$239 Cheap Flights from Moline (MLI) to Buffalo (BUF)

View $239 flight on Sun, Oct 19, 2025Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Moline to Buffalo (MLI-BUF)

Prices were available within the past 7 days and start at $239 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Nov 14 - Sat, Nov 15
MLI
Moline
BUF
Buffalo
$249 Roundtrip, found 15 hours ago
$249
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Fri, Nov 14 from Moline to Buffalo, returning Sat, Nov 15, priced at $249 found 15 hours ago
Delta
Tue, Oct 21 - Tue, Oct 28
MLI
Moline
BUF
Buffalo
$254 Roundtrip, found 3 days ago
$254
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Oct 21 from Moline to Buffalo, returning Tue, Oct 28, priced at $254 found 3 days ago
United
Fri, Oct 17 - Mon, Oct 20
MLI
Moline
BUF
Buffalo
$266 Roundtrip, found 5 days ago
$266
Roundtrip
found 5 days ago
Select United flight, departing Fri, Oct 17 from Moline to Buffalo, returning Mon, Oct 20, priced at $266 found 5 days ago
Delta
Fri, Oct 24 - Wed, Oct 29
MLI
Moline
BUF
Buffalo
$274 Roundtrip, found 3 days ago
$274
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Oct 24 from Moline to Buffalo, returning Wed, Oct 29, priced at $274 found 3 days ago
United
Tue, Jun 9 - Sat, Jun 13
MLI
Moline
BUF
Buffalo
$275 Roundtrip, found 4 days ago
$275
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jun 9 from Moline to Buffalo, returning Sat, Jun 13, priced at $275 found 4 days ago
United
Mon, Jun 8 - Sat, Jun 13
MLI
Moline
BUF
Buffalo
$278 Roundtrip, found 4 days ago
$278
Roundtrip
found 4 days ago
Select United flight, departing Mon, Jun 8 from Moline to Buffalo, returning Sat, Jun 13, priced at $278 found 4 days ago
Delta
Fri, Oct 24 - Tue, Oct 28
MLI
Moline
BUF
Buffalo
$279 Roundtrip, found 3 days ago
$279
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Oct 24 from Moline to Buffalo, returning Tue, Oct 28, priced at $279 found 3 days ago
Delta
Wed, Oct 15 - Tue, Oct 28
MLI
Moline
BUF
Buffalo
$284 Roundtrip, found 5 days ago
$284
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Oct 15 from Moline to Buffalo, returning Tue, Oct 28, priced at $284 found 5 days ago
United
Fri, Oct 17 - Mon, Oct 20
MLI
Moline
BUF
Buffalo
$290 Roundtrip, found 5 days ago
$290
Roundtrip
found 5 days ago
Select United flight, departing Fri, Oct 17 from Moline to Buffalo, returning Mon, Oct 20, priced at $290 found 5 days ago
American Airlines
Fri, Nov 14 - Sat, Nov 15
MLI
Moline
BUF
Buffalo
$293 Roundtrip, found 15 hours ago
$293
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Fri, Nov 14 from Moline to Buffalo, returning Sat, Nov 15, priced at $293 found 15 hours ago

Frequently asked questions

How much does a flight from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF) cost?
Snag a cheap one-way flight from $239 or cheap return flight from $249 from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF)?
The cheapest month to fly from MLI to BUF is November, when there's less demand. Off-peak months are typically when airlines offer better prices between these airports.
What is the cheapest airline that flies from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MLI to BUF flight.
How many flights per day from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF)?
There aren't any daily nonstop flights departing from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from MLI to BUF?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF)?
To arrive at Buffalo Niagara Intl. Airport (BUF) without delays, book a flight that leaves Quad City Intl. Airport (MLI) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF) last-minute?
Holding off until just before your departure to book a flight from MLI to BUF generally means paying more. While you might find some last-minute offers, they're not always guaranteed. Allow some flexibility in your schedule to maximize your chances of scoring a bargain.
Is it cheaper to book a MLI to BUF flight and hotel package?
Securing a MLI to BUF flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our impressive range of stays and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quad City Intl. Airport (MLI) to Buffalo Niagara Intl. Airport (BUF)?
In most cases, you can modify or cancel your MLI to BUF flight. However, additional charges may apply, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you'd like further details, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Quad City Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
610 mi

Book with confidence

Book with confidence

Moline to Buffalo Flights

The cheapest times to fly from Moline to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to Buffalo are during the month of November. You can find some of the cheapest flights from Moline to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Moline to Buffalo

Sunday is one of the best days to book for cheap flights from Moline to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Moline to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to Buffalo in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Moline to Buffalo Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.