
Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Brussels Airport (BRU)
- Lufthansa
Lufthansa
- Air Canada
Air Canada
- American Airlines
American Airlines
- Finnair
Finnair
- Delta
Delta
- KLM
KLM
- United
United
- Plan, book, fly with confidence
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Cheap Flights from Greenville to Brussels (GSP-BRU)
Prices were available within the past 7 days and start at $468 for one-way flights and $626 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Alternative airports near Brussels
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Greenville-Spartanburg Intl. |
Destination airport | Brussels - National |
Airlines serving | Air Canada, American Airlines, Austrian Airlines, British Airways, Brussels Airlines, Delta, Finnair, KLM, Lufthansa, Scandinavian Airlines, United, Virgin Atlantic |
Roundtrip price | $626 |
Distance | 4264 mi |
Greenville to Brussels Flights
The cheapest times to fly from Greenville to Brussels
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Brussels are during the month of October. You can find some of the cheapest flights from Greenville to Brussels with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Greenville to Brussels
Sunday is one of the best days to book for cheap flights from Greenville to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Greenville to Brussels
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $468 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Greenville
- Greenville to Chicago (GSP - ORD)
- Greenville to Newark Liberty Intl. Airport (GSP - EWR)
- Greenville to Los Angeles (GSP - LAX)
- Greenville to Washington (GSP - DCA)
- Greenville to Miami (GSP - MIA)
- Greenville to Tampa (GSP - TPA)
- Greenville to New York (GSP - LGA)
- Greenville to Fort Lauderdale (GSP - FLL)
- Greenville to Boston (GSP - BOS)
- Greenville to Denver (GSP - DEN)
- Greenville to New York (GSP - JFK)
- Greenville to Seattle (GSP - SEA)
Top Routes to Brussels
- Chicago to Brussels (ORD - BRU)
- Newark Liberty Intl. Airport to Brussels (EWR - BRU)
- Los Angeles to Brussels (LAX - BRU)
- Washington to Brussels (DCA - BRU)
- Miami to Brussels (MIA - BRU)
- Boston to Brussels (BOS - BRU)
- New York to Brussels (LGA - BRU)
- Fort Lauderdale to Brussels (FLL - BRU)
- Minneapolis to Brussels (MSP - BRU)
- Washington to Brussels (IAD - BRU)
- New York to Brussels (JFK - BRU)
- Seattle to Brussels (SEA - BRU)
Top Routes from Greenville
- American Airlines Greenville to Chicago
- Delta Greenville to Newark Liberty Intl. Airport
- Delta Greenville to Los Angeles
- American Airlines Greenville to Washington
- American Airlines Greenville to Miami
- American Airlines Greenville to Tampa
- Delta Greenville to New York
- Delta Greenville to Fort Lauderdale
- Delta Greenville to Boston
- Delta Greenville to Denver
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Antwerp
Asheville
Nearby Airports
- Asheville Regional Airport (AVL)
- Charlotte-Douglas Intl. Airport (CLT)
- Columbia Metropolitan Airport (CAE)
- Concord Regional Airport (USA)
- Augusta Regional Airport (AGS)
- Tri-Cities Regional Airport (TRI)
- McGhee Tyson Airport (TYS)
- Virginia Highlands Airport (VJI)
- DeKalb-Peachtree Airport (PDK)
- Smith Reynolds Airport (INT)
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