expensive. However, if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a FCO to ECP flight and hotel package?
Securing a FCO to ECP flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our extensive range of hotels and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Fiumicino - Leonardo da Vinci Intl. Airport (FCO) to Northwest Florida Beaches Intl. Airport (ECP)?
In most cases, you're able to reschedule or cancel your FCO to ECP flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want further information, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Fiumicino - Leonardo da Vinci Intl.
Destination airport
Northwest Florida Beaches Intl.
Distance
5231 mi

Book with confidence

Book with confidence

Rome to Panama City Flights

The cheapest times to fly from Rome to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Rome to Panama City are during the month of . You can find some of the cheapest flights from Rome to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Rome to Panama City

Sunday is one of the best days to book for cheap flights from Rome to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Rome to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Rome to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $479 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Rome to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Rome to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Rome to Panama City Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.