$614 Cheap Flights from Manchester (MAN) to Knoxville (TYS)

View $614 flight on Mon, Jan 19, 2026Opens in a new window

Popular airlines from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)

Cheap Flights from Manchester to Knoxville (MAN-TYS)

Prices were available within the past 7 days and start at $614 for one-way flights and $780 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$780 Roundtrip, found 6 days ago
$780
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $780 found 6 days ago
Lufthansa
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$827 Roundtrip, found 6 days ago
$827
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $827 found 6 days ago
Lufthansa
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$829 Roundtrip, found 6 days ago
$829
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $829 found 6 days ago
Lufthansa
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$832 Roundtrip, found 6 days ago
$832
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $832 found 6 days ago
Brussels Airlines
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$834 Roundtrip, found 6 days ago
$834
Roundtrip
found 6 days ago
Select Brussels Airlines flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $834 found 6 days ago
British Airways
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$838 Roundtrip, found 6 days ago
$838
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $838 found 6 days ago
British Airways
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$846 Roundtrip, found 6 days ago
$846
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $846 found 6 days ago
Scandinavian Airlines
Sun, Nov 16 - Sun, Nov 23
MAN
Manchester
TYS
Knoxville
$851 Roundtrip, found 4 days ago
$851
Roundtrip
found 4 days ago
Select Scandinavian Airlines flight, departing Sun, Nov 16 from Manchester to Knoxville, returning Sun, Nov 23, priced at $851 found 4 days ago
British Airways
Thu, Jan 15 - Mon, Jan 19
MAN
Manchester
TYS
Knoxville
$855 Roundtrip, found 6 days ago
$855
Roundtrip
found 6 days ago
Select British Airways flight, departing Thu, Jan 15 from Manchester to Knoxville, returning Mon, Jan 19, priced at $855 found 6 days ago
American Airlines
Tue, Nov 11 - Wed, Nov 19
MAN
Manchester
TYS
Knoxville
$936 Roundtrip, found 4 days ago
$936
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Nov 11 from Manchester to Knoxville, returning Wed, Nov 19, priced at $936 found 4 days ago
Flights from Manchester (MAN) to Knoxville (TYS)
Origin airport
Manchester
Destination airport
McGhee Tyson
Airlines serving
Aer Lingus, American Airlines, British Airways, Brussels Airlines, Delta, KLM, Lufthansa, Scandinavian Airlines, United, Virgin Atlantic
Roundtrip price
$780
Distance
3963 mi

Manchester to Knoxville Flights

The cheapest times to fly from Manchester to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manchester to Knoxville are during the month of January. You can find some of the cheapest flights from Manchester to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manchester to Knoxville

Sunday is one of the best days to book for cheap flights from Manchester to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manchester to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manchester to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from $614 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manchester to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manchester to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Manchester Airport (MAN) to McGhee Tyson Airport (TYS) cost?
Grab a cheap one-way flight from $614 or cheap return flight from $780 from Manchester Airport (MAN) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)?
Flying in January may help you find better deals, as it's the cheapest month for flights between MAN and TYS. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)?
To find the cheapest airline flying from MAN to TYS, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)?
There aren't any daily nonstop flights available from Manchester Airport (MAN) to McGhee Tyson Airport (TYS). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from MAN to TYS?
Generally you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)?
To reach McGhee Tyson Airport (TYS) without delays, select a flight that leaves from Manchester Airport (MAN) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Manchester Airport (MAN) to McGhee Tyson Airport (TYS) last-minute?
Last-minute fares from MAN to TYS are usually more expensive. To secure the best rates, start searching for flights ahead of time. That said, if your travel plans are flexible, it's possible to land a cheap ticket right before you leave.
Is it cheaper to book a MAN to TYS flight and hotel package?
Compared with arranging hotels and flights separately, booking a MAN to TYS flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place will take the hassle out of travel planning. Simply secure your flights and select from our wide range of stays, then personalize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Manchester Airport (MAN) to McGhee Tyson Airport (TYS)?
Usually, it's possible to reschedule or cancel your MAN to TYS flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.