$248 Cheap Flights from Hyannis (HYA) to San Diego (SAN)

View $248 flight on Thu, Jan 8, 2026Opens in a new window

Popular airlines from Hyannis, MA (HYA-Barnstable Municipal) to San Diego Intl. Airport (SAN)

Cheap Flights from Hyannis to San Diego (HYA-SAN)

Prices were available within the past 7 days and start at $248 for one-way flights and $621 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cape Air
Sun, Dec 7 - Wed, Dec 17
HYA
Hyannis
SAN
San Diego
$621 Roundtrip, found 19 hours ago
$621
Roundtrip
found 19 hours ago
Select Cape Air flight, departing Sun, Dec 7 from Hyannis to San Diego, returning Wed, Dec 17, priced at $621 found 19 hours ago
Cape Air
Sun, Dec 7 - Wed, Dec 17
HYA
Hyannis
SAN
San Diego
$627 Roundtrip, found 19 hours ago
$627
Roundtrip
found 19 hours ago
Select Cape Air flight, departing Sun, Dec 7 from Hyannis to San Diego, returning Wed, Dec 17, priced at $627 found 19 hours ago
JetBlue Airways
Sun, Dec 7 - Wed, Dec 17
HYA
Hyannis
SAN
San Diego
$695 Roundtrip, found 19 hours ago
$695
Roundtrip
found 19 hours ago
Select JetBlue Airways flight, departing Sun, Dec 7 from Hyannis to San Diego, returning Wed, Dec 17, priced at $695 found 19 hours ago
JetBlue Airways
Sun, Dec 7 - Wed, Dec 17
HYA
Hyannis
SAN
San Diego
$707 Roundtrip, found 19 hours ago
$707
Roundtrip
found 19 hours ago
Select JetBlue Airways flight, departing Sun, Dec 7 from Hyannis to San Diego, returning Wed, Dec 17, priced at $707 found 19 hours ago
Cape Air
Sun, Dec 7 - Wed, Dec 17
HYA
Hyannis
SAN
San Diego
$780 Roundtrip, found 19 hours ago
$780
Roundtrip
found 19 hours ago
Select Cape Air flight, departing Sun, Dec 7 from Hyannis to San Diego, returning Wed, Dec 17, priced at $780 found 19 hours ago
JetBlue Airways
Sun, Dec 7 - Wed, Dec 17
HYA
Hyannis
SAN
San Diego
$876 Roundtrip, found 19 hours ago
$876
Roundtrip
found 19 hours ago
Select JetBlue Airways flight, departing Sun, Dec 7 from Hyannis to San Diego, returning Wed, Dec 17, priced at $876 found 19 hours ago

Frequently asked questions

How much does a flight from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN) cost?
Get a cheap one-way flight from $248 or cheap return flight from $621 from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN)?
The cheapest month to fly from HYA to SAN is December, when there's less demand. Off-peak season is typically when airlines offer lower prices between these airports.
Which airlines fly direct from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN)?
You can't catch a direct flight from Hyannis, MA (HYA-Barnstable Municipal) to San Diego Intl. Airport (SAN). However, you can arrive in San Diego without any layovers by taking off from Logan Intl. Airport (BOS).
What is the cheapest airline that flies from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN)?
To find the cheapest airline that'll fly you from HYA to SAN, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN)?
You'll need to catch a flight with a layover when traveling from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from HYA to SAN?
Typically you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN)?
To avoid possible delays on the Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN) route, fly before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN) last-minute?
Last-minute fares from HYA to SAN are typically more expensive. To secure the best rates, start searching for flights well ahead of time. That said, if you're flexible with your travel dates, you may find a cheap ticket right before your trip.
Is it cheaper to book a HYA to SAN flight and hotel package?
Compared with arranging flights and hotels separately, booking a HYA to SAN flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one convenient place will take the stress out of travel planning. Just secure your flights and select from our wide range of stays, then tailor your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Barnstable Municipal Airport (HYA) to San Diego Intl. Airport (SAN)?
It's usually possible to cancel or reschedule your HYA to SAN flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Barnstable Municipal
Destination airport
San Diego Intl.
Roundtrip price
$620
Distance
2620 mi

Book with confidence

Hyannis to San Diego Flights

The cheapest times to fly from Hyannis to San Diego

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Hyannis to San Diego are during the month of December. You can find some of the cheapest flights from Hyannis to San Diego with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Hyannis to San Diego

Sunday is one of the best days to book for cheap flights from Hyannis to San Diego: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Hyannis to San Diego

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Hyannis to San Diego in 2025. You can also book with separate airlines for your outbound and return journeys, from $248 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Hyannis to San Diego flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Hyannis to San Diego airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Hyannis to San Diego Flights

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*Available to One Key members.