$239 Cheap Flights from Roanoke (ROA) to Panama City (ECP)

View $239 flight on Tue, Oct 28, 2025Opens in a new window

Popular airlines from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP)

Cheap Flights from Roanoke to Panama City (ROA-ECP)

Prices were available within the past 7 days and start at $239 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Dec 3 - Tue, Dec 9
ROA
Roanoke
ECP
Panama City
$249 Roundtrip, found 17 hours ago
$249
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Dec 3 from Roanoke to Panama City, returning Tue, Dec 9, priced at $249 found 17 hours ago
American Airlines
Wed, Dec 3 - Tue, Dec 9
ROA
Roanoke
ECP
Panama City
$266 Roundtrip, found 17 hours ago
$266
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Wed, Dec 3 from Roanoke to Panama City, returning Tue, Dec 9, priced at $266 found 17 hours ago
Delta
Tue, Mar 24 - Tue, Mar 31
ROA
Roanoke
ECP
Panama City
$269 Roundtrip, found 6 hours ago
$269
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Mar 24 from Roanoke to Panama City, returning Tue, Mar 31, priced at $269 found 6 hours ago
Delta
Sat, Oct 25 - Sat, Nov 1
ROA
Roanoke
ECP
Panama City
$274 Roundtrip, found 11 hours ago
$274
Roundtrip
found 11 hours ago
Select Delta flight, departing Sat, Oct 25 from Roanoke to Panama City, returning Sat, Nov 1, priced at $274 found 11 hours ago
Delta
Thu, Nov 27 - Sun, Dec 14
ROA
Roanoke
ECP
Panama City
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Nov 27 from Roanoke to Panama City, returning Sun, Dec 14, priced at $279 found 2 days ago
American Airlines
Sat, Nov 15 - Mon, Nov 17
ROA
Roanoke
ECP
Panama City
$296 Roundtrip, found 6 days ago
$296
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Nov 15 from Roanoke to Panama City, returning Mon, Nov 17, priced at $296 found 6 days ago
Delta
Mon, Mar 23 - Tue, Mar 31
ROA
Roanoke
ECP
Panama City
$299 Roundtrip, found 6 hours ago
$299
Roundtrip
found 6 hours ago
Select Delta flight, departing Mon, Mar 23 from Roanoke to Panama City, returning Tue, Mar 31, priced at $299 found 6 hours ago
Delta
Tue, Nov 18 - Sun, Nov 23
ROA
Roanoke
ECP
Panama City
$308 Roundtrip, found 1 day ago
$308
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Nov 18 from Roanoke to Panama City, returning Sun, Nov 23, priced at $308 found 1 day ago
Delta
Tue, Oct 28 - Fri, Oct 31
ROA
Roanoke
ECP
Panama City
$311 Roundtrip, found 6 days ago
$311
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Oct 28 from Roanoke to Panama City, returning Fri, Oct 31, priced at $311 found 6 days ago
United
Sat, Oct 18 - Sat, Oct 25
ROA
Roanoke
ECP
Panama City
$359 Roundtrip, found 5 days ago
$359
Roundtrip
found 5 days ago
Select United flight, departing Sat, Oct 18 from Roanoke to Panama City, returning Sat, Oct 25, priced at $359 found 5 days ago

Frequently asked questions

How much does a flight from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Snag a cheap one-way flight from $239 or cheap return flight from $249 from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP)?
Flying in December is a great way to save, as it's the cheapest month for flights between ROA and ECP. You'll usually find the lowest prices during the off-season.
What is the cheapest airline that flies from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline that'll fly you from ROA to ECP, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP)?
You'll have to hop on a flight with a layover if you're traveling from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from ROA to ECP?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on various factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP)?
To avoid possible delays on the Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Last-minute fares from ROA to ECP are generally more expensive. To lock in the best prices, start searching for flights ahead of time. That said, if you're flexible with your travel plans, it's possible to land a cheap ticket just before your departure.
Is it cheaper to book a ROA to ECP flight and hotel package?
You'll typically save money by securing a ROA to ECP flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've chosen your ideal flights and accommodations, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Roanoke Regional Airport (ROA) to Northwest Florida Beaches Intl. Airport (ECP)?
You can usually reschedule or cancel your ROA to ECP flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Roanoke Regional
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
585 mi

Book with confidence

Book with confidence

Roanoke to Panama City Flights

The cheapest times to fly from Roanoke to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Roanoke to Panama City are during the month of December. You can find some of the cheapest flights from Roanoke to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Roanoke to Panama City

Sunday is one of the best days to book for cheap flights from Roanoke to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Roanoke to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Roanoke to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Roanoke to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Roanoke to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Roanoke to Panama City Flights

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*Available to One Key members.