$66 Cheap Flights from Sioux Falls (FSD) to St. Louis (STL)

View $66 flight on Thu, Nov 13, 2025Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Sioux Falls to St. Louis (FSD-STL)

Prices were available within the past 7 days and start at $66 for one-way flights and $120 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Mon, Nov 17 - Sat, Dec 6
FSD
Sioux Falls
STL
St. Louis
$120 Roundtrip, found 3 days ago
$120
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Nov 17 from Sioux Falls to St. Louis, returning Sat, Dec 6, priced at $120 found 3 days ago
Frontier Airlines
Thu, Nov 13 - Sat, Nov 15
FSD
Sioux Falls
STL
St. Louis
$140 Roundtrip, found 21 hours ago
$140
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Thu, Nov 13 from Sioux Falls to St. Louis, returning Sat, Nov 15, priced at $140 found 21 hours ago
Frontier Airlines
Mon, Nov 10 - Thu, Nov 20
FSD
Sioux Falls
STL
St. Louis
$142 Roundtrip, found 3 days ago
$142
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Sioux Falls to St. Louis, returning Thu, Nov 20, priced at $142 found 3 days ago
Frontier Airlines
Mon, Nov 10 - Wed, Nov 12
FSD
Sioux Falls
STL
St. Louis
$153 Roundtrip, found 1 day ago
$153
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Sioux Falls to St. Louis, returning Wed, Nov 12, priced at $153 found 1 day ago
Frontier Airlines
Mon, Nov 17 - Wed, Dec 3
FSD
Sioux Falls
STL
St. Louis
$160 Roundtrip, found 3 days ago
$160
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Nov 17 from Sioux Falls to St. Louis, returning Wed, Dec 3, priced at $160 found 3 days ago
Frontier Airlines
Mon, Nov 10 - Sun, Nov 16
FSD
Sioux Falls
STL
St. Louis
$173 Roundtrip, found 3 days ago
$173
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Sioux Falls to St. Louis, returning Sun, Nov 16, priced at $173 found 3 days ago
Frontier Airlines
Thu, Nov 6 - Wed, Nov 12
FSD
Sioux Falls
STL
St. Louis
$179 Roundtrip, found 1 day ago
$179
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Nov 6 from Sioux Falls to St. Louis, returning Wed, Nov 12, priced at $179 found 1 day ago
American Airlines
Wed, Dec 17 - Fri, Jan 9
FSD
Sioux Falls
STL
St. Louis
$229 Roundtrip, just found
$229
Roundtrip
just found
Select American Airlines flight, departing Wed, Dec 17 from Sioux Falls to St. Louis, returning Fri, Jan 9, priced at $229 just found
Delta
Tue, Feb 24 - Sat, Feb 28
FSD
Sioux Falls
STL
St. Louis
$229 Roundtrip, found 4 hours ago
$229
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Feb 24 from Sioux Falls to St. Louis, returning Sat, Feb 28, priced at $229 found 4 hours ago
United
Wed, Dec 17 - Fri, Jan 9
FSD
Sioux Falls
STL
St. Louis
$229 Roundtrip, just found
$229
Roundtrip
just found
Select United flight, departing Wed, Dec 17 from Sioux Falls to St. Louis, returning Fri, Jan 9, priced at $229 just found

Find the cheapest month to fly from Sioux Falls (FSD) to St. Louis (STL)

May is typically the cheapest month to fly

From $198 - $418 per traveler.

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $304
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $304

Frequently asked questions

How much does a flight from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) cost?
Lock in a cheap one-way flight from $66 or cheap return flight from $120 from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
Planning your trip for November is a great way to save, as it's the cheapest month for flights between FSD and STL. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
To find the cheapest airline that'll fly you from FSD to STL, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
There are no daily nonstop flights departing from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL). But you can opt for flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from FSD to STL?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
Book a flight from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) that takes off before 3 PM to reduce the risk of cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Booking your flight from FSD to STL right before your getaway is typically more expensive. But if you're flexible with your schedule, you could land a cheap last-minute fare.
Is it cheaper to book a FSD to STL flight and hotel package?
You'll generally save money by securing a FSD to STL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've selected your ideal accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Sioux Falls Regional Airport (FSD) to Lambert-St. Louis Intl. Airport (STL)?
Generally, it's possible to cancel or reschedule your FSD to STL flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Sioux Falls Regional
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$120
Distance
470 mi

Book with confidence

Sioux Falls to St. Louis Flights

The cheapest times to fly from Sioux Falls to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to St. Louis are during the month of November. You can find some of the cheapest flights from Sioux Falls to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to St. Louis

Sunday is one of the best days to book for cheap flights from Sioux Falls to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $66 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sioux Falls to St. Louis Flights

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*Available to One Key members.