$195 Cheap Flights from Medford (MFR) to Myrtle Beach (MYR)

View $195 flight on Wed, Sep 3, 2025Opens in a new window

Popular airlines from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR)

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Cheap Flights from Medford to Myrtle Beach (MFR-MYR)

Prices were available within the past 7 days and start at $195 for one-way flights and $319 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Sep 24 - Tue, Sep 30
MFR
Medford
MYR
Myrtle Beach
$319 Roundtrip, found 3 days ago
$319
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Sep 24 from Medford to Myrtle Beach, returning Tue, Sep 30, priced at $319 found 3 days ago
Delta
Wed, Sep 24 - Sat, Sep 27
MFR
Medford
MYR
Myrtle Beach
$349 Roundtrip, found 3 days ago
$349
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Sep 24 from Medford to Myrtle Beach, returning Sat, Sep 27, priced at $349 found 3 days ago
Delta
Tue, Sep 23 - Wed, Sep 24
MFR
Medford
MYR
Myrtle Beach
$358 Roundtrip, found 3 days ago
$358
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Sep 23 from Medford to Myrtle Beach, returning Wed, Sep 24, priced at $358 found 3 days ago
Delta
Wed, Sep 3 - Wed, Sep 10
MFR
Medford
MYR
Myrtle Beach
$364 Roundtrip, found 1 day ago
$364
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Sep 3 from Medford to Myrtle Beach, returning Wed, Sep 10, priced at $364 found 1 day ago
Delta
Wed, Sep 24 - Sat, Oct 4
MFR
Medford
MYR
Myrtle Beach
$384 Roundtrip, found 3 days ago
$384
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Sep 24 from Medford to Myrtle Beach, returning Sat, Oct 4, priced at $384 found 3 days ago
Delta
Tue, Sep 23 - Wed, Sep 24
MFR
Medford
MYR
Myrtle Beach
$388 Roundtrip, found 3 days ago
$388
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Sep 23 from Medford to Myrtle Beach, returning Wed, Sep 24, priced at $388 found 3 days ago
Delta
Sat, Aug 30 - Tue, Sep 30
MFR
Medford
MYR
Myrtle Beach
$393 Roundtrip, found 5 days ago
$393
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Aug 30 from Medford to Myrtle Beach, returning Tue, Sep 30, priced at $393 found 5 days ago
United
Mon, Oct 27 - Tue, Nov 4
MFR
Medford
MYR
Myrtle Beach
$397 Roundtrip, found 5 days ago
$397
Roundtrip
found 5 days ago
Select United flight, departing Mon, Oct 27 from Medford to Myrtle Beach, returning Tue, Nov 4, priced at $397 found 5 days ago
American Airlines
Wed, Sep 3 - Wed, Sep 10
MFR
Medford
MYR
Myrtle Beach
$454 Roundtrip, found 1 day ago
$454
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 3 from Medford to Myrtle Beach, returning Wed, Sep 10, priced at $454 found 1 day ago
Alaska Airlines
Mon, Sep 15 - Mon, Sep 22
MFR
Medford
MYR
Myrtle Beach
$718 Roundtrip, found 11 hours ago
$718
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Mon, Sep 15 from Medford to Myrtle Beach, returning Mon, Sep 22, priced at $718 found 11 hours ago
Flights from Medford (MFR) to Myrtle Beach (MYR)
Origin airport
Rogue Valley Intl.
Destination airport
Myrtle Beach Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, United
Roundtrip price
$319
Distance
2437 mi

Medford to Myrtle Beach Flights

The cheapest times to fly from Medford to Myrtle Beach

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medford to Myrtle Beach are during the month of September. You can find some of the cheapest flights from Medford to Myrtle Beach with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medford to Myrtle Beach

Sunday is one of the best days to book for cheap flights from Medford to Myrtle Beach: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medford to Myrtle Beach

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medford to Myrtle Beach in 2025. You can also book with separate airlines for your outbound and return journeys, from $195 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medford to Myrtle Beach flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medford to Myrtle Beach airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR) cost?
Snag a cheap one-way flight from $195 or cheap return flight from $319 from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR)?
Planning your trip for September can help you save, as it's the cheapest month for flights between MFR and MYR. You'll often find the lowest prices during off-peak months.
What is the cheapest airline that flies from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from MFR to MYR. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR)?
Nonstop flights from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MFR to MYR?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR)?
To reach Myrtle Beach Intl. Airport (MYR) on time, pick a flight that takes off from Rogue Valley Intl. Airport (MFR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR) last-minute?
Last-minute fares from MFR to MYR are usually more expensive. For the best rates, start searching for flights well ahead of time. That said, if you're flexible with your travel plans, you may land a cheap fare right before your journey.
Is it cheaper to book a MFR to MYR flight and hotel package?
You'll typically save money by booking a MFR to MYR flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After choosing your preferred flights and accommodations, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Rogue Valley Intl. Airport (MFR) to Myrtle Beach Intl. Airport (MYR)?
If you booked your MFR to MYR flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

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*Available to One Key members.