$435 Cheap Flights from Minneapolis (MSP) to Guayaquil (GYE)

View $435 flight on Tue, Feb 10, 2026Opens in a new window

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE)

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Cheap Flights from Minneapolis to Guayaquil (MSP-GYE)

Prices were available within the past 7 days and start at $435 for one-way flights and $645 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Feb 22 - Tue, Mar 31
MSP
Minneapolis
GYE
Guayaquil
$645 Roundtrip, found 5 hours ago
$645
Roundtrip
found 5 hours ago
Select Delta flight, departing Sun, Feb 22 from Minneapolis to Guayaquil, returning Tue, Mar 31, priced at $645 found 5 hours ago
American Airlines
Sun, Feb 22 - Tue, Mar 31
MSP
Minneapolis
GYE
Guayaquil
$650 Roundtrip, found 5 hours ago
$650
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sun, Feb 22 from Minneapolis to Guayaquil, returning Tue, Mar 31, priced at $650 found 5 hours ago
Delta
Sun, Feb 1 - Thu, Feb 12
MSP
Minneapolis
GYE
Guayaquil
$655 Roundtrip, found 1 day ago
$655
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Feb 1 from Minneapolis to Guayaquil, returning Thu, Feb 12, priced at $655 found 1 day ago
American Airlines
Mon, Jan 12 - Wed, Jan 21
MSP
Minneapolis
GYE
Guayaquil
$660 Roundtrip, found 14 hours ago
$660
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Jan 12 from Minneapolis to Guayaquil, returning Wed, Jan 21, priced at $660 found 14 hours ago
American Airlines
Sun, Feb 22 - Tue, Mar 31
MSP
Minneapolis
GYE
Guayaquil
$663 Roundtrip, found 5 hours ago
$663
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sun, Feb 22 from Minneapolis to Guayaquil, returning Tue, Mar 31, priced at $663 found 5 hours ago
Delta
Thu, Feb 5 - Thu, Feb 12
MSP
Minneapolis
GYE
Guayaquil
$665 Roundtrip, found 1 day ago
$665
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Feb 5 from Minneapolis to Guayaquil, returning Thu, Feb 12, priced at $665 found 1 day ago
LATAM Airlines Group
Sun, Jan 18 - Tue, Jan 27
MSP
Minneapolis
GYE
Guayaquil
$665 Roundtrip, found 8 hours ago
$665
Roundtrip
found 8 hours ago
Select LATAM Airlines Group flight, departing Sun, Jan 18 from Minneapolis to Guayaquil, returning Tue, Jan 27, priced at $665 found 8 hours ago
American Airlines
Mon, Mar 16 - Wed, Mar 25
MSP
Minneapolis
GYE
Guayaquil
$669 Roundtrip, found 14 hours ago
$669
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Mon, Mar 16 from Minneapolis to Guayaquil, returning Wed, Mar 25, priced at $669 found 14 hours ago
United
Wed, Dec 10 - Wed, Dec 24
MSP
Minneapolis
GYE
Guayaquil
$1,087 Roundtrip, found 4 hours ago
$1,087
Roundtrip
found 4 hours ago
Select United flight, departing Wed, Dec 10 from Minneapolis to Guayaquil, returning Wed, Dec 24, priced at $1,087 found 4 hours ago
Copa
Mon, Feb 2 - Thu, Mar 5
MSP
Minneapolis
GYE
Guayaquil
$1,137 Roundtrip, found 22 hours ago
$1,137
Roundtrip
found 22 hours ago
Select Copa flight, departing Mon, Feb 2 from Minneapolis to Guayaquil, returning Thu, Mar 5, priced at $1,137 found 22 hours ago

Find the cheapest month to fly from Minneapolis (MSP) to Guayaquil (GYE)

January is typically the cheapest month to fly

From $383 - $1,250 per traveler.

Alternative airports near Guayaquil

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Joaquin de Olmedo Intl. GYE. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $850
GYE
Jose Joaquin de Olmedo Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $850

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE) cost?
Get a cheap one-way flight from $435 or cheap return flight from $645 from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
February is the cheapest month to fly from MSP to GYE. Traveling outside of peak seasons is often the key to scoring lower fares.
What is the cheapest airline that flies from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MSP to GYE flight.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
You'll need to hop on a flight with a layover if you're traveling from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from MSP to GYE?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Select a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE) last-minute?
Last-minute fares from MSP to GYE are typically more expensive. For the best rates, start searching for flights well ahead of time. That said, if your travel plans are flexible, it's possible to score a cheap fare right before you leave.
Is it cheaper to book a MSP to GYE flight and hotel package?
Compared with arranging hotels and flights separately, booking a MSP to GYE flight and hotel package with Expedia could result in significant savings. Better still, having everything in one place will take the hassle out of travel planning. Just pick your flights and choose from our extensive range of stays, then customize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Joaquin de Olmedo Intl. Airport (GYE)?
Generally, it's possible to cancel or reschedule your MSP to GYE flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Minneapolis - St. Paul Intl.
Destination airport
Jose Joaquin de Olmedo Intl.
Airlines serving
American Airlines, Copa, Delta, LATAM Airlines Group, United
Roundtrip price
$645
Distance
3351 mi

Book with confidence

Minneapolis to Guayaquil Flights

The cheapest times to fly from Minneapolis to Guayaquil

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Guayaquil are during the month of February. You can find some of the cheapest flights from Minneapolis to Guayaquil with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Minneapolis to Guayaquil

Sunday is one of the best days to book for cheap flights from Minneapolis to Guayaquil: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Minneapolis to Guayaquil

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Guayaquil in 2025. You can also book with separate airlines for your outbound and return journeys, from $435 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Guayaquil flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Minneapolis to Guayaquil airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Minneapolis to Guayaquil Flights

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*Available to One Key members.