$256 Cheap Flights from Manhattan (MHK) to St. Louis (STL)

View $256 flight on Tue, Oct 28, 2025Opens in a new window

Popular airlines from Manhattan, KS (MHK-Manhattan Regional) to St. Louis Lambert Intl. Airport (STL)

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Cheap Flights from Manhattan to St. Louis (MHK-STL)

Prices were available within the past 7 days and start at $256 for one-way flights and $400 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Nov 25 - Wed, Dec 10
MHK
Manhattan
STL
St. Louis
$400 Roundtrip, found 1 day ago
$400
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 25 from Manhattan to St. Louis, returning Wed, Dec 10, priced at $400 found 1 day ago
American Airlines
Fri, Nov 7 - Sat, Nov 8
MHK
Manhattan
STL
St. Louis
$410 Roundtrip, found 6 days ago
$410
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Nov 7 from Manhattan to St. Louis, returning Sat, Nov 8, priced at $410 found 6 days ago
American Airlines
Fri, Oct 31 - Fri, Nov 7
MHK
Manhattan
STL
St. Louis
$412 Roundtrip, found 6 days ago
$412
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Oct 31 from Manhattan to St. Louis, returning Fri, Nov 7, priced at $412 found 6 days ago
American Airlines
Tue, Nov 25 - Sat, Dec 6
MHK
Manhattan
STL
St. Louis
$420 Roundtrip, found 1 day ago
$420
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Nov 25 from Manhattan to St. Louis, returning Sat, Dec 6, priced at $420 found 1 day ago
American Airlines
Tue, Dec 23 - Tue, Jan 6
MHK
Manhattan
STL
St. Louis
$422 Roundtrip, found 1 day ago
$422
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 23 from Manhattan to St. Louis, returning Tue, Jan 6, priced at $422 found 1 day ago
American Airlines
Wed, Nov 19 - Wed, Dec 10
MHK
Manhattan
STL
St. Louis
$427 Roundtrip, found 1 day ago
$427
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 19 from Manhattan to St. Louis, returning Wed, Dec 10, priced at $427 found 1 day ago
American Airlines
Thu, Nov 20 - Wed, Dec 10
MHK
Manhattan
STL
St. Louis
$430 Roundtrip, found 1 day ago
$430
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Nov 20 from Manhattan to St. Louis, returning Wed, Dec 10, priced at $430 found 1 day ago
American Airlines
Thu, Nov 27 - Tue, Dec 16
MHK
Manhattan
STL
St. Louis
$431 Roundtrip, found 1 day ago
$431
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Nov 27 from Manhattan to St. Louis, returning Tue, Dec 16, priced at $431 found 1 day ago
American Airlines
Mon, Nov 24 - Sat, Dec 6
MHK
Manhattan
STL
St. Louis
$440 Roundtrip, found 1 day ago
$440
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Nov 24 from Manhattan to St. Louis, returning Sat, Dec 6, priced at $440 found 1 day ago
American Airlines
Wed, Nov 5 - Sat, Nov 22
MHK
Manhattan
STL
St. Louis
$442 Roundtrip, found 1 day ago
$442
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 5 from Manhattan to St. Louis, returning Sat, Nov 22, priced at $442 found 1 day ago

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $400
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $400

Frequently asked questions

How much does a flight from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL) cost?
Get a cheap one-way flight from $256 or cheap return flight from $400 from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL)?
November is the cheapest month to fly from MHK to STL. Traveling during quieter months is often the key to better flight prices.
What is the cheapest airline that flies from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from MHK to STL. Then, sort your results by "Price (lowest to highest)" to score a great deal.
How many flights per day from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL)?
Nonstop flights from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MHK to STL?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on a range of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL)?
To avoid potential delays on the Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL) route, fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL) last-minute?
Waiting until just before your departure to book a ticket from MHK to STL generally means paying more. Although you may find some last-minute discounts, they aren't always guaranteed. Allow some flexibility in your schedule for the best chance of landing a bargain.
Is it cheaper to book a MHK to STL flight and hotel package?
You'll generally save money by securing a MHK to STL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras like car rentals, tours and activities.
Can I cancel or change the date of my flight from Manhattan Regional Airport (MHK) to Lambert-St. Louis Intl. Airport (STL)?
In most cases, you can cancel or modify your MHK to STL flight. However, additional fees may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more details, head to our Customer Service portal.

Travel information

Origin airport
Manhattan Regional
Destination airport
Lambert-St. Louis Intl.
Airlines serving
American Airlines
Roundtrip price
$400
Distance
339 mi

Book with confidence

Manhattan to St. Louis Flights

The cheapest times to fly from Manhattan to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manhattan to St. Louis are during the month of November. You can find some of the cheapest flights from Manhattan to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manhattan to St. Louis

Sunday is one of the best days to book for cheap flights from Manhattan to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manhattan to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manhattan to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from $256 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manhattan to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manhattan to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Manhattan to St. Louis Flights

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*Available to One Key members.