Cheap Flights from Durham (MME) to Knoxville (TYS)

Popular airlines from Durham (MME-Teesside Intl.) to McGhee Tyson Airport (TYS)

Cheap Flights from Durham to Knoxville (MME-TYS)

Prices were available within the past 7 days and start at for one-way flights and $1,037 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,037 Roundtrip, found 4 days ago
$1,037
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,037 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,042 Roundtrip, found 4 days ago
$1,042
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,042 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,059 Roundtrip, found 4 days ago
$1,059
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,059 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,064 Roundtrip, found 4 days ago
$1,064
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,064 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,100 Roundtrip, found 4 days ago
$1,100
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,100 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,105 Roundtrip, found 4 days ago
$1,105
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,105 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,123 Roundtrip, found 4 days ago
$1,123
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,123 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,140 Roundtrip, found 4 days ago
$1,140
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,140 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,145 Roundtrip, found 4 days ago
$1,145
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,145 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,163 Roundtrip, found 4 days ago
$1,163
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,163 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,168 Roundtrip, found 4 days ago
$1,168
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,168 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,184 Roundtrip, found 4 days ago
$1,184
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,184 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,189 Roundtrip, found 4 days ago
$1,189
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,189 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,194 Roundtrip, found 4 days ago
$1,194
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,194 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,199 Roundtrip, found 4 days ago
$1,199
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,199 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,203 Roundtrip, found 4 days ago
$1,203
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,203 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,205 Roundtrip, found 4 days ago
$1,205
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,205 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,207 Roundtrip, found 4 days ago
$1,207
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,207 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,208 Roundtrip, found 4 days ago
$1,208
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,208 found 4 days ago
Virgin Atlantic
Fri, Jan 16 - Mon, Jan 19
MME
Durham
TYS
Knoxville
$1,212 Roundtrip, found 4 days ago
$1,212
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Fri, Jan 16 from Durham to Knoxville, returning Mon, Jan 19, priced at $1,212 found 4 days ago

Frequently asked questions

How much does a flight from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS) cost?
Secure a cheap one-way flight or cheap return flight from $1,037 from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS)?
The cheapest month to fly from MME to TYS is January, when there's less demand. Off-peak season is typically when airlines offer better prices between these airports.
What is the cheapest airline that flies from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from MME to TYS. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS)?
You'll need to catch a flight with a layover when traveling from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from MME to TYS?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS)?
Book a flight from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS) last-minute?
Holding off until just before your departure to book a flight from MME to TYS generally means paying more. While you may come across some last-minute discounts, they aren't always guaranteed. Be flexible with your travel plans to maximize your chances of snagging a bargain.
Is it cheaper to book a MME to TYS flight and hotel package?
You can save money by booking a MME to TYS flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've selected your preferred accommodations and flights, you can add extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Teesside Intl. Airport (MME) to McGhee Tyson Airport (TYS)?
Typically, you can modify or cancel your MME to TYS flight. However, additional fees may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you'd like further information, go to our Customer Service portal.

Travel information

Origin airport
Teesside Intl.
Destination airport
McGhee Tyson
Roundtrip price
$1,036
Distance
3972 mi

Book with confidence

Durham to Knoxville Flights

The cheapest times to fly from Durham to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Durham to Knoxville are during the month of January. You can find some of the cheapest flights from Durham to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Durham to Knoxville

Sunday is one of the best days to book for cheap flights from Durham to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Durham to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Durham to Knoxville in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Durham to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Durham to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Durham to Knoxville Flights

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*Available to One Key members.